HK1049795A1 - 用於治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 - Google Patents

用於治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 Download PDF

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Publication number
HK1049795A1
HK1049795A1 HK03101939.9A HK03101939A HK1049795A1 HK 1049795 A1 HK1049795 A1 HK 1049795A1 HK 03101939 A HK03101939 A HK 03101939A HK 1049795 A1 HK1049795 A1 HK 1049795A1
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HK
Hong Kong
Prior art keywords
mammal
compound
benzyl
ltb
atherosclerosis
Prior art date
Application number
HK03101939.9A
Other languages
English (en)
Chinese (zh)
Inventor
罗伯特‧J‧艾洛
羅伯特‧J‧艾洛
帕特里夏-安‧布拉萨
萨拉林‧林赛
帕特里夏-安‧布拉薩
薩拉林‧林賽
Original Assignee
辉瑞产品公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 辉瑞产品公司 filed Critical 辉瑞产品公司
Publication of HK1049795A1 publication Critical patent/HK1049795A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK03101939.9A 2001-06-28 2003-03-17 用於治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 HK1049795A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30171201P 2001-06-28 2001-06-28
US60/301,712 2001-06-28
US32825401P 2001-10-10 2001-10-10
US60/328,254 2001-10-10

Publications (1)

Publication Number Publication Date
HK1049795A1 true HK1049795A1 (zh) 2003-05-30

Family

ID=26972559

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03101939.9A HK1049795A1 (zh) 2001-06-28 2003-03-17 用於治疗动脉粥样硬化的苯甲酸取代的苯并吡喃

Country Status (12)

Country Link
EP (1) EP1270000A3 (enExample)
JP (1) JP2003034638A (enExample)
KR (1) KR20030015828A (enExample)
CN (1) CN1394602A (enExample)
AU (1) AU4239302A (enExample)
CA (1) CA2391205A1 (enExample)
CZ (1) CZ20022076A3 (enExample)
HK (1) HK1049795A1 (enExample)
HU (1) HUP0202114A3 (enExample)
IL (1) IL150340A0 (enExample)
PL (1) PL354770A1 (enExample)
SK (1) SK8682002A3 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4476934B2 (ja) * 2003-04-14 2010-06-09 明治乳業株式会社 新規ペプチドおよび免疫賦活剤、機能性食品ならびに機能性食品の製造方法
KR20070035101A (ko) * 2004-07-22 2007-03-29 파마시아 코포레이션 Ｃｏｘ-2 선택적 억제제 및 ｌｔｂ4 수용체 길항제의조합을 이용한 염증 및 통증 치료 조성물
JP5846711B2 (ja) * 2005-06-09 2016-01-20 メダ アーベー 炎症性疾患の治療のための方法及び組成物
US10336733B2 (en) 2015-11-30 2019-07-02 Merk Sharp & Dohme Corp. Aryl acylsulfonamides as BLT1 antagonists
EP3383389B1 (en) 2015-11-30 2021-04-28 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3720493A1 (de) * 1987-06-20 1989-01-26 Nattermann A & Cie Arzneizubereitungen mit mikronisierten ebselen-kristallen
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
DE4228200A1 (de) * 1992-08-25 1994-03-03 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
CN1160399A (zh) * 1994-10-13 1997-09-24 美国辉瑞有限公司 苯并吡喃和苯并稠合化合物、其制备方法和它们作为白三烯b4(ltb4)拮抗剂的用途
KR100232340B1 (ko) * 1994-10-13 1999-12-01 디. 제이. 우드, 스피겔 알렌 제이 류코트리엔 b4(ltb4) 길항물질로서의 벤조피란 및 벤조-축합된 화합물
CA2224563A1 (en) * 1995-06-12 1996-12-27 G.D. Searle & Co. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
JP3117730B2 (ja) * 1996-09-16 2000-12-18 ファイザー・インク 置換クロマール誘導体を製造するための方法及び中間体
EP0963755A3 (en) * 1998-04-16 2001-03-14 Pfizer Products Inc. Use of benzopyranes for preventing allograft rejection
AU5687199A (en) * 1998-08-24 2000-03-14 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
JP2003225088A (ja) * 1999-09-10 2003-08-12 Meiji Seika Kaisha Ltd ヒト・ロイコトリエンｂ４第二受容体及びそれをコードするｄｎａ
EP1268777A2 (en) * 2000-03-17 2003-01-02 Bayer Aktiengesellschaft Regulation of human leukotriene b 4?-like g protein-coupled receptor

Also Published As

Publication number Publication date
HU0202114D0 (enExample) 2002-09-28
CN1394602A (zh) 2003-02-05
CZ20022076A3 (cs) 2004-05-12
HUP0202114A2 (hu) 2003-01-28
KR20030015828A (ko) 2003-02-25
SK8682002A3 (en) 2004-08-03
AU4239302A (en) 2003-01-02
PL354770A1 (en) 2002-12-30
EP1270000A2 (en) 2003-01-02
EP1270000A3 (en) 2003-02-12
JP2003034638A (ja) 2003-02-07
IL150340A0 (en) 2002-12-01
HUP0202114A3 (en) 2004-07-28
CA2391205A1 (en) 2002-12-28

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