CN1394602A - 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 - Google Patents

用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 Download PDF

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Publication number
CN1394602A
CN1394602A CN02125125A CN02125125A CN1394602A CN 1394602 A CN1394602 A CN 1394602A CN 02125125 A CN02125125 A CN 02125125A CN 02125125 A CN02125125 A CN 02125125A CN 1394602 A CN1394602 A CN 1394602A
Authority
CN
China
Prior art keywords
treating atherosclerosis
compound
benzyl
carboxy
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN02125125A
Other languages
English (en)
Chinese (zh)
Inventor
罗伯特·J·艾洛
帕特里夏－安·布拉萨
萨拉林·林赛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of CN1394602A publication Critical patent/CN1394602A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN02125125A 2001-06-28 2002-06-28 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 Pending CN1394602A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30171201P 2001-06-28 2001-06-28
US60/301,712 2001-06-28
US32825401P 2001-10-10 2001-10-10
US60/328,254 2001-10-10

Publications (1)

Publication Number Publication Date
CN1394602A true CN1394602A (zh) 2003-02-05

Family

ID=26972559

Family Applications (1)

Application Number Title Priority Date Filing Date
CN02125125A Pending CN1394602A (zh) 2001-06-28 2002-06-28 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃

Country Status (12)

Country Link
EP (1) EP1270000A3 (enExample)
JP (1) JP2003034638A (enExample)
KR (1) KR20030015828A (enExample)
CN (1) CN1394602A (enExample)
AU (1) AU4239302A (enExample)
CA (1) CA2391205A1 (enExample)
CZ (1) CZ20022076A3 (enExample)
HK (1) HK1049795A1 (enExample)
HU (1) HUP0202114A3 (enExample)
IL (1) IL150340A0 (enExample)
PL (1) PL354770A1 (enExample)
SK (1) SK8682002A3 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004092206A1 (ja) * 2003-04-14 2004-10-28 Meiji Dairies Corporation 新規ペプチドおよび免疫賦活剤、機能性食品ならびに機能性食品の製造方法
EP1773396A1 (en) * 2004-07-22 2007-04-18 Pharmacia Corporation Compositions for treatment of inflammation and pain using a combination of a cox-2 selective inhibitor and a ltb4 receptor antagonist
EP1888033B1 (en) * 2005-06-09 2014-02-19 Meda AB Method and composition for treating inflammatory disorders
US10370368B2 (en) 2015-11-30 2019-08-06 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as BLT1 antagonists
US10336733B2 (en) 2015-11-30 2019-07-02 Merk Sharp & Dohme Corp. Aryl acylsulfonamides as BLT1 antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3720493A1 (de) * 1987-06-20 1989-01-26 Nattermann A & Cie Arzneizubereitungen mit mikronisierten ebselen-kristallen
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
DE4228200A1 (de) * 1992-08-25 1994-03-03 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
CN1160399A (zh) * 1994-10-13 1997-09-24 美国辉瑞有限公司 苯并吡喃和苯并稠合化合物、其制备方法和它们作为白三烯b4(ltb4)拮抗剂的用途
MX9702734A (es) * 1994-10-13 1997-06-28 Pfizer Benzopirano y compuestos benzocondensados, su preparacion y su uso como antagonistas de leucotrieno b4 (ltb4).
US6342510B1 (en) * 1995-06-12 2002-01-29 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
SK31399A3 (en) * 1996-09-16 2000-05-16 Pfizer Processes and intermediates for preparing substituted chromanol derivatives
EP0963755A3 (en) * 1998-04-16 2001-03-14 Pfizer Products Inc. Use of benzopyranes for preventing allograft rejection
WO2000010552A2 (en) * 1998-08-24 2000-03-02 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
JP2003225088A (ja) * 1999-09-10 2003-08-12 Meiji Seika Kaisha Ltd ヒト・ロイコトリエンｂ４第二受容体及びそれをコードするｄｎａ
AU3930201A (en) * 2000-03-17 2001-09-24 Bayer Aktiengesellschaft Regulation of human leukotriene B4-like G protein-coupled receptor

Also Published As

Publication number Publication date
HUP0202114A2 (hu) 2003-01-28
EP1270000A2 (en) 2003-01-02
KR20030015828A (ko) 2003-02-25
CZ20022076A3 (cs) 2004-05-12
HU0202114D0 (enExample) 2002-09-28
HK1049795A1 (zh) 2003-05-30
AU4239302A (en) 2003-01-02
EP1270000A3 (en) 2003-02-12
SK8682002A3 (en) 2004-08-03
HUP0202114A3 (en) 2004-07-28
PL354770A1 (en) 2002-12-30
CA2391205A1 (en) 2002-12-28
IL150340A0 (en) 2002-12-01
JP2003034638A (ja) 2003-02-07

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