HK1048819B - 新的配糖體、糖胺、酸、其中間體及其用途 - Google Patents

新的配糖體、糖胺、酸、其中間體及其用途

Info

Publication number
HK1048819B
HK1048819B HK02108876.0A HK02108876A HK1048819B HK 1048819 B HK1048819 B HK 1048819B HK 02108876 A HK02108876 A HK 02108876A HK 1048819 B HK1048819 B HK 1048819B
Authority
HK
Hong Kong
Prior art keywords
glycoconjugates
methods
present
acids
glycoamino
Prior art date
Application number
HK02108876.0A
Other languages
English (en)
Other versions
HK1048819A1 (en
Inventor
Samuel J Danishefsky
Jennifer R Allen
Govindaswami Ragupathi
Philip O Livingston
Lawrence Williams
Original Assignee
Sloan-Kettering Institute For Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan-Kettering Institute For Cancer Res filed Critical Sloan-Kettering Institute For Cancer Res
Publication of HK1048819A1 publication Critical patent/HK1048819A1/xx
Publication of HK1048819B publication Critical patent/HK1048819B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HK02108876.0A 1999-08-20 2002-12-05 新的配糖體、糖胺、酸、其中間體及其用途 HK1048819B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15008899P 1999-08-20 1999-08-20
PCT/US2000/022894 WO2001014395A2 (en) 1999-08-20 2000-08-18 Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof

Publications (2)

Publication Number Publication Date
HK1048819A1 HK1048819A1 (en) 2003-04-17
HK1048819B true HK1048819B (zh) 2006-11-10

Family

ID=22533089

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02108876.0A HK1048819B (zh) 1999-08-20 2002-12-05 新的配糖體、糖胺、酸、其中間體及其用途

Country Status (9)

Country Link
US (3) US7879335B1 (zh)
EP (1) EP1210355B1 (zh)
JP (2) JP5111705B2 (zh)
AT (1) ATE325803T1 (zh)
AU (1) AU6921300A (zh)
DE (1) DE60027905T2 (zh)
ES (1) ES2267559T3 (zh)
HK (1) HK1048819B (zh)
WO (1) WO2001014395A2 (zh)

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JP4308918B2 (ja) 1997-04-16 2009-08-05 スローン−ケッタリング インスティトゥート フォア キャンサー リサーチ （２，６）−ＳＴエピトープクラスターを有するα−Ｏ−結合複合糖質、その製造方法および使用
US7550146B2 (en) 1997-04-16 2009-06-23 Sloan-Kettering Institute For Cancer Research Glycopeptide conjugates and uses thereof
US7854934B2 (en) 1999-08-20 2010-12-21 Sloan-Kettering Institute For Cancer Research Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
US7824687B2 (en) 1999-08-20 2010-11-02 Sloan-Kettering Institute For Cancer Research Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
AU6921300A (en) * 1999-08-20 2001-03-19 Sloan-Kettering Institute For Cancer Research Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof
GB0314741D0 (en) * 2003-06-24 2003-07-30 Isis Innovation Reagents and methods
AU2006321554B2 (en) 2005-12-08 2012-08-02 E. R. Squibb & Sons, L.L.C. Human monoclonal antibodies to Fucosyl-GM1 and methods for using anti-Fucosyl-GM1
US8329635B2 (en) * 2006-06-20 2012-12-11 Bracco Imaging S.P.A. Method for the preparation of specific antibodies against saccharidic antigens
KR100849979B1 (ko) * 2006-12-06 2008-08-01 주식회사 삼천리제약 2-데옥시-엘-리보오스의 제조방법
EP1953237A1 (en) * 2007-02-01 2008-08-06 Ecover N.V. A method for the production of short chained glycolipids
EP2139524A1 (en) * 2007-03-23 2010-01-06 The Governors of the University of Alberta Multivalent heterobifunctional polymers and methods of their use
CA2734348A1 (en) * 2008-07-11 2010-01-14 Samuel Danishefsky Glycopeptide constructs and uses thereof
WO2011156774A2 (en) 2010-06-11 2011-12-15 Sloan-Kettering Institute For Cancer Research Multivalent glycopeptide constructs and uses thereof
JP6218085B2 (ja) * 2015-05-18 2017-10-25 国立大学法人信州大学 修飾キシロポリサッカライドの製造方法
KR20220012277A (ko) * 2019-05-24 2022-02-03 가부시키가이샤 도우사 고가쿠 겐큐쇼 신규 인공 단백질 촉매

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Also Published As

Publication number Publication date
HK1048819A1 (en) 2003-04-17
JP5111705B2 (ja) 2013-01-09
JP2012132025A (ja) 2012-07-12
EP1210355B1 (en) 2006-05-10
AU6921300A (en) 2001-03-19
DE60027905T2 (de) 2007-05-10
ATE325803T1 (de) 2006-06-15
US20110206757A1 (en) 2011-08-25
US7879335B1 (en) 2011-02-01
WO2001014395A3 (en) 2001-09-07
WO2001014395A2 (en) 2001-03-01
DE60027905D1 (de) 2006-06-14
US9464116B2 (en) 2016-10-11
JP2003507485A (ja) 2003-02-25
US8623378B2 (en) 2014-01-07
EP1210355A2 (en) 2002-06-05
US20140271817A1 (en) 2014-09-18
ES2267559T3 (es) 2007-03-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180818