HK1045945B - 稳定的丁苄唑啉和氧甲唑啉溶液 - Google Patents

稳定的丁苄唑啉和氧甲唑啉溶液 Download PDF

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Publication number
HK1045945B
HK1045945B HK02107497.1A HK02107497A HK1045945B HK 1045945 B HK1045945 B HK 1045945B HK 02107497 A HK02107497 A HK 02107497A HK 1045945 B HK1045945 B HK 1045945B
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HK
Hong Kong
Prior art keywords
solution according
active metal
solution
ions
weight
Prior art date
Application number
HK02107497.1A
Other languages
English (en)
Chinese (zh)
Other versions
HK1045945A1 (en
Inventor
弗里德‧U‧梅尔兹
弗里德‧U‧梅爾茲
Original Assignee
贝林格尔‧英格海姆国际有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23322017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1045945(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 贝林格尔‧英格海姆国际有限公司 filed Critical 贝林格尔‧英格海姆国际有限公司
Publication of HK1045945A1 publication Critical patent/HK1045945A1/xx
Publication of HK1045945B publication Critical patent/HK1045945B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Cosmetics (AREA)
HK02107497.1A 1999-06-22 2000-06-17 稳定的丁苄唑啉和氧甲唑啉溶液 HK1045945B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33778999A 1999-06-22 1999-06-22
US09/337,789 1999-06-22
PCT/EP2000/005583 WO2000078297A2 (de) 1999-06-22 2000-06-17 Stabile xylometazolin- und oxymetazolinlösung

Publications (2)

Publication Number Publication Date
HK1045945A1 HK1045945A1 (en) 2002-12-20
HK1045945B true HK1045945B (zh) 2005-01-28

Family

ID=23322017

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107497.1A HK1045945B (zh) 1999-06-22 2000-06-17 稳定的丁苄唑啉和氧甲唑啉溶液

Country Status (22)

Country Link
US (2) US20040191177A1 (enExample)
EP (1) EP1194145B1 (enExample)
JP (1) JP2003502361A (enExample)
KR (1) KR20020012001A (enExample)
CN (1) CN1164271C (enExample)
AT (1) ATE232099T1 (enExample)
AU (1) AU765736B2 (enExample)
BR (1) BR0011950A (enExample)
CA (1) CA2376121C (enExample)
CZ (1) CZ295595B6 (enExample)
DE (1) DE50001217D1 (enExample)
EA (1) EA003329B1 (enExample)
ES (1) ES2188563T3 (enExample)
HK (1) HK1045945B (enExample)
HU (1) HUP0201700A3 (enExample)
IL (1) IL147023A0 (enExample)
MX (1) MXPA01012912A (enExample)
PL (1) PL197542B1 (enExample)
PT (1) PT1194145E (enExample)
TR (1) TR200103694T2 (enExample)
WO (1) WO2000078297A2 (enExample)
ZA (1) ZA200110386B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1446119B1 (en) * 2001-09-18 2006-03-01 Nycomed Danmark ApS Compositions comprising ipatropium and xylometazoline for treatment of the common cold
CA2489528A1 (en) * 2002-06-20 2003-12-31 Novartis Consumer Health S.A. Nasal compositions comprising a mucopolysaccharide and propylene glycol
WO2004024187A2 (en) * 2002-09-13 2004-03-25 Zicam, Llc. Compositions to reduce congestion and methods for application thereof to the nasal membrane
DE10337186A1 (de) * 2003-08-13 2005-03-17 Merck Patent Gmbh Wässrige Wirkstoff-Lösung
US20090136598A1 (en) * 2006-04-26 2009-05-28 Aciex, Inc. Compositions for the Treatment and Prevention of Eyelid Swelling
EP2015733A2 (en) * 2006-04-26 2009-01-21 Aciex, Inc. Compositions for the treatment and prevention of eyelid swelling
CN101912363A (zh) * 2010-07-29 2010-12-15 蔡海德 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物
CN107249566A (zh) 2014-12-24 2017-10-13 加德兰-盖林斯基实验室有限责任公司 一种以海水作为赋形剂提高稳定性的鼻用组合物
WO2023046590A1 (en) 2021-09-22 2023-03-30 Jadran - Galenski Laboratorij D.D. An improved pharmaceutical composition for nasal use, preparation, and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603131A (en) * 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose
US4970240A (en) * 1989-10-18 1990-11-13 Schering Corporation Fruity flavored nasal decongestant composition
US5114979A (en) * 1989-10-18 1992-05-19 Schering Corporation Fruity flavored nasal decongestant composition
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
DE19549421C2 (de) * 1995-11-10 1999-11-18 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE19542959C1 (de) * 1995-11-17 1996-10-24 Ursatec Verpackung Gmbh Vor Kontamination schützende Abgabevorrichtung für Fluide
ES2190477T3 (es) * 1995-11-17 2003-08-01 Ursatec Verpackung Gmbh Dispensador de fluidos diseñado para proteger el contenido de la contaminacion.
JP4603687B2 (ja) * 1998-01-30 2010-12-22 ノバルテイス・コンシユーマー・ヘルス・エス・アー 点鼻用液剤

Also Published As

Publication number Publication date
PT1194145E (pt) 2003-06-30
BR0011950A (pt) 2002-03-12
EA200200042A1 (ru) 2002-06-27
HUP0201700A2 (hu) 2002-12-28
AU6150600A (en) 2001-01-09
JP2003502361A (ja) 2003-01-21
EA003329B1 (ru) 2003-04-24
TR200103694T2 (tr) 2002-04-22
MXPA01012912A (es) 2002-09-18
ES2188563T3 (es) 2003-07-01
HUP0201700A3 (en) 2003-02-28
ZA200110386B (en) 2003-04-22
IL147023A0 (en) 2002-08-14
CN1164271C (zh) 2004-09-01
ATE232099T1 (de) 2003-02-15
WO2000078297A2 (de) 2000-12-28
WO2000078297A3 (de) 2001-03-01
AU765736B2 (en) 2003-09-25
US20040191177A1 (en) 2004-09-30
CA2376121A1 (en) 2000-12-28
CA2376121C (en) 2008-06-10
PL352354A1 (en) 2003-08-11
CZ295595B6 (cs) 2005-08-17
KR20020012001A (ko) 2002-02-09
CN1361689A (zh) 2002-07-31
EP1194145A2 (de) 2002-04-10
CZ20014568A3 (cs) 2002-03-13
PL197542B1 (pl) 2008-04-30
HK1045945A1 (en) 2002-12-20
US20080011293A1 (en) 2008-01-17
DE50001217D1 (de) 2003-03-13
EP1194145B1 (de) 2003-02-05

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100617