HK1045858A1 - 指導進化的合成結扎再重合 - Google Patents
指導進化的合成結扎再重合Info
- Publication number
- HK1045858A1 HK1045858A1 HK02107285.7A HK02107285A HK1045858A1 HK 1045858 A1 HK1045858 A1 HK 1045858A1 HK 02107285 A HK02107285 A HK 02107285A HK 1045858 A1 HK1045858 A1 HK 1045858A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- directed evolution
- ligation reassembly
- synthetic ligation
- synthetic
- reassembly
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y308/00—Hydrolases acting on halide bonds (3.8)
- C12Y308/01—Hydrolases acting on halide bonds (3.8) in C-halide substances (3.8.1)
- C12Y308/01002—(S)-2-Haloacid dehalogenase (3.8.1.2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Ecology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/332,835 US6537776B1 (en) | 1999-06-14 | 1999-06-14 | Synthetic ligation reassembly in directed evolution |
PCT/US2000/016838 WO2000077262A1 (en) | 1999-06-14 | 2000-06-14 | Synthetic ligation reassembly in directed evolution |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1045858A1 true HK1045858A1 (zh) | 2002-12-13 |
Family
ID=23300064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02107285.7A HK1045858A1 (zh) | 1999-06-14 | 2002-10-03 | 指導進化的合成結扎再重合 |
Country Status (9)
Country | Link |
---|---|
US (5) | US6537776B1 (zh) |
EP (3) | EP2397549A3 (zh) |
JP (1) | JP4699662B2 (zh) |
AU (1) | AU5624600A (zh) |
CA (1) | CA2374667C (zh) |
HK (1) | HK1045858A1 (zh) |
IL (2) | IL146937A0 (zh) |
MX (1) | MXPA01013020A (zh) |
WO (1) | WO2000077262A1 (zh) |
Families Citing this family (177)
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US6991922B2 (en) | 1998-08-12 | 2006-01-31 | Proteus S.A. | Process for in vitro creation of recombinant polynucleotide sequences by oriented ligation |
US20040191772A1 (en) * | 1998-08-12 | 2004-09-30 | Dupret Daniel Marc | Method of shuffling polynucleotides using templates |
US6951719B1 (en) | 1999-08-11 | 2005-10-04 | Proteus S.A. | Process for obtaining recombined nucleotide sequences in vitro, libraries of sequences and sequences thus obtained |
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US20040005673A1 (en) * | 2001-06-29 | 2004-01-08 | Kevin Jarrell | System for manipulating nucleic acids |
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1999
- 1999-06-14 US US09/332,835 patent/US6537776B1/en not_active Expired - Lifetime
-
2000
- 2000-02-04 EP EP11167668A patent/EP2397549A3/en not_active Ceased
- 2000-06-14 EP EP00941550A patent/EP1192280A4/en not_active Ceased
- 2000-06-14 IL IL14693700A patent/IL146937A0/xx unknown
- 2000-06-14 MX MXPA01013020A patent/MXPA01013020A/es active IP Right Grant
- 2000-06-14 CA CA002374667A patent/CA2374667C/en not_active Expired - Fee Related
- 2000-06-14 US US09/594,459 patent/US6605449B1/en not_active Ceased
- 2000-06-14 AU AU56246/00A patent/AU5624600A/en not_active Abandoned
- 2000-06-14 JP JP2001503702A patent/JP4699662B2/ja not_active Expired - Fee Related
- 2000-06-14 WO PCT/US2000/016838 patent/WO2000077262A1/en active Application Filing
- 2000-06-14 EP EP20140195944 patent/EP2865754A1/en not_active Withdrawn
-
2001
- 2001-12-05 IL IL146937A patent/IL146937A/en not_active IP Right Cessation
-
2002
- 2002-10-03 HK HK02107285.7A patent/HK1045858A1/zh unknown
-
2003
- 2003-04-24 US US10/422,523 patent/US20040002103A1/en not_active Abandoned
-
2007
- 2007-05-09 US US11/798,032 patent/USRE45349E1/en not_active Expired - Lifetime
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2014
- 2014-12-23 US US14/581,571 patent/US20150119293A1/en not_active Abandoned
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WO2000077262A1 (en) | 2000-12-21 |
IL146937A0 (en) | 2002-08-14 |
WO2000077262A9 (en) | 2002-06-13 |
US20040002103A1 (en) | 2004-01-01 |
EP1192280A1 (en) | 2002-04-03 |
EP2865754A1 (en) | 2015-04-29 |
EP2397549A3 (en) | 2013-02-20 |
CA2374667A1 (en) | 2000-12-21 |
US20150119293A1 (en) | 2015-04-30 |
CA2374667C (en) | 2008-08-26 |
MXPA01013020A (es) | 2002-07-22 |
USRE45349E1 (en) | 2015-01-20 |
AU5624600A (en) | 2001-01-02 |
JP4699662B2 (ja) | 2011-06-15 |
EP2397549A2 (en) | 2011-12-21 |
IL146937A (en) | 2010-11-30 |
EP1192280A4 (en) | 2006-04-05 |
JP2004500027A (ja) | 2004-01-08 |
US6605449B1 (en) | 2003-08-12 |
US6537776B1 (en) | 2003-03-25 |
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