HK1045520A1 - 用於治療心臟心律不齊的雙哌啶類化合物 - Google Patents

用於治療心臟心律不齊的雙哌啶類化合物 Download PDF

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Publication number
HK1045520A1
HK1045520A1 HK02107165.2A HK02107165A HK1045520A1 HK 1045520 A1 HK1045520 A1 HK 1045520A1 HK 02107165 A HK02107165 A HK 02107165A HK 1045520 A1 HK1045520 A1 HK 1045520A1
Authority
HK
Hong Kong
Prior art keywords
treatment
compounds useful
cardiac arrhythmias
bispidine compounds
bispidine
Prior art date
Application number
HK02107165.2A
Other languages
English (en)
Chinese (zh)
Inventor
Alstermark Christer
Andersson Kjell
Bjore Annika
Bjorsne Magnus
Lindstedt Alstermark Eva-Lotte
Nilsson Goran
Polla Magnus
Strandlund Gert
Ortengren Ylva
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1045520A1 publication Critical patent/HK1045520A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK02107165.2A 1999-06-16 2000-06-15 用於治療心臟心律不齊的雙哌啶類化合物 HK1045520A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902268A SE9902268D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds
SE9902268-3 1999-06-16
PCT/SE2000/001254 WO2000077000A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
HK1045520A1 true HK1045520A1 (zh) 2002-11-29

Family

ID=20416100

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107165.2A HK1045520A1 (zh) 1999-06-16 2000-06-15 用於治療心臟心律不齊的雙哌啶類化合物

Country Status (24)

Country Link
EP (1) EP1192157A1 (enrdf_load_stackoverflow)
JP (1) JP2003502329A (enrdf_load_stackoverflow)
KR (1) KR20020010713A (enrdf_load_stackoverflow)
CN (1) CN1144805C (enrdf_load_stackoverflow)
AR (1) AR024577A1 (enrdf_load_stackoverflow)
AU (1) AU761576B2 (enrdf_load_stackoverflow)
BR (1) BR0011660A (enrdf_load_stackoverflow)
CA (1) CA2375841A1 (enrdf_load_stackoverflow)
CZ (1) CZ20014495A3 (enrdf_load_stackoverflow)
EE (1) EE200100675A (enrdf_load_stackoverflow)
HK (1) HK1045520A1 (enrdf_load_stackoverflow)
HU (1) HUP0203959A3 (enrdf_load_stackoverflow)
IL (1) IL146754A0 (enrdf_load_stackoverflow)
IS (1) IS6201A (enrdf_load_stackoverflow)
MX (1) MXPA01012919A (enrdf_load_stackoverflow)
NO (1) NO20016117L (enrdf_load_stackoverflow)
NZ (1) NZ516013A (enrdf_load_stackoverflow)
PL (1) PL354032A1 (enrdf_load_stackoverflow)
RU (1) RU2250903C2 (enrdf_load_stackoverflow)
SE (1) SE9902268D0 (enrdf_load_stackoverflow)
SK (1) SK18272001A3 (enrdf_load_stackoverflow)
TR (1) TR200103663T2 (enrdf_load_stackoverflow)
WO (1) WO2000077000A1 (enrdf_load_stackoverflow)
ZA (1) ZA200109796B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
SE0101327D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab New crystalline forms
TWI499418B (zh) * 2009-05-21 2015-09-11 Nerviano Medical Sciences Srl 異喹啉－１（２ｈ）－酮衍生物
KR101953407B1 (ko) * 2011-07-08 2019-02-28 바이엘 인텔렉쳐 프로퍼티 게엠베하 2-아미노-5-시아노-n,3-디메틸벤즈아미드의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1107541A1 (ru) * 1982-12-03 1995-10-20 Институт Тонкой Органической Химии Им.А.Л.Мнджояна 10-нитро-1,6,8-триазатрицикло [6,3,1,1] тридекан-2,5-дион
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
TW263504B (enrdf_load_stackoverflow) * 1991-10-03 1995-11-21 Pfizer
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
SE9902268D0 (sv) 1999-06-16
PL354032A1 (en) 2003-12-15
JP2003502329A (ja) 2003-01-21
WO2000077000A1 (en) 2000-12-21
CN1370167A (zh) 2002-09-18
TR200103663T2 (tr) 2002-05-21
CN1144805C (zh) 2004-04-07
BR0011660A (pt) 2002-03-26
NO20016117L (no) 2002-02-15
WO2000077000A9 (en) 2003-06-19
ZA200109796B (en) 2003-02-28
EE200100675A (et) 2003-02-17
CZ20014495A3 (cs) 2002-05-15
MXPA01012919A (es) 2002-07-30
EP1192157A1 (en) 2002-04-03
IS6201A (is) 2001-12-14
AU6032400A (en) 2001-01-02
HUP0203959A2 (hu) 2003-03-28
SK18272001A3 (sk) 2002-12-03
HUP0203959A3 (en) 2003-04-28
AU761576B2 (en) 2003-06-05
RU2250903C2 (ru) 2005-04-27
CA2375841A1 (en) 2000-12-21
NO20016117D0 (no) 2001-12-14
IL146754A0 (en) 2002-07-25
KR20020010713A (ko) 2002-02-04
NZ516013A (en) 2003-06-30
AR024577A1 (es) 2002-10-16

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