HK1040186A1 - 使用cd2-結合劑調節記憶效應t-細胞的方法和組合物 - Google Patents

使用cd2-結合劑調節記憶效應t-細胞的方法和組合物

Info

Publication number
HK1040186A1
HK1040186A1 HK02101435.9A HK02101435A HK1040186A1 HK 1040186 A1 HK1040186 A1 HK 1040186A1 HK 02101435 A HK02101435 A HK 02101435A HK 1040186 A1 HK1040186 A1 HK 1040186A1
Authority
HK
Hong Kong
Prior art keywords
cells
compositions
memory effector
modulating memory
modulating
Prior art date
Application number
HK02101435.9A
Other languages
English (en)
Inventor
D‧瑪吉拉維
Original Assignee
拜奧根有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 拜奧根有限公司 filed Critical 拜奧根有限公司
Publication of HK1040186A1 publication Critical patent/HK1040186A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70507CD2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2806Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2824Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD58
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
HK02101435.9A 1998-08-31 2002-02-26 使用cd2-結合劑調節記憶效應t-細胞的方法和組合物 HK1040186A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9845698P 1998-08-31 1998-08-31
PCT/US1999/020026 WO2000012113A2 (en) 1998-08-31 1999-08-31 Method of modulating memory effector t-cells using a cd2-binding agent, and compositions

Publications (1)

Publication Number Publication Date
HK1040186A1 true HK1040186A1 (zh) 2002-05-31

Family

ID=22269362

Family Applications (2)

Application Number Title Priority Date Filing Date
HK01108882A HK1038186A1 (en) 1998-08-31 2001-12-19 Modulation of memory effector t-cells with a cd2 binding agent
HK02101435.9A HK1040186A1 (zh) 1998-08-31 2002-02-26 使用cd2-結合劑調節記憶效應t-細胞的方法和組合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK01108882A HK1038186A1 (en) 1998-08-31 2001-12-19 Modulation of memory effector t-cells with a cd2 binding agent

Country Status (26)

Country Link
US (2) US20020009446A1 (zh)
EP (1) EP1109570B1 (zh)
JP (1) JP2002523071A (zh)
KR (1) KR20010085687A (zh)
CN (1) CN100473417C (zh)
AT (1) ATE306932T1 (zh)
AU (1) AU764020B2 (zh)
BR (1) BR9913285A (zh)
CA (1) CA2339299C (zh)
CZ (1) CZ298238B6 (zh)
DE (1) DE69927831T2 (zh)
DK (1) DK1109570T3 (zh)
EA (1) EA005948B1 (zh)
EE (1) EE200100123A (zh)
ES (1) ES2252999T3 (zh)
HK (2) HK1038186A1 (zh)
HU (1) HUP0103563A3 (zh)
IL (2) IL141486A0 (zh)
IS (1) IS5848A (zh)
MX (1) MXPA01002111A (zh)
NO (1) NO20010956L (zh)
NZ (1) NZ510831A (zh)
PL (1) PL346339A1 (zh)
TR (1) TR200100607T2 (zh)
WO (1) WO2000012113A2 (zh)
ZA (1) ZA200101213B (zh)

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PT1914244E (pt) 1999-04-09 2013-07-26 Kyowa Hakko Kirin Co Ltd Processo para regular a actividade de moléculas funcionais sob o ponto de vista imunológico
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
WO2002060480A1 (en) * 2001-02-01 2002-08-08 Biogen, Inc. Methods for treating or preventing skin disorders using cd2-binding agents
AU2002320352A1 (en) * 2001-07-24 2003-02-17 Biogen Idec Ma Inc. Methods for treating or preventing sclerotic disorders using cd2-binding agents
US7691568B2 (en) 2002-04-09 2010-04-06 Kyowa Hakko Kirin Co., Ltd Antibody composition-containing medicament
EP1641827A2 (en) * 2003-06-27 2006-04-05 Biogen Idec MA Inc. Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
WO2005035586A1 (ja) * 2003-10-08 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. 融合蛋白質組成物
MXPA06008918A (es) * 2004-02-06 2007-03-07 Astellas Llc Metodos de tratamiento de trastornos de la piel.
US20080020383A1 (en) * 2004-05-04 2008-01-24 Genaissance Pharmaceuticals, Inc. Haplotype Markers And Methods Of Using The Same To Determine Response To Treatment
EP1750747A1 (en) * 2004-05-07 2007-02-14 Astellas US LLC Soluble lfa-3 polypeptide for treating viral disorders
WO2006074399A2 (en) * 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
EP2021025B1 (en) * 2006-05-12 2016-08-17 ITH Immune Therapy Holdings AB Method and means for treating inflammatory bowel disease
CN101113459A (zh) * 2007-07-16 2008-01-30 东莞太力生物工程有限公司 一种重组复制缺陷型病毒、含有该病毒的药物组合物及其应用
WO2010029317A2 (en) 2008-09-10 2010-03-18 Ibd Column Therapies International Ab Treating inflammatory conditions
WO2014025198A2 (ko) * 2012-08-09 2014-02-13 주식회사 한독 Lfa3 변이체 및 상기 변이체 또는 lfa3 cd2 결합영역과 이에 표적 특이적 폴리펩타이드가 연결된 융합단백질 및 그 용도
EP3972993A1 (en) * 2019-05-21 2022-03-30 Novartis AG Variant cd58 domains and uses thereof

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Also Published As

Publication number Publication date
EA200100304A1 (ru) 2001-10-22
IL141486A (en) 2007-12-03
NO20010956D0 (no) 2001-02-26
WO2000012113A2 (en) 2000-03-09
US20060233796A1 (en) 2006-10-19
EP1109570A2 (en) 2001-06-27
ATE306932T1 (de) 2005-11-15
JP2002523071A (ja) 2002-07-30
IS5848A (is) 2001-02-16
MXPA01002111A (es) 2003-03-27
AU6024499A (en) 2000-03-21
AU764020B2 (en) 2003-08-07
CZ2001725A3 (cs) 2001-08-15
CA2339299C (en) 2009-02-10
DE69927831D1 (de) 2006-03-02
ZA200101213B (en) 2002-02-13
ES2252999T3 (es) 2006-05-16
CN1315866A (zh) 2001-10-03
PL346339A1 (en) 2002-02-11
NO20010956L (no) 2001-04-30
TR200100607T2 (tr) 2001-06-21
HK1038186A1 (en) 2002-03-08
BR9913285A (pt) 2001-05-15
HUP0103563A2 (hu) 2002-01-28
CA2339299A1 (en) 2000-03-09
DK1109570T3 (da) 2006-03-06
NZ510831A (en) 2002-12-20
EE200100123A (et) 2002-06-17
EP1109570B1 (en) 2005-10-19
HUP0103563A3 (en) 2004-04-28
KR20010085687A (ko) 2001-09-07
IL141486A0 (en) 2002-03-10
EA005948B1 (ru) 2005-08-25
CZ298238B6 (cs) 2007-08-01
DE69927831T2 (de) 2006-07-20
WO2000012113A3 (en) 2000-06-29
CN100473417C (zh) 2009-04-01
US20020009446A1 (en) 2002-01-24

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