IS5848A - Aðferð til að stilla T-frumur sem eru svarar og samsetningu þeirra - Google Patents
Aðferð til að stilla T-frumur sem eru svarar og samsetningu þeirraInfo
- Publication number
- IS5848A IS5848A IS5848A IS5848A IS5848A IS 5848 A IS5848 A IS 5848A IS 5848 A IS5848 A IS 5848A IS 5848 A IS5848 A IS 5848A IS 5848 A IS5848 A IS 5848A
- Authority
- IS
- Iceland
- Prior art keywords
- cells
- adjusting
- composition
- lfa
- mammals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70507—CD2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2806—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2824—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD58
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9845698P | 1998-08-31 | 1998-08-31 | |
PCT/US1999/020026 WO2000012113A2 (en) | 1998-08-31 | 1999-08-31 | Method of modulating memory effector t-cells using a cd2-binding agent, and compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
IS5848A true IS5848A (is) | 2001-02-16 |
Family
ID=22269362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS5848A IS5848A (is) | 1998-08-31 | 2001-02-16 | Aðferð til að stilla T-frumur sem eru svarar og samsetningu þeirra |
Country Status (26)
Country | Link |
---|---|
US (2) | US20020009446A1 (is) |
EP (1) | EP1109570B1 (is) |
JP (1) | JP2002523071A (is) |
KR (1) | KR20010085687A (is) |
CN (1) | CN100473417C (is) |
AT (1) | ATE306932T1 (is) |
AU (1) | AU764020B2 (is) |
BR (1) | BR9913285A (is) |
CA (1) | CA2339299C (is) |
CZ (1) | CZ298238B6 (is) |
DE (1) | DE69927831T2 (is) |
DK (1) | DK1109570T3 (is) |
EA (1) | EA005948B1 (is) |
EE (1) | EE200100123A (is) |
ES (1) | ES2252999T3 (is) |
HK (2) | HK1038186A1 (is) |
HU (1) | HUP0103563A3 (is) |
IL (2) | IL141486A0 (is) |
IS (1) | IS5848A (is) |
MX (1) | MXPA01002111A (is) |
NO (1) | NO20010956L (is) |
NZ (1) | NZ510831A (is) |
PL (1) | PL346339A1 (is) |
TR (1) | TR200100607T2 (is) |
WO (1) | WO2000012113A2 (is) |
ZA (1) | ZA200101213B (is) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6764681B2 (en) * | 1991-10-07 | 2004-07-20 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
WO2000012113A2 (en) * | 1998-08-31 | 2000-03-09 | Biogen, Inc. | Method of modulating memory effector t-cells using a cd2-binding agent, and compositions |
ES2571230T3 (es) | 1999-04-09 | 2016-05-24 | Kyowa Hakko Kirin Co Ltd | Procedimiento para controlar la actividad de una molécula inmunofuncional |
US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
US20040170635A1 (en) * | 2001-02-01 | 2004-09-02 | Vaishnaw Akshay K. | Methods for treating or preventing skin disorders using cd2-binding agents |
CA2454618C (en) * | 2001-07-24 | 2012-04-03 | Biogen Idec Ma, Inc. | Methods for treating or preventing sclerotic disorders using cd2-binding agents |
WO2003084569A1 (fr) | 2002-04-09 | 2003-10-16 | Kyowa Hakko Kogyo Co., Ltd. | Medicament contenant une composition anticorps |
WO2005000898A2 (en) * | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
CA2542046A1 (en) * | 2003-10-08 | 2005-04-21 | Kyowa Hakko Kogyo Co., Ltd. | Fused protein composition |
CA2555144A1 (en) * | 2004-02-06 | 2005-08-25 | Astellas Us Llc | Methods of treating skin disorders |
CN1997756A (zh) * | 2004-05-04 | 2007-07-11 | 杰耐萨斯药品公司 | 单倍型标记和利用其确定对于治疗的反应的方法 |
US7662921B2 (en) * | 2004-05-07 | 2010-02-16 | Astellas Us Llc | Methods of treating viral disorders |
WO2006074399A2 (en) * | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
SI2021025T1 (sl) * | 2006-05-12 | 2017-02-28 | Ith Immune Therapy Holdings Ab | Postopek in sredstva za zdravljenje vnetne črevesne bolezni |
CN101113459A (zh) * | 2007-07-16 | 2008-01-30 | 东莞太力生物工程有限公司 | 一种重组复制缺陷型病毒、含有该病毒的药物组合物及其应用 |
KR101703785B1 (ko) | 2008-09-10 | 2017-02-07 | 아이티에이치 임뮨 세라피 홀딩스 에이비 | 염증 증상의 치료 방법 |
WO2014025198A2 (ko) * | 2012-08-09 | 2014-02-13 | 주식회사 한독 | Lfa3 변이체 및 상기 변이체 또는 lfa3 cd2 결합영역과 이에 표적 특이적 폴리펩타이드가 연결된 융합단백질 및 그 용도 |
MX2020010183A (es) * | 2018-03-29 | 2022-11-28 | Pfizer | Variantes y composiciones del lfa3 y sus usos. |
EP3972993A1 (en) * | 2019-05-21 | 2022-03-30 | Novartis AG | Variant cd58 domains and uses thereof |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4579844A (en) * | 1976-05-13 | 1986-04-01 | Johnson & Johnson | Topical anti-inflammatory drug therapy |
US4738927A (en) * | 1982-03-31 | 1988-04-19 | Ajinomoto Co. Inc. | Gene coded for interleukin-2 polypeptide, recombinant DNA carrying the said gene, a living cell line possessing the recombinant DNA, and method for producing interleukin-2 using the said cell |
GB8308235D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4681760A (en) * | 1985-04-17 | 1987-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of conferring immunotolerance to a specific antigen |
NZ215865A (en) * | 1985-04-22 | 1988-10-28 | Commw Serum Lab Commission | Method of determining the active site of a receptor-binding analogue |
US5047336A (en) * | 1985-10-30 | 1991-09-10 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing mullerian inhibiting substance-like polypeptides |
JPH0763830B2 (ja) * | 1985-11-26 | 1995-07-12 | アスモ株式会社 | ダイカスト鋳造金型への離型剤塗布方法 |
US5190859A (en) * | 1987-02-26 | 1993-03-02 | Dana-Farber Cancer Institute, Inc. | Purification of LFA-3 |
US4956281A (en) * | 1987-06-03 | 1990-09-11 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3 |
US5336603A (en) * | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
US5185441A (en) * | 1988-08-26 | 1993-02-09 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing pi-linked lymphocyte function associated antigen-3 |
WO1990008187A1 (en) * | 1989-01-19 | 1990-07-26 | Dana Farber Cancer Institute | Soluble two domain cd2 protein |
US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
US5122514A (en) * | 1990-04-23 | 1992-06-16 | Abbott Laboratories | Psoriasis treatment |
MX9203138A (es) * | 1991-03-12 | 1992-09-01 | Biogen Inc | Dominio de enlace cd2-de antigeno 3 (lfa-3) asociado con funcion linfositos. |
PT503648E (pt) * | 1991-03-12 | 2000-10-31 | Biogen Inc | Dominio do antigenio 3 associado a funcao linfocitica de ligacao as cd2 |
AU660312B2 (en) * | 1991-06-06 | 1995-06-22 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | LFA-3-like protein, derivatives thereof, genes thereof and processes for preparing the same |
US5511563A (en) * | 1991-06-21 | 1996-04-30 | Diamond; Donald A. | Apparatus and method for treating rheumatoid and psoriatic arthritis |
US6764681B2 (en) * | 1991-10-07 | 2004-07-20 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
DE69232295T2 (de) * | 1991-10-07 | 2002-07-18 | Biogen, Inc. | Verfahren zur Verbesserung der Toleranz für Allotransplantaten und Xenotransplantaten durch Verabreichung eines LFA-3- oder CD2-Bindungsproteins |
US6162432A (en) * | 1991-10-07 | 2000-12-19 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
US6270766B1 (en) * | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
US5730979A (en) * | 1993-03-05 | 1998-03-24 | Universite Catholique Delouvain | LO-CD2a antibody and uses thereof for inhibiting T cell activation and proliferation |
US5817311A (en) * | 1993-03-05 | 1998-10-06 | Universite Catholique De Louvain | Methods of inhibiting T-cell medicated immune responses with LO-CD2a-specific antibodies |
US5951983A (en) * | 1993-03-05 | 1999-09-14 | Universite Catholique De Louvain | Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies |
US5795572A (en) * | 1993-05-25 | 1998-08-18 | Bristol-Myers Squibb Company | Monoclonal antibodies and FV specific for CD2 antigen |
CA2210500A1 (en) * | 1995-01-16 | 1996-07-25 | Commonwealth Scientific And Industrial Research Organisation | Therapeutic compound - fatty acid conjugates |
WO2000012113A2 (en) * | 1998-08-31 | 2000-03-09 | Biogen, Inc. | Method of modulating memory effector t-cells using a cd2-binding agent, and compositions |
US6337337B1 (en) * | 1998-09-03 | 2002-01-08 | Carol J. Buck | Methods for treating disorders responsive to DHFR-inhibition |
US20040170635A1 (en) * | 2001-02-01 | 2004-09-02 | Vaishnaw Akshay K. | Methods for treating or preventing skin disorders using cd2-binding agents |
AU2002322478A1 (en) * | 2001-03-02 | 2002-12-16 | Medimmune, Inc. | Methods of administering/dosing cd2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders |
-
1999
- 1999-08-31 WO PCT/US1999/020026 patent/WO2000012113A2/en active IP Right Grant
- 1999-08-31 ES ES99968216T patent/ES2252999T3/es not_active Expired - Lifetime
- 1999-08-31 CA CA002339299A patent/CA2339299C/en not_active Expired - Fee Related
- 1999-08-31 AU AU60244/99A patent/AU764020B2/en not_active Ceased
- 1999-08-31 DK DK99968216T patent/DK1109570T3/da active
- 1999-08-31 BR BR9913285-0A patent/BR9913285A/pt not_active Application Discontinuation
- 1999-08-31 IL IL14148699A patent/IL141486A0/xx active IP Right Grant
- 1999-08-31 EP EP99968216A patent/EP1109570B1/en not_active Expired - Lifetime
- 1999-08-31 NZ NZ510831A patent/NZ510831A/xx unknown
- 1999-08-31 AT AT99968216T patent/ATE306932T1/de not_active IP Right Cessation
- 1999-08-31 EE EEP200100123A patent/EE200100123A/xx unknown
- 1999-08-31 KR KR1020017002566A patent/KR20010085687A/ko not_active Application Discontinuation
- 1999-08-31 JP JP2000567227A patent/JP2002523071A/ja active Pending
- 1999-08-31 MX MXPA01002111A patent/MXPA01002111A/es active IP Right Grant
- 1999-08-31 CN CNB998103128A patent/CN100473417C/zh not_active Expired - Fee Related
- 1999-08-31 HU HU0103563A patent/HUP0103563A3/hu unknown
- 1999-08-31 EA EA200100304A patent/EA005948B1/ru not_active IP Right Cessation
- 1999-08-31 DE DE69927831T patent/DE69927831T2/de not_active Expired - Fee Related
- 1999-08-31 CZ CZ20010725A patent/CZ298238B6/cs not_active IP Right Cessation
- 1999-08-31 TR TR2001/00607T patent/TR200100607T2/xx unknown
- 1999-08-31 PL PL99346339A patent/PL346339A1/xx not_active Application Discontinuation
-
2001
- 2001-02-13 ZA ZA200101213A patent/ZA200101213B/en unknown
- 2001-02-16 IS IS5848A patent/IS5848A/is unknown
- 2001-02-18 IL IL141486A patent/IL141486A/en not_active IP Right Cessation
- 2001-02-26 NO NO20010956A patent/NO20010956L/no not_active Application Discontinuation
- 2001-02-27 US US09/796,033 patent/US20020009446A1/en not_active Abandoned
- 2001-12-19 HK HK01108882A patent/HK1038186A1/xx not_active IP Right Cessation
-
2002
- 2002-02-26 HK HK02101435.9A patent/HK1040186A1/zh unknown
-
2006
- 2006-04-06 US US11/398,908 patent/US20060233796A1/en not_active Abandoned
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