HK1015708A1 - Use of muteins of wild-type cytokines as immunogens. - Google Patents

Use of muteins of wild-type cytokines as immunogens.

Info

Publication number
HK1015708A1
HK1015708A1 HK99100962A HK99100962A HK1015708A1 HK 1015708 A1 HK1015708 A1 HK 1015708A1 HK 99100962 A HK99100962 A HK 99100962A HK 99100962 A HK99100962 A HK 99100962A HK 1015708 A1 HK1015708 A1 HK 1015708A1
Authority
HK
Hong Kong
Prior art keywords
cytokines
muteins
immunogens
wild
type cytokines
Prior art date
Application number
HK99100962A
Other languages
English (en)
Inventor
Gennaro Ciliberto
Rocco Savino
Riccardo Cortese
Original Assignee
Istituto Di Recerche Di Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Di Recerche Di Biolog filed Critical Istituto Di Recerche Di Biolog
Publication of HK1015708A1 publication Critical patent/HK1015708A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Noise Elimination (AREA)
  • Medicinal Preparation (AREA)
HK99100962A 1995-09-01 1999-03-09 Use of muteins of wild-type cytokines as immunogens. HK1015708A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95RM000589A IT1277926B1 (it) 1995-09-01 1995-09-01 Uso di muteine di citochine naturali come immunogeni per la preparazione di composizioni farmaceutiche per curare o prevenire
PCT/IT1996/000164 WO1997009064A1 (en) 1995-09-01 1996-08-22 Use of muteins of wild-type cytokines as immunogens

Publications (1)

Publication Number Publication Date
HK1015708A1 true HK1015708A1 (en) 1999-10-22

Family

ID=11403544

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100962A HK1015708A1 (en) 1995-09-01 1999-03-09 Use of muteins of wild-type cytokines as immunogens.

Country Status (17)

Country Link
US (1) US6706261B1 (ja)
EP (1) EP0858345B1 (ja)
JP (1) JP3157837B2 (ja)
KR (1) KR100279539B1 (ja)
CN (1) CN1138562C (ja)
AT (1) ATE226446T1 (ja)
AU (1) AU703300B2 (ja)
CA (1) CA2229045C (ja)
DE (1) DE69624498T2 (ja)
DK (1) DK0858345T3 (ja)
ES (1) ES2183007T3 (ja)
HK (1) HK1015708A1 (ja)
IT (1) IT1277926B1 (ja)
MX (1) MX9801550A (ja)
PT (1) PT858345E (ja)
RU (1) RU2182014C2 (ja)
WO (1) WO1997009064A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR025984A1 (es) * 1999-10-07 2002-12-26 Maxygen Aps Polipeptidos oligomericos de cadena simple
FR2812813B1 (fr) * 2000-08-09 2004-11-26 Neovacs Utilisation d'immunogenes pour traiter ou prevenir au sein des tumeurs malignes les dereglements immunitaires induits par des facteurs extracellulaires
IL161672A0 (en) * 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
FR2978964B1 (fr) 2011-08-09 2015-02-20 Conservatoire Nat Arts Composition vaccinale anti-il-6
WO2015024148A1 (zh) * 2013-08-23 2015-02-26 中国科学院微生物研究所 异源动物细胞因子突变体疫苗

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2677654B1 (fr) 1991-06-17 1995-11-17 Pasteur Merieux Serums Vacc Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv.
US5338833A (en) * 1992-07-23 1994-08-16 The University Of North Carolina At Chapel Hill Carboxy terminal IL-6 muteins
IT1263022B (it) * 1992-11-06 1996-07-23 Angeletti P Ist Richerche Bio Interleuchina-6 mutante con attivita' biologica migliorata rispetto all'interleuchina-6 selvatica.
IT1261787B (it) * 1993-06-23 1996-06-03 Angeletti P Ist Richerche Bio Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130.
WO1997010338A1 (en) 1995-09-12 1997-03-20 Chiron Corporation Improved interleukin-6 receptor antagonist

Also Published As

Publication number Publication date
WO1997009064A1 (en) 1997-03-13
AU703300B2 (en) 1999-03-25
DE69624498T2 (de) 2003-06-18
EP0858345B1 (en) 2002-10-23
CN1138562C (zh) 2004-02-18
CA2229045A1 (en) 1997-03-13
JPH10511111A (ja) 1998-10-27
KR100279539B1 (ko) 2001-02-01
EP0858345A1 (en) 1998-08-19
PT858345E (pt) 2003-02-28
ITRM950589A0 (it) 1995-09-01
CA2229045C (en) 2005-10-25
DK0858345T3 (da) 2003-02-24
RU2182014C2 (ru) 2002-05-10
DE69624498D1 (de) 2002-11-28
IT1277926B1 (it) 1997-11-12
ITRM950589A1 (it) 1997-03-01
KR19990044321A (ko) 1999-06-25
ES2183007T3 (es) 2003-03-16
ATE226446T1 (de) 2002-11-15
US6706261B1 (en) 2004-03-16
AU6942896A (en) 1997-03-27
MX9801550A (es) 1998-05-31
CN1198098A (zh) 1998-11-04
JP3157837B2 (ja) 2001-04-16

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090822