PT758241E - Utilizacao de certos derivados de acido metanobisfosfonico para impedir o desprendimento de proteses e a migracao de proteses - Google Patents

Utilizacao de certos derivados de acido metanobisfosfonico para impedir o desprendimento de proteses e a migracao de proteses

Info

Publication number
PT758241E
PT758241E PT95914495T PT95914495T PT758241E PT 758241 E PT758241 E PT 758241E PT 95914495 T PT95914495 T PT 95914495T PT 95914495 T PT95914495 T PT 95914495T PT 758241 E PT758241 E PT 758241E
Authority
PT
Portugal
Prior art keywords
acid derivatives
certain
pct
methanbosphosphonic
proteses
Prior art date
Application number
PT95914495T
Other languages
English (en)
Inventor
Allen E Goodship
John Kenwright
Jonathan Green
Original Assignee
Novartis Erfind Verwalt Gmbh
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfind Verwalt Gmbh, Novartis Ag filed Critical Novartis Erfind Verwalt Gmbh
Publication of PT758241E publication Critical patent/PT758241E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT95914495T 1994-05-04 1995-04-24 Utilizacao de certos derivados de acido metanobisfosfonico para impedir o desprendimento de proteses e a migracao de proteses PT758241E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408775A GB9408775D0 (en) 1994-05-04 1994-05-04 Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration

Publications (1)

Publication Number Publication Date
PT758241E true PT758241E (pt) 2002-10-31

Family

ID=10754497

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95914495T PT758241E (pt) 1994-05-04 1995-04-24 Utilizacao de certos derivados de acido metanobisfosfonico para impedir o desprendimento de proteses e a migracao de proteses

Country Status (18)

Country Link
US (1) US5965547A (pt)
EP (1) EP0758241B1 (pt)
JP (1) JPH09512816A (pt)
AT (1) ATE218350T1 (pt)
AU (1) AU693541B2 (pt)
DE (1) DE69526937T2 (pt)
DK (1) DK0758241T3 (pt)
ES (1) ES2177642T3 (pt)
FI (1) FI118590B (pt)
GB (1) GB9408775D0 (pt)
HU (1) HUT74984A (pt)
IL (1) IL113566A (pt)
NO (1) NO310057B1 (pt)
NZ (1) NZ283430A (pt)
PT (1) PT758241E (pt)
TW (1) TW458779B (pt)
WO (1) WO1995030421A1 (pt)
ZA (1) ZA953537B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
GB2336311A (en) * 1998-04-15 1999-10-20 Merck & Co Inc Bisphosphonate Dosing Regimen
US6137012A (en) 1998-10-13 2000-10-24 E. I. Du Pont De Nemours And Company Phosphole and diphosphole ligands for catalysis
DE69927048T2 (de) 1998-12-04 2006-06-08 Roche Diagnostics Gmbh Ibandroinsäure zur förderung der osseointegration der endoprothesen
EP1150684A4 (en) * 1999-02-09 2005-06-15 Sloan Kettering Institutefor C BONE CEMENT ANTI-RESORPTION AND ALLOGENOUS BONE IMPLANTS, AUTOGRAFTS AND XENOGRAFTS
US6692758B1 (en) * 1999-08-02 2004-02-17 Toray Industries, Inc. Insertion stabilizers for implants
AUPQ232599A0 (en) * 1999-08-19 1999-09-09 Royal Alexandra Hospital For Children, The Drug for treating fractures
SI1296689T1 (sl) 2000-06-20 2006-08-31 Novartis Ag Nacin dajanja pacientu bisfosfonatov
JP4722375B2 (ja) * 2000-06-20 2011-07-13 ノバルティス アーゲー ビホスホネートの投与法
WO2002004038A1 (en) * 2000-07-12 2002-01-17 Hopital Orthopedique De La Suisse Romande Active biocoating for bone implant
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
CA2372450A1 (en) * 2001-05-10 2001-09-19 Pharmaceutical Partners Of Canada Inc. Liquid injectable formulation of disodium pamidronate
PL399493A1 (pl) * 2002-05-10 2012-11-05 F. Hoffmann-La Roche Ag Kwasy bisfosfonowe do leczenia i profilaktyki osteoporozy
AU2003270196A1 (en) * 2002-09-16 2004-04-30 Kenneth W. Lyles Method for preventing or reducing secondary fractures after hip fracture
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation
AU2007321108A1 (en) * 2006-11-17 2008-05-22 Besins Healthcare Pharmaceutical compositions comprising a bisphosphonate compound
EP1958649A1 (en) * 2007-02-14 2008-08-20 Graftys Injectable calcium-phosphate cement releasing a bone resorption inhibitor
EP2136814A4 (en) * 2007-03-21 2012-05-30 Univ Duke MEDICAL KITS AND FORMULATIONS FOR PREVENTING, TREATING OR REDUCING SECONDARY FRACTURES FROM A PREVIOUS FRACTURE
WO2008152518A2 (en) * 2007-05-16 2008-12-18 Actavis Group Ptc Ehf Process for the preparation of risedronic acid or risedronate sodium
WO2011028737A2 (en) 2009-09-01 2011-03-10 Duke University Bisphosphonate compositions and methods for treating heart failure
US8882740B2 (en) * 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone
WO2013074587A1 (en) 2011-11-16 2013-05-23 Duke University Bishophonate compositions and methods for treating and/or reducing cardiac dysfunction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
DE10199052I1 (de) * 1986-11-21 2002-01-10 Novartis Ag Neue substituierte Alkandiphosphonsaeuren
JPH05163150A (ja) * 1991-05-13 1993-06-29 E R Squibb & Sons Inc アテローム性動脈硬化症の抑制・治療剤
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices

Also Published As

Publication number Publication date
WO1995030421A1 (en) 1995-11-16
HUT74984A (en) 1997-03-28
FI964332A0 (fi) 1996-10-28
IL113566A (en) 2002-05-23
NO964486D0 (no) 1996-10-22
EP0758241A1 (en) 1997-02-19
AU693541B2 (en) 1998-07-02
EP0758241B1 (en) 2002-06-05
US5965547A (en) 1999-10-12
DE69526937T2 (de) 2003-01-02
IL113566A0 (en) 1995-08-31
NO310057B1 (no) 2001-05-14
ATE218350T1 (de) 2002-06-15
ZA953537B (en) 1995-11-06
DK0758241T3 (da) 2002-09-23
DE69526937D1 (de) 2002-07-11
NZ283430A (en) 2000-06-23
AU2146695A (en) 1995-11-29
ES2177642T3 (es) 2002-12-16
NO964486L (no) 1996-10-22
FI964332A (fi) 1996-10-28
TW458779B (en) 2001-10-11
FI118590B (fi) 2008-01-15
GB9408775D0 (en) 1994-06-22
HU9603042D0 (en) 1997-01-28
JPH09512816A (ja) 1997-12-22

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