DE69624498D1 - Muteine von wildtyp-cytokinen und ihre verwendung als immunogene - Google Patents
Muteine von wildtyp-cytokinen und ihre verwendung als immunogeneInfo
- Publication number
- DE69624498D1 DE69624498D1 DE69624498T DE69624498T DE69624498D1 DE 69624498 D1 DE69624498 D1 DE 69624498D1 DE 69624498 T DE69624498 T DE 69624498T DE 69624498 T DE69624498 T DE 69624498T DE 69624498 D1 DE69624498 D1 DE 69624498D1
- Authority
- DE
- Germany
- Prior art keywords
- cytokines
- muteine
- immunogenes
- wild
- type cytokines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Noise Elimination (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95RM000589A IT1277926B1 (it) | 1995-09-01 | 1995-09-01 | Uso di muteine di citochine naturali come immunogeni per la preparazione di composizioni farmaceutiche per curare o prevenire |
PCT/IT1996/000164 WO1997009064A1 (en) | 1995-09-01 | 1996-08-22 | Use of muteins of wild-type cytokines as immunogens |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69624498D1 true DE69624498D1 (de) | 2002-11-28 |
DE69624498T2 DE69624498T2 (de) | 2003-06-18 |
Family
ID=11403544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69624498T Expired - Fee Related DE69624498T2 (de) | 1995-09-01 | 1996-08-22 | Muteine von wildtyp-cytokinen und ihre verwendung als immunogene |
Country Status (17)
Country | Link |
---|---|
US (1) | US6706261B1 (de) |
EP (1) | EP0858345B1 (de) |
JP (1) | JP3157837B2 (de) |
KR (1) | KR100279539B1 (de) |
CN (1) | CN1138562C (de) |
AT (1) | ATE226446T1 (de) |
AU (1) | AU703300B2 (de) |
CA (1) | CA2229045C (de) |
DE (1) | DE69624498T2 (de) |
DK (1) | DK0858345T3 (de) |
ES (1) | ES2183007T3 (de) |
HK (1) | HK1015708A1 (de) |
IT (1) | IT1277926B1 (de) |
MX (1) | MX9801550A (de) |
PT (1) | PT858345E (de) |
RU (1) | RU2182014C2 (de) |
WO (1) | WO1997009064A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR025984A1 (es) * | 1999-10-07 | 2002-12-26 | Maxygen Aps | Polipeptidos oligomericos de cadena simple |
FR2812813B1 (fr) * | 2000-08-09 | 2004-11-26 | Neovacs | Utilisation d'immunogenes pour traiter ou prevenir au sein des tumeurs malignes les dereglements immunitaires induits par des facteurs extracellulaires |
IL161672A0 (en) * | 2004-04-29 | 2004-09-27 | Yeda Res & Dev | Compositions and methods for therapy of chemotherapy-induced neuropathy |
FR2978964B1 (fr) | 2011-08-09 | 2015-02-20 | Conservatoire Nat Arts | Composition vaccinale anti-il-6 |
WO2015024148A1 (zh) * | 2013-08-23 | 2015-02-26 | 中国科学院微生物研究所 | 异源动物细胞因子突变体疫苗 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2677654B1 (fr) | 1991-06-17 | 1995-11-17 | Pasteur Merieux Serums Vacc | Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv. |
US5338833A (en) * | 1992-07-23 | 1994-08-16 | The University Of North Carolina At Chapel Hill | Carboxy terminal IL-6 muteins |
IT1263022B (it) * | 1992-11-06 | 1996-07-23 | Angeletti P Ist Richerche Bio | Interleuchina-6 mutante con attivita' biologica migliorata rispetto all'interleuchina-6 selvatica. |
IT1261787B (it) * | 1993-06-23 | 1996-06-03 | Angeletti P Ist Richerche Bio | Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130. |
WO1997010338A1 (en) | 1995-09-12 | 1997-03-20 | Chiron Corporation | Improved interleukin-6 receptor antagonist |
-
1995
- 1995-09-01 IT IT95RM000589A patent/IT1277926B1/it active IP Right Grant
-
1996
- 1996-08-22 CA CA002229045A patent/CA2229045C/en not_active Expired - Fee Related
- 1996-08-22 KR KR1019980701561A patent/KR100279539B1/ko not_active IP Right Cessation
- 1996-08-22 ES ES96930345T patent/ES2183007T3/es not_active Expired - Lifetime
- 1996-08-22 DK DK96930345T patent/DK0858345T3/da active
- 1996-08-22 RU RU98105679/14A patent/RU2182014C2/ru not_active IP Right Cessation
- 1996-08-22 WO PCT/IT1996/000164 patent/WO1997009064A1/en active IP Right Grant
- 1996-08-22 AU AU69428/96A patent/AU703300B2/en not_active Ceased
- 1996-08-22 JP JP51104897A patent/JP3157837B2/ja not_active Expired - Fee Related
- 1996-08-22 AT AT96930345T patent/ATE226446T1/de not_active IP Right Cessation
- 1996-08-22 EP EP96930345A patent/EP0858345B1/de not_active Expired - Lifetime
- 1996-08-22 PT PT96930345T patent/PT858345E/pt unknown
- 1996-08-22 MX MX9801550A patent/MX9801550A/es not_active IP Right Cessation
- 1996-08-22 CN CNB961972955A patent/CN1138562C/zh not_active Expired - Fee Related
- 1996-08-22 DE DE69624498T patent/DE69624498T2/de not_active Expired - Fee Related
-
1999
- 1999-03-09 HK HK99100962A patent/HK1015708A1/xx not_active IP Right Cessation
-
2000
- 2000-04-27 US US09/559,950 patent/US6706261B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE226446T1 (de) | 2002-11-15 |
ITRM950589A1 (it) | 1997-03-01 |
PT858345E (pt) | 2003-02-28 |
AU6942896A (en) | 1997-03-27 |
ES2183007T3 (es) | 2003-03-16 |
HK1015708A1 (en) | 1999-10-22 |
KR19990044321A (ko) | 1999-06-25 |
US6706261B1 (en) | 2004-03-16 |
JP3157837B2 (ja) | 2001-04-16 |
ITRM950589A0 (it) | 1995-09-01 |
CN1138562C (zh) | 2004-02-18 |
JPH10511111A (ja) | 1998-10-27 |
CA2229045A1 (en) | 1997-03-13 |
MX9801550A (es) | 1998-05-31 |
EP0858345A1 (de) | 1998-08-19 |
DE69624498T2 (de) | 2003-06-18 |
CA2229045C (en) | 2005-10-25 |
AU703300B2 (en) | 1999-03-25 |
DK0858345T3 (da) | 2003-02-24 |
WO1997009064A1 (en) | 1997-03-13 |
KR100279539B1 (ko) | 2001-02-01 |
CN1198098A (zh) | 1998-11-04 |
IT1277926B1 (it) | 1997-11-12 |
RU2182014C2 (ru) | 2002-05-10 |
EP0858345B1 (de) | 2002-10-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0591281T3 (da) | Immunogene forbindelser, der især har anticytokinvirkning, fremstillingsfremgangsmåde, farmaceutiske præparater samt kits, | |
ATE466085T1 (de) | Protease-resistente modifizierte interferon alpha polypeptide | |
EE9900481A (et) | Väikesed molekulid, mida kasutatakse põletikuliste haiguste raviks | |
BRPI0508455A (pt) | muteìnas de interleucina-2 combinatórias | |
ATE311451T1 (de) | Muteine von menschlichem mit neutrophiler gelatinase-asoziiertem lipocalin und damit verwandte proteine | |
DE59010367D1 (de) | Muteine des menschlichen Erythropoetins, ihre Herstellung und ihre Verwendung | |
ES2149971T3 (es) | Derivados 5-sustituidos del acido micofenolico. | |
ATE414104T1 (de) | Fragmente des menschlichen choriogonadotropin (hcg) als immunregulator | |
EA200000911A1 (ru) | Новые кристаллические формы антивирусного соединения бензимидазола | |
DE69708121D1 (de) | Halogenid-enthaltende insulinzubereitungen | |
Habibi et al. | Cytokine gene expression in healing and non‐healing cases of cutaneous leishmaniasis in response to in vitro stimulation with recombinant gp63 using semi‐quantitative RT–PCR | |
DE60040740D1 (de) | VERWENDUNG OF INTERLEUkIN-1 MUTEIN ALS IMPFSTOFFADJUVANS | |
DE59610632D1 (de) | Varianten des humanen rekombinanten interferon-gamma (rhu-ifn-gamma) mit erhöhter thermischer stabilität | |
NO984244D0 (no) | Vaksinesammensetninger og fremgangsmÕter som er nyttige i Õ indusere immunbeskyttelse mot artritogene peptider som er involvert i patogenese av reumatoid artritt | |
ATE249835T1 (de) | Immunoregulator | |
DE69624498D1 (de) | Muteine von wildtyp-cytokinen und ihre verwendung als immunogene | |
BR0207528A (pt) | Anticorpo, composição farmacêutica, e, usos de uma quantidade efetiva de um agente, de uma quantidade terapeuticamente efetiva de um anticorpo para il-22, de uma quantidade imunogênica do antìgeno e uma quantidade aumentadora de imunogenicidade de il-22 em combinação, de uma quantidade efetiva do anticorpo ou fragmento do mesmo e de uma quantidade suficiente de anticorpo ou fragmento ligado a antìgeno do mesmo | |
DE69736276D1 (de) | Menschliche dnase resistent gegen actininhibitoren | |
DK1290160T3 (da) | Humane Pellino-polypeptider | |
DK0946730T3 (da) | Mutanter af streptokok-toksin C og fremgangsmåder til anvendelse | |
DE69737032D1 (de) | Mutanten von streptococcaltoxinen und vefahren zu deren anwendung | |
YU39396A (sh) | Upotreba izolovanog prirodnog proteina gojaznosti za pripremu leka i njegova farmaceutska formulacija | |
DE69637435D1 (de) | Saponin-zusammensetzungen und deren verwendung | |
DE69003216D1 (de) | Verwendung von somatostatin. | |
BR9812489A (pt) | Uso de 6,7-substituìdas-2-aminotetralinas adequadas para a preparação de uma composição farmacêutica para o tratamento terapêutico de patologias inflamatórias e/ou autoimunes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |