HK1015366A1 - Indolealkyl derivatives of benzodioxanmethylamine as 5-ht1a receptor ligands - Google Patents
Indolealkyl derivatives of benzodioxanmethylamine as 5-ht1a receptor ligandsInfo
- Publication number
- HK1015366A1 HK1015366A1 HK99100444A HK99100444A HK1015366A1 HK 1015366 A1 HK1015366 A1 HK 1015366A1 HK 99100444 A HK99100444 A HK 99100444A HK 99100444 A HK99100444 A HK 99100444A HK 1015366 A1 HK1015366 A1 HK 1015366A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- benzodioxanmethylamine
- receptor ligands
- ht1a receptor
- indolealkyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US728495P | 1995-11-06 | 1995-11-06 | |
PCT/US1996/017275 WO1997017343A1 (fr) | 1995-11-06 | 1996-10-29 | Derives indolealkyle de benzodioxanmethylamine utiles en tant que ligands du recepteur 5-ht1a |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1015366A1 true HK1015366A1 (en) | 1999-10-15 |
Family
ID=21725271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99100444A HK1015366A1 (en) | 1995-11-06 | 1999-02-02 | Indolealkyl derivatives of benzodioxanmethylamine as 5-ht1a receptor ligands |
Country Status (21)
Country | Link |
---|---|
US (1) | US5750724A (fr) |
EP (1) | EP0861248B1 (fr) |
JP (1) | JP2000500136A (fr) |
KR (1) | KR19990067303A (fr) |
CN (1) | CN1074414C (fr) |
AR (1) | AR004229A1 (fr) |
AT (1) | ATE210659T1 (fr) |
BR (1) | BR9611406A (fr) |
CA (1) | CA2236678A1 (fr) |
DE (1) | DE69617995T2 (fr) |
DK (1) | DK0861248T3 (fr) |
ES (1) | ES2166470T3 (fr) |
HK (1) | HK1015366A1 (fr) |
HU (1) | HUP9902091A3 (fr) |
IL (1) | IL124095A (fr) |
MX (1) | MX9803455A (fr) |
NZ (1) | NZ321821A (fr) |
PT (1) | PT861248E (fr) |
TW (1) | TW498075B (fr) |
WO (1) | WO1997017343A1 (fr) |
ZA (1) | ZA969221B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6231833B1 (en) | 1999-08-05 | 2001-05-15 | Pfizer Inc | 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors |
US6121307A (en) | 1998-04-08 | 2000-09-19 | American Home Products Corp. | N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
WO2000069424A2 (fr) * | 1999-05-12 | 2000-11-23 | Solvay Pharmaceuticals B.V. | Methode de traitement de troubles psychotiques |
TR200200460T2 (tr) | 1999-08-23 | 2002-06-21 | Solvay Pharmaceuticals B.V. | Yeni fenilpiperazinler |
FR2799463B1 (fr) * | 1999-10-12 | 2004-04-16 | Adir | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent |
AR032712A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
AU2002258971A1 (en) | 2001-04-24 | 2002-11-05 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan |
US7041683B2 (en) * | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
US6656951B2 (en) | 2001-04-24 | 2003-12-02 | Wyeth | 8-aza-bicyclo[3.2.1]octan-3-ol derivatives of 2,3-dihydro-1,4-benzodioxan as 5-HT1A antagonists |
US6656950B2 (en) | 2001-04-25 | 2003-12-02 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine |
US8106074B2 (en) | 2001-07-13 | 2012-01-31 | Pierre Fabre Medicament | Pyridin-2-yl-methylamine derivatives for treating opiate dependence |
US6667322B2 (en) | 2001-10-05 | 2003-12-23 | Wyeth | Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole |
US6800637B2 (en) * | 2002-09-12 | 2004-10-05 | Wyeth | Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines |
US6911445B2 (en) | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
US7227023B2 (en) * | 2003-04-30 | 2007-06-05 | Wyeth | Quinoline 3-amino chroman derivatives |
BRPI0608353A2 (pt) * | 2005-02-17 | 2009-12-01 | Wyeth Corp | derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos |
DK2271634T3 (da) | 2008-04-29 | 2014-05-05 | Integrative Res Lab Sweden Ab | Modulatorer af dopamin-neurotransmission |
US20110105462A1 (en) * | 2008-04-29 | 2011-05-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
EP2271638B1 (fr) | 2008-04-29 | 2011-08-31 | NSAB, Filial af NeuroSearch Sweden AB, Sverige | Modulateurs de la neurotransmission de la dopamine |
CN103965186B (zh) * | 2013-01-25 | 2016-05-18 | 江苏恩华药业股份有限公司 | 苯并二噁烷-苯并噁(噻)唑哌啶衍生物及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE635203A (fr) * | 1962-07-20 | |||
JPS58219114A (ja) * | 1982-06-15 | 1983-12-20 | Mitsubishi Chem Ind Ltd | 血圧降下剤 |
DE3419935A1 (de) * | 1984-05-28 | 1985-11-28 | Merck Patent Gmbh, 6100 Darmstadt | Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks |
US4910302A (en) * | 1988-12-19 | 1990-03-20 | American Home Products Corporation | Psychotropic polycyclic imides |
CA2043709C (fr) * | 1990-06-29 | 2002-01-22 | David W. Smith | Derives pour combattre la migraine d'alcoxypirimidine |
DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
FR2707294B1 (fr) * | 1993-07-06 | 1995-09-29 | Pf Medicament | Nouveaux dérivés de la 3,5-dioxo-(2H,4H)-1,2,4-triazine, leur préparation et leur application en thérapeutique humaine. |
DE19512639A1 (de) * | 1995-04-05 | 1996-10-10 | Merck Patent Gmbh | Benzonitrile und -fluoride |
-
1996
- 1996-10-24 AR ARP960104894A patent/AR004229A1/es active IP Right Grant
- 1996-10-29 ES ES96937782T patent/ES2166470T3/es not_active Expired - Lifetime
- 1996-10-29 BR BR9611406A patent/BR9611406A/pt not_active Application Discontinuation
- 1996-10-29 AT AT96937782T patent/ATE210659T1/de not_active IP Right Cessation
- 1996-10-29 KR KR1019980703286A patent/KR19990067303A/ko active IP Right Grant
- 1996-10-29 CN CN96199286A patent/CN1074414C/zh not_active Expired - Fee Related
- 1996-10-29 EP EP96937782A patent/EP0861248B1/fr not_active Expired - Lifetime
- 1996-10-29 DE DE69617995T patent/DE69617995T2/de not_active Expired - Fee Related
- 1996-10-29 IL IL12409596A patent/IL124095A/en not_active IP Right Cessation
- 1996-10-29 JP JP9518222A patent/JP2000500136A/ja not_active Withdrawn
- 1996-10-29 NZ NZ321821A patent/NZ321821A/xx unknown
- 1996-10-29 CA CA002236678A patent/CA2236678A1/fr not_active Abandoned
- 1996-10-29 DK DK96937782T patent/DK0861248T3/da active
- 1996-10-29 PT PT96937782T patent/PT861248E/pt unknown
- 1996-10-29 WO PCT/US1996/017275 patent/WO1997017343A1/fr active IP Right Grant
- 1996-10-29 HU HU9902091A patent/HUP9902091A3/hu unknown
- 1996-10-30 US US08/739,912 patent/US5750724A/en not_active Expired - Lifetime
- 1996-11-01 ZA ZA9609221A patent/ZA969221B/xx unknown
- 1996-11-05 TW TW085113500A patent/TW498075B/zh active
-
1998
- 1998-04-30 MX MX9803455A patent/MX9803455A/es not_active IP Right Cessation
-
1999
- 1999-02-02 HK HK99100444A patent/HK1015366A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW498075B (en) | 2002-08-11 |
AU7524596A (en) | 1997-05-29 |
NZ321821A (en) | 1999-07-29 |
CN1205700A (zh) | 1999-01-20 |
KR19990067303A (ko) | 1999-08-16 |
ZA969221B (en) | 1998-05-04 |
CA2236678A1 (fr) | 1997-05-15 |
IL124095A (en) | 2001-10-31 |
CN1074414C (zh) | 2001-11-07 |
DK0861248T3 (da) | 2002-04-08 |
AU704216B2 (en) | 1999-04-15 |
JP2000500136A (ja) | 2000-01-11 |
AR004229A1 (es) | 1998-11-04 |
WO1997017343A1 (fr) | 1997-05-15 |
PT861248E (pt) | 2002-05-31 |
EP0861248B1 (fr) | 2001-12-12 |
DE69617995D1 (de) | 2002-01-24 |
HUP9902091A3 (en) | 2000-03-28 |
DE69617995T2 (de) | 2002-05-16 |
HUP9902091A2 (hu) | 2000-02-28 |
US5750724A (en) | 1998-05-12 |
BR9611406A (pt) | 1999-01-05 |
ES2166470T3 (es) | 2002-04-16 |
ATE210659T1 (de) | 2001-12-15 |
EP0861248A1 (fr) | 1998-09-02 |
MX9803455A (es) | 1998-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20051029 |