HK1015351A1 - Substituted amino compounds and their use as analgesic active substances - Google Patents

Substituted amino compounds and their use as analgesic active substances

Info

Publication number
HK1015351A1
HK1015351A1 HK99100283A HK99100283A HK1015351A1 HK 1015351 A1 HK1015351 A1 HK 1015351A1 HK 99100283 A HK99100283 A HK 99100283A HK 99100283 A HK99100283 A HK 99100283A HK 1015351 A1 HK1015351 A1 HK 1015351A1
Authority
HK
Hong Kong
Prior art keywords
active substances
substituted amino
amino compounds
analgesic active
analgesic
Prior art date
Application number
HK99100283A
Other languages
English (en)
Inventor
Oswald Zimmer
Wolfgang Strassburger
Werner Alfred
Helmut Heinrich Buschmann
Werner Englberger
Elmar Josef Friderichs
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of HK1015351A1 publication Critical patent/HK1015351A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/28Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by unsaturated carbon chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK99100283A 1997-03-14 1999-01-21 Substituted amino compounds and their use as analgesic active substances HK1015351A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19710628 1997-03-14

Publications (1)

Publication Number Publication Date
HK1015351A1 true HK1015351A1 (en) 1999-10-15

Family

ID=7823396

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100283A HK1015351A1 (en) 1997-03-14 1999-01-21 Substituted amino compounds and their use as analgesic active substances

Country Status (29)

Country Link
US (1) US6022895A (es)
EP (1) EP0864559B1 (es)
JP (1) JP4132189B2 (es)
KR (1) KR100579428B1 (es)
CN (1) CN1243721C (es)
AR (1) AR010129A1 (es)
AT (1) ATE218534T1 (es)
AU (1) AU728501B2 (es)
CA (1) CA2231975C (es)
CO (1) CO4940510A1 (es)
CZ (1) CZ295522B6 (es)
DE (2) DE19805370A1 (es)
DK (1) DK0864559T3 (es)
ES (1) ES2178055T3 (es)
HK (1) HK1015351A1 (es)
HU (1) HU226060B1 (es)
IL (1) IL123647A (es)
MY (1) MY118828A (es)
NO (1) NO311128B1 (es)
NZ (1) NZ329951A (es)
PE (1) PE59899A1 (es)
PL (1) PL191727B1 (es)
PT (1) PT864559E (es)
RU (1) RU2197474C2 (es)
SI (1) SI0864559T1 (es)
SK (1) SK284279B6 (es)
UA (1) UA56997C2 (es)
UY (1) UY24919A1 (es)
ZA (1) ZA982157B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8164251B2 (en) 2005-11-18 2012-04-24 Idemitsu Kosan Co., Ltd. Aromatic amine derivatives and organic electroluminescence devices using the same

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate
DE19963179B4 (de) 1999-12-27 2009-02-05 Grünenthal GmbH Substituierte 1- und 2-Naphthol-Mannichbasen
DE10033459A1 (de) * 2000-07-10 2002-01-24 Gruenenthal Gmbh Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel
AU2002346994B2 (en) 2001-10-15 2007-09-06 Janssen Pharmaceutica N.V. Novel substituted 4-phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives and their use as selective non-peptide delta opioid agonists
DE10206405A1 (de) * 2002-02-14 2003-08-28 Gruenenthal Gmbh Synthese von substituierten Carbamidestern
DE10206403A1 (de) * 2002-02-14 2003-08-28 Gruenenthal Gmbh Synthese von Beta-Aminoketonen
CL2004000754A1 (es) * 2003-04-11 2005-02-25 Janssen Pharmaceutica Nv Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central.
DE10341534A1 (de) * 2003-09-09 2005-03-31 Bayer Chemicals Ag Difluoralkylaromaten
CN100549004C (zh) 2003-10-01 2009-10-14 阿得罗公司 螺环杂环衍生物及其应用方法
DE102004030099A1 (de) * 2004-06-22 2006-01-12 Grünenthal GmbH Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren
WO2006023757A2 (en) * 2004-08-19 2006-03-02 University Of Virginia Patent Foundation Novel tricyclic, bicyclic, monocyclic, and acyclic amines as potent sodium channel blocking agents
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
TWI401237B (zh) * 2006-07-24 2013-07-11 3-〔(1r,2r)-3-(二甲基氨基)-1-乙基-2-甲基丙基〕酚之製備
AU2007294968A1 (en) * 2006-09-12 2008-03-20 Adolor Corporation Use of N-containing spirocompounds for the enhancement of cognitive function
JP2010519206A (ja) * 2007-02-16 2010-06-03 シンタ ファーマシューティカルズ コーポレーション 炎症及び免疫関連使用のための置換縮合環化合物
WO2012100423A1 (en) * 2011-01-27 2012-08-02 Eli Lilly And Company Analgesic compounds, methods, and formulations
RU2538727C1 (ru) * 2013-11-15 2015-01-10 Закрытое акционерное общество "Институт экспериментальной фармакологии" Анальгетическое средство пептидной структуры на основе тридекапептида, содержащего d-октааргининовый вектор
CN104844471B (zh) * 2015-04-21 2017-05-03 苏州远智医药科技有限公司 一种作为dor受体拮抗剂的化合物
CN109896991B (zh) * 2017-12-08 2020-11-20 苏州远智医药科技有限公司 一种δ阿片受体拮抗剂及其用途和药物组合物
JP7413048B2 (ja) 2020-01-30 2024-01-15 三和シヤッター工業株式会社 シャッターカーテン及びシャッターカーテンの梱包方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623394A (es) *
DE1203247B (de) * 1961-10-10 1965-10-21 Koninklijke Pharma Fab Nv Verfahren zur Herstellung von Diphenylalkenyl-aminen sowie deren nicht-toxischen Salzen
GB956616A (en) * 1961-10-10 1964-04-29 Koninklijke Pharma Fab Nv New substituted diphenylalkylamines
DE1149002B (de) * 1961-10-19 1963-05-22 Giulini Gmbh Geb Verfahren zur Herstellung von blutdrucksteigernden Salzen von N, N-Dialkyl-2-aethyl-3, 3-diphenyl-propen-(2)-yl-aminen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8164251B2 (en) 2005-11-18 2012-04-24 Idemitsu Kosan Co., Ltd. Aromatic amine derivatives and organic electroluminescence devices using the same

Also Published As

Publication number Publication date
CN1197059A (zh) 1998-10-28
CO4940510A1 (es) 2000-07-24
IL123647A (en) 2004-01-04
UY24919A1 (es) 2001-08-27
PL325322A1 (en) 1998-09-28
IL123647A0 (en) 1998-10-30
MY118828A (en) 2005-01-31
HU9800555D0 (en) 1998-05-28
KR100579428B1 (ko) 2006-10-11
RU2197474C2 (ru) 2003-01-27
AU5840898A (en) 1999-02-11
EP0864559B1 (de) 2002-06-05
ATE218534T1 (de) 2002-06-15
PL191727B1 (pl) 2006-06-30
SK284279B6 (sk) 2004-12-01
DK0864559T3 (da) 2002-08-05
CN1243721C (zh) 2006-03-01
KR19980080219A (ko) 1998-11-25
HUP9800555A2 (hu) 1999-06-28
NO981121D0 (no) 1998-03-13
AU728501B2 (en) 2001-01-11
EP0864559A1 (de) 1998-09-16
NO981121L (no) 1998-09-15
SK33398A3 (en) 1998-11-04
NZ329951A (en) 1998-08-26
US6022895A (en) 2000-02-08
HU226060B1 (en) 2008-04-28
JP4132189B2 (ja) 2008-08-13
ES2178055T3 (es) 2002-12-16
HUP9800555A3 (en) 2000-04-28
ZA982157B (en) 1998-09-15
SI0864559T1 (en) 2002-08-31
UA56997C2 (uk) 2003-06-16
CZ295522B6 (cs) 2005-08-17
CA2231975A1 (en) 1998-09-14
DE19805370A1 (de) 1998-09-17
PE59899A1 (es) 1999-07-10
JPH10338665A (ja) 1998-12-22
NO311128B1 (no) 2001-10-15
DE59804276D1 (de) 2002-07-11
CZ75598A3 (cs) 1998-09-16
AR010129A1 (es) 2000-05-17
CA2231975C (en) 2007-09-11
PT864559E (pt) 2002-11-29

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100219