HK1015137A1 - Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid - Google Patents

Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid

Info

Publication number
HK1015137A1
HK1015137A1 HK98115478A HK98115478A HK1015137A1 HK 1015137 A1 HK1015137 A1 HK 1015137A1 HK 98115478 A HK98115478 A HK 98115478A HK 98115478 A HK98115478 A HK 98115478A HK 1015137 A1 HK1015137 A1 HK 1015137A1
Authority
HK
Hong Kong
Prior art keywords
antiviral
deoxy
alpha
substituted
neuraminic acid
Prior art date
Application number
HK98115478A
Other languages
English (en)
Inventor
Itzstein Von
Wen-Yang Wu
Tho Van Phan
Betty Jin
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of HK1015137A1 publication Critical patent/HK1015137A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK98115478A 1991-10-23 1998-12-24 Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid HK1015137A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPK905191 1991-10-23

Publications (1)

Publication Number Publication Date
HK1015137A1 true HK1015137A1 (en) 1999-10-08

Family

ID=3775765

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98115478A HK1015137A1 (en) 1991-10-23 1998-12-24 Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid

Country Status (11)

Country Link
EP (1) EP0539204B1 (fr)
JP (1) JP2925863B2 (fr)
AT (1) ATE161836T1 (fr)
AU (1) AU659501B2 (fr)
CA (1) CA2081068C (fr)
DE (1) DE69223914T2 (fr)
DK (1) DK0539204T3 (fr)
ES (1) ES2113413T3 (fr)
GR (1) GR3026218T3 (fr)
HK (1) HK1015137A1 (fr)
ZA (1) ZA928170B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9220241D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9220327D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
AUPM354694A0 (en) * 1994-01-27 1994-02-17 Biota Scientific Management Pty Ltd Chemical compounds
GB9410817D0 (en) * 1994-05-28 1994-07-20 Glaxo Group Ltd Medicaments
US5561146A (en) * 1994-06-10 1996-10-01 Bristol-Myers Squibb Company Modified guanidino and amidino thrombin inhibitors
US5512596A (en) * 1994-09-02 1996-04-30 Gilead Sciences, Inc. Aromatic compounds
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
WO1996026933A1 (fr) 1995-02-27 1996-09-06 Gilead Sciences, Inc. Nouveaux inhibiteurs selectifs de neuraminidases virales ou bacteriennes
CA2546660C (fr) * 1995-02-27 2009-08-11 Gilead Sciences Inc. Inhibiteurs selectifs de neuraminidase virale ou bacterienne
US5602277A (en) * 1995-03-30 1997-02-11 Biocryst Pharmaceuticals, Inc. Substituted benzene derivatives useful as neuraminidase inhibitors
WO1996036628A1 (fr) * 1995-05-19 1996-11-21 Biota Scientific Management Pty. Ltd. Derives du 6-carboxamidodihydropyrane
GB9516276D0 (en) * 1995-08-08 1995-10-11 Biota Scient Management Chemical compounds
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
PT823428E (pt) * 1996-07-22 2002-04-29 Sankyo Co Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
PT934939E (pt) * 1996-08-13 2003-07-31 Sankyo Co Compostos de acido neuraminico
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
WO1998011083A1 (fr) * 1996-09-10 1998-03-19 Daikin Industries, Ltd. Acides sialiques 2,7-dideoxy-7-fluoro- 2, 3-didehydro a quadruple substitution
CN1238762A (zh) * 1996-10-21 1999-12-15 吉里德科学公司 哌啶化合物
US5994377A (en) 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
CA2271249C (fr) * 1996-11-14 2010-07-20 Biota Scientific Management Pty. Ltd. Composes macromoleculaires ayant la capacite de se lier a des neuraminidases
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
US6455571B1 (en) 1998-04-23 2002-09-24 Abbott Laboratories Inhibitors of neuraminidases
US6518305B1 (en) 1998-04-23 2003-02-11 Abbott Laboratories Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6593314B1 (en) 1999-10-19 2003-07-15 Abbott Laboratories Neuraminidase inhibitors
WO2002092555A1 (fr) * 2001-05-11 2002-11-21 Sankyo Company, Limited Derives d'acides sialiques
RU2299075C2 (ru) 2003-02-10 2007-05-20 Ниппон Сокубаи Ко., Лтд. Гигроскопическая добавка
AU2008208865B2 (en) 2007-01-23 2013-01-24 Therapicon Srl Antiviral compounds
WO2009004899A1 (fr) * 2007-06-15 2009-01-08 National University Corporation Hokkaido University Inhibiteur de sialidase
JP2012510456A (ja) 2008-11-28 2012-05-10 シプラ・リミテッド ザナミビルの製造方法及び該方法に使用するための中間体
EA201101564A1 (ru) 2009-05-15 2012-07-30 Редкс Фарма Лимитед Редокс производные лекарственных средств
IT1396620B1 (it) 2009-11-25 2012-12-14 Therapicon Srl Analoghi chimerici
WO2012114350A1 (fr) 2011-02-24 2012-08-30 Cadila Healthcare Limited Procédé de préparation de zanamivir
DE102011117128A1 (de) * 2011-10-28 2013-05-02 Christian-Albrechts-Universität Zu Kiel Verbindungen zur Therapie der Influenza

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) * 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
GB9220241D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
ZA928170B (en) 1993-11-15
DE69223914D1 (de) 1998-02-12
CA2081068A1 (fr) 1993-04-24
AU2724292A (en) 1993-04-29
JP2925863B2 (ja) 1999-07-28
CA2081068C (fr) 2005-11-29
DE69223914T2 (de) 1998-04-30
EP0539204A1 (fr) 1993-04-28
ES2113413T3 (es) 1998-05-01
AU659501B2 (en) 1995-05-18
GR3026218T3 (en) 1998-05-29
ATE161836T1 (de) 1998-01-15
JPH0625209A (ja) 1994-02-01
EP0539204B1 (fr) 1998-01-07
DK0539204T3 (da) 1998-09-07

Similar Documents

Publication Publication Date Title
HK1015137A1 (en) Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid
PT83647A (en) Process for the preparation of novel pharmaceutical benzimidazole derivatives and of pharmaceutical compositions containing the same
NZ244021A (en) Benzylthiazolidinedione derivatives, preparation and pharmaceutical compositions thereof
IL101883A0 (en) Antiviral combinations and pharmaceutical compositions containing them
HUT61004A (en) Process for producing quinoxaline derivatives and pharmaceutical compositions comprising such compounds as active ingredient
GR3006091T3 (fr)
GR3024686T3 (en) Novel guinolone and naphthyridone derivatives.
EP0321968A3 (en) Compounds active on the cardiovascular system
SE8600658D0 (sv) Novel composition of matter
ES2039267T3 (es) Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos.
EP0331092A3 (en) Alpha-amino-carboxylic-acid derivatives, their preparation and use
DE68927055D1 (de) 2',5'-oligoadenylat-derivate zur verwendung als heilmittel
DE69300296D1 (de) Thiochromanderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
FI902901A0 (fi) Dibenzol/1,5/dioxocin-5-one-derivat, deras anvaendning i laekemedel och foerfarande foer deras framstaellning.
DK0418990T3 (da) 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
ITMI911845A1 (it) Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico.
EP0321967A3 (en) Compounds active on the cardiovascular system
IL85508A (en) 2-substituted-4-(2-benzyl-aminophenyl)-1,4,5,7-tetra-hydro-5-oxofuro(3,4,-b)-pyridine-3-carboxylic acid derivatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)