ZA928170B - Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid - Google Patents

Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid

Info

Publication number
ZA928170B
ZA928170B ZA928170A ZA928170A ZA928170B ZA 928170 B ZA928170 B ZA 928170B ZA 928170 A ZA928170 A ZA 928170A ZA 928170 A ZA928170 A ZA 928170A ZA 928170 B ZA928170 B ZA 928170B
Authority
ZA
South Africa
Prior art keywords
derivatives
antiviral
didehydro
deoxy
alpha
Prior art date
Application number
ZA928170A
Other languages
English (en)
Inventor
Laurence Mark Von Itzstein
Wen-Yang Wu
Tho Van Phan
Basil Danylec
Betty Jin
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of ZA928170B publication Critical patent/ZA928170B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA928170A 1991-10-23 1992-10-22 Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid ZA928170B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPK905191 1991-10-23

Publications (1)

Publication Number Publication Date
ZA928170B true ZA928170B (en) 1993-11-15

Family

ID=3775765

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928170A ZA928170B (en) 1991-10-23 1992-10-22 Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid

Country Status (11)

Country Link
EP (1) EP0539204B1 (xx)
JP (1) JP2925863B2 (xx)
AT (1) ATE161836T1 (xx)
AU (1) AU659501B2 (xx)
CA (1) CA2081068C (xx)
DE (1) DE69223914T2 (xx)
DK (1) DK0539204T3 (xx)
ES (1) ES2113413T3 (xx)
GR (1) GR3026218T3 (xx)
HK (1) HK1015137A1 (xx)
ZA (1) ZA928170B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9220327D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9220241D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
AUPM354694A0 (en) * 1994-01-27 1994-02-17 Biota Scientific Management Pty Ltd Chemical compounds
GB9410817D0 (en) * 1994-05-28 1994-07-20 Glaxo Group Ltd Medicaments
US5561146A (en) * 1994-06-10 1996-10-01 Bristol-Myers Squibb Company Modified guanidino and amidino thrombin inhibitors
US5512596A (en) * 1994-09-02 1996-04-30 Gilead Sciences, Inc. Aromatic compounds
DE759917T1 (de) * 1995-02-27 1998-10-22 Gilead Sciences Inc Neue selektive inhibitoren viraler oder bakterieller neuraminidasen
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
CN102952033A (zh) * 1995-02-27 2013-03-06 吉里德科学公司 新颖化合物,其合成方法及治疗用途
US5602277A (en) * 1995-03-30 1997-02-11 Biocryst Pharmaceuticals, Inc. Substituted benzene derivatives useful as neuraminidase inhibitors
EP0833825B1 (en) * 1995-05-19 2001-09-26 Biota Scientific Management Pty. Ltd. 6-carboxamido dihydropyran derivatives
GB9516276D0 (en) * 1995-08-08 1995-10-11 Biota Scient Management Chemical compounds
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
ES2167682T3 (es) * 1996-07-22 2002-05-16 Sankyo Co Derivados del acido neuraminico, su preparacion y su uso medico.
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
DE69721553T2 (de) * 1996-08-13 2004-07-22 Sankyo Co., Ltd. Verbindungen der neuraminsaeure
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
AU711845B2 (en) * 1996-09-10 1999-10-21 Daikin Industries, Ltd. 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds
US5994377A (en) * 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
JP2001502690A (ja) * 1996-10-21 2001-02-27 ギリアード サイエンシーズ，インコーポレイテッド ピペリジン化合物
TR199901081T2 (xx) * 1996-11-14 1999-08-23 Biota Scientific Management Pty.Ltd. Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler.
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
US6455571B1 (en) 1998-04-23 2002-09-24 Abbott Laboratories Inhibitors of neuraminidases
US6518305B1 (en) 1998-04-23 2003-02-11 Abbott Laboratories Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6593314B1 (en) 1999-10-19 2003-07-15 Abbott Laboratories Neuraminidase inhibitors
WO2002092555A1 (fr) * 2001-05-11 2002-11-21 Sankyo Company, Limited Derives d'acides sialiques
US7638570B2 (en) 2003-02-10 2009-12-29 Nippon Shokubai Co., Ltd. Water-absorbing agent
JP5345073B2 (ja) 2007-01-23 2013-11-20 テラピコン エス．アール．エル． 抗ウイルス化合物
WO2009004899A1 (ja) * 2007-06-15 2009-01-08 National University Corporation Hokkaido University シアリダーゼ阻害剤
CA2744793A1 (en) 2008-11-28 2010-06-03 Cipla Limited Process for preparing zanamivir and intermediates for use in the process
AU2010247141A1 (en) 2009-05-15 2011-12-15 Redx Pharma Plc Redox drug derivatives
IT1396620B1 (it) 2009-11-25 2012-12-14 Therapicon Srl Analoghi chimerici
EP2678324A1 (en) 2011-02-24 2014-01-01 Cadila Healthcare Limited Process for the preparation of zanamivir
DE102011117128A1 (de) * 2011-10-28 2013-05-02 Christian-Albrechts-Universität Zu Kiel Verbindungen zur Therapie der Influenza

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ288492B6 (en) * 1990-04-24 2001-06-13 Biota Scient Management Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon
GB9220241D0 (en) * 1992-09-25 1992-11-11 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
CA2081068A1 (en) 1993-04-24
GR3026218T3 (en) 1998-05-29
CA2081068C (en) 2005-11-29
AU2724292A (en) 1993-04-29
JP2925863B2 (ja) 1999-07-28
ES2113413T3 (es) 1998-05-01
HK1015137A1 (en) 1999-10-08
DK0539204T3 (da) 1998-09-07
ATE161836T1 (de) 1998-01-15
DE69223914T2 (de) 1998-04-30
EP0539204A1 (en) 1993-04-28
JPH0625209A (ja) 1994-02-01
AU659501B2 (en) 1995-05-18
DE69223914D1 (de) 1998-02-12
EP0539204B1 (en) 1998-01-07

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