GR3026218T3 - Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid - Google Patents
Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acidInfo
- Publication number
- GR3026218T3 GR3026218T3 GR980400397T GR980400397T GR3026218T3 GR 3026218 T3 GR3026218 T3 GR 3026218T3 GR 980400397 T GR980400397 T GR 980400397T GR 980400397 T GR980400397 T GR 980400397T GR 3026218 T3 GR3026218 T3 GR 3026218T3
- Authority
- GR
- Greece
- Prior art keywords
- antiviral
- deoxy
- alpha
- substituted
- neuraminic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPK905191 | 1991-10-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3026218T3 true GR3026218T3 (en) | 1998-05-29 |
Family
ID=3775765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980400397T GR3026218T3 (en) | 1991-10-23 | 1998-02-25 | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0539204B1 (el) |
JP (1) | JP2925863B2 (el) |
AT (1) | ATE161836T1 (el) |
AU (1) | AU659501B2 (el) |
CA (1) | CA2081068C (el) |
DE (1) | DE69223914T2 (el) |
DK (1) | DK0539204T3 (el) |
ES (1) | ES2113413T3 (el) |
GR (1) | GR3026218T3 (el) |
HK (1) | HK1015137A1 (el) |
ZA (1) | ZA928170B (el) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9220327D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
US5561146A (en) * | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
HU228450B1 (en) * | 1995-02-27 | 2013-03-28 | Gilead Sciences Inc | Novel selective inhibitors of viral or bacterial neuraminidases |
HU229200B1 (en) * | 1995-02-27 | 2013-09-30 | Gilead Sciences Inc | Selective inhibitors of viral or bacterial neuraminidase |
US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
US5602277A (en) * | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
EP0833825B1 (en) * | 1995-05-19 | 2001-09-26 | Biota Scientific Management Pty. Ltd. | 6-carboxamido dihydropyran derivatives |
GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
ATE211468T1 (de) * | 1996-07-22 | 2002-01-15 | Sankyo Co | Neuraminsäuredervate, ihre herstellung und medizinische verwendung |
US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
NZ334101A (en) * | 1996-08-13 | 2001-07-27 | Sankyo Co | Neuraminic acid derivatives and use in treating viral infections |
US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
WO1998011083A1 (fr) * | 1996-09-10 | 1998-03-19 | Daikin Industries, Ltd. | Acides sialiques 2,7-dideoxy-7-fluoro- 2, 3-didehydro a quadruple substitution |
WO1998017647A1 (en) * | 1996-10-21 | 1998-04-30 | Gilead Sciences, Inc. | Piperidine compounds |
US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
US6680054B1 (en) * | 1996-11-14 | 2004-01-20 | Biota Scientific Management Pty Ltd. | Macromolecular neuraminidase-binding compounds |
US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
WO2002092555A1 (fr) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Derives d'acides sialiques |
CN100346843C (zh) | 2003-02-10 | 2007-11-07 | 株式会社日本触媒 | 吸水剂 |
EP2125848B1 (en) | 2007-01-23 | 2014-09-10 | Therapicon Srl | Antiviral compounds |
WO2009004899A1 (ja) * | 2007-06-15 | 2009-01-08 | National University Corporation Hokkaido University | シアリダーゼ阻害剤 |
EP2358695B1 (en) | 2008-11-28 | 2014-07-02 | Cipla Limited | Process for preparing zanamivir and intermediates for use in the process |
AU2010247141A1 (en) | 2009-05-15 | 2011-12-15 | Redx Pharma Plc | Redox drug derivatives |
IT1396620B1 (it) | 2009-11-25 | 2012-12-14 | Therapicon Srl | Analoghi chimerici |
EP2678324A1 (en) | 2011-02-24 | 2014-01-01 | Cadila Healthcare Limited | Process for the preparation of zanamivir |
DE102011117128A1 (de) * | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ288492B6 (en) * | 1990-04-24 | 2001-06-13 | Biota Scient Management | Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon |
GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
-
1992
- 1992-10-21 AU AU27242/92A patent/AU659501B2/en not_active Ceased
- 1992-10-21 CA CA002081068A patent/CA2081068C/en not_active Expired - Fee Related
- 1992-10-22 DK DK92309684T patent/DK0539204T3/da active
- 1992-10-22 DE DE69223914T patent/DE69223914T2/de not_active Expired - Lifetime
- 1992-10-22 EP EP92309684A patent/EP0539204B1/en not_active Expired - Lifetime
- 1992-10-22 ES ES92309684T patent/ES2113413T3/es not_active Expired - Lifetime
- 1992-10-22 ZA ZA928170A patent/ZA928170B/xx unknown
- 1992-10-22 AT AT92309684T patent/ATE161836T1/de not_active IP Right Cessation
- 1992-10-23 JP JP4309626A patent/JP2925863B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-25 GR GR980400397T patent/GR3026218T3/el unknown
- 1998-12-24 HK HK98115478A patent/HK1015137A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE161836T1 (de) | 1998-01-15 |
AU659501B2 (en) | 1995-05-18 |
JPH0625209A (ja) | 1994-02-01 |
DK0539204T3 (da) | 1998-09-07 |
CA2081068A1 (en) | 1993-04-24 |
DE69223914D1 (de) | 1998-02-12 |
ES2113413T3 (es) | 1998-05-01 |
AU2724292A (en) | 1993-04-29 |
CA2081068C (en) | 2005-11-29 |
HK1015137A1 (en) | 1999-10-08 |
ZA928170B (en) | 1993-11-15 |
JP2925863B2 (ja) | 1999-07-28 |
DE69223914T2 (de) | 1998-04-30 |
EP0539204A1 (en) | 1993-04-28 |
EP0539204B1 (en) | 1998-01-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GR3026218T3 (en) | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid | |
PT83647A (en) | Process for the preparation of novel pharmaceutical benzimidazole derivatives and of pharmaceutical compositions containing the same | |
NZ244021A (en) | Benzylthiazolidinedione derivatives, preparation and pharmaceutical compositions thereof | |
IL101883A0 (en) | Antiviral combinations and pharmaceutical compositions containing them | |
IL94819A0 (en) | 11beta-aryl-4-estrene derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
HUT61004A (en) | Process for producing quinoxaline derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
GR3006091T3 (el) | ||
GR3024686T3 (en) | Novel guinolone and naphthyridone derivatives. | |
EP0321968A3 (en) | Compounds active on the cardiovascular system | |
SE8600658D0 (sv) | Novel composition of matter | |
ES2039267T3 (es) | Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos. | |
DE68927055D1 (de) | 2',5'-oligoadenylat-derivate zur verwendung als heilmittel | |
DE69300296T2 (de) | Thiochromanderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. | |
FI902901A0 (fi) | Dibenzol/1,5/dioxocin-5-one-derivat, deras anvaendning i laekemedel och foerfarande foer deras framstaellning. | |
DK0418990T3 (da) | 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler | |
ITMI911845A1 (it) | Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico. | |
EP0321967A3 (en) | Compounds active on the cardiovascular system | |
IL85508A (en) | 2-substituted-4-(2-benzyl-aminophenyl)-1,4,5,7-tetra-hydro-5-oxofuro(3,4,-b)-pyridine-3-carboxylic acid derivatives and pharmaceutical compositions containing them |