DK0539204T3 - Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre - Google Patents
Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyreInfo
- Publication number
- DK0539204T3 DK0539204T3 DK92309684T DK92309684T DK0539204T3 DK 0539204 T3 DK0539204 T3 DK 0539204T3 DK 92309684 T DK92309684 T DK 92309684T DK 92309684 T DK92309684 T DK 92309684T DK 0539204 T3 DK0539204 T3 DK 0539204T3
- Authority
- DK
- Denmark
- Prior art keywords
- antiviral
- deoxy
- alpha
- substituted
- neuraminic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPK905191 | 1991-10-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0539204T3 true DK0539204T3 (da) | 1998-09-07 |
Family
ID=3775765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92309684T DK0539204T3 (da) | 1991-10-23 | 1992-10-22 | Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0539204B1 (el) |
JP (1) | JP2925863B2 (el) |
AT (1) | ATE161836T1 (el) |
AU (1) | AU659501B2 (el) |
CA (1) | CA2081068C (el) |
DE (1) | DE69223914T2 (el) |
DK (1) | DK0539204T3 (el) |
ES (1) | ES2113413T3 (el) |
GR (1) | GR3026218T3 (el) |
HK (1) | HK1015137A1 (el) |
ZA (1) | ZA928170B (el) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9220327D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
US5561146A (en) * | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
DE759917T1 (de) * | 1995-02-27 | 1998-10-22 | Gilead Sciences Inc | Neue selektive inhibitoren viraler oder bakterieller neuraminidasen |
US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
CN102952033A (zh) * | 1995-02-27 | 2013-03-06 | 吉里德科学公司 | 新颖化合物,其合成方法及治疗用途 |
US5602277A (en) * | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
EP0833825B1 (en) * | 1995-05-19 | 2001-09-26 | Biota Scientific Management Pty. Ltd. | 6-carboxamido dihydropyran derivatives |
GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
ES2167682T3 (es) * | 1996-07-22 | 2002-05-16 | Sankyo Co | Derivados del acido neuraminico, su preparacion y su uso medico. |
US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
DE69721553T2 (de) * | 1996-08-13 | 2004-07-22 | Sankyo Co., Ltd. | Verbindungen der neuraminsaeure |
US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
AU711845B2 (en) * | 1996-09-10 | 1999-10-21 | Daikin Industries, Ltd. | 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds |
US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
JP2001502690A (ja) * | 1996-10-21 | 2001-02-27 | ギリアード サイエンシーズ,インコーポレイテッド | ピペリジン化合物 |
TR199901081T2 (xx) * | 1996-11-14 | 1999-08-23 | Biota Scientific Management Pty.Ltd. | Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler. |
US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
WO2002092555A1 (fr) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Derives d'acides sialiques |
US7638570B2 (en) | 2003-02-10 | 2009-12-29 | Nippon Shokubai Co., Ltd. | Water-absorbing agent |
JP5345073B2 (ja) | 2007-01-23 | 2013-11-20 | テラピコン エス.アール.エル. | 抗ウイルス化合物 |
WO2009004899A1 (ja) * | 2007-06-15 | 2009-01-08 | National University Corporation Hokkaido University | シアリダーゼ阻害剤 |
CA2744793A1 (en) | 2008-11-28 | 2010-06-03 | Cipla Limited | Process for preparing zanamivir and intermediates for use in the process |
AU2010247141A1 (en) | 2009-05-15 | 2011-12-15 | Redx Pharma Plc | Redox drug derivatives |
IT1396620B1 (it) | 2009-11-25 | 2012-12-14 | Therapicon Srl | Analoghi chimerici |
EP2678324A1 (en) | 2011-02-24 | 2014-01-01 | Cadila Healthcare Limited | Process for the preparation of zanamivir |
DE102011117128A1 (de) * | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ288492B6 (en) * | 1990-04-24 | 2001-06-13 | Biota Scient Management | Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon |
GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
-
1992
- 1992-10-21 CA CA002081068A patent/CA2081068C/en not_active Expired - Fee Related
- 1992-10-21 AU AU27242/92A patent/AU659501B2/en not_active Ceased
- 1992-10-22 AT AT92309684T patent/ATE161836T1/de not_active IP Right Cessation
- 1992-10-22 ES ES92309684T patent/ES2113413T3/es not_active Expired - Lifetime
- 1992-10-22 ZA ZA928170A patent/ZA928170B/xx unknown
- 1992-10-22 EP EP92309684A patent/EP0539204B1/en not_active Expired - Lifetime
- 1992-10-22 DK DK92309684T patent/DK0539204T3/da active
- 1992-10-22 DE DE69223914T patent/DE69223914T2/de not_active Expired - Lifetime
- 1992-10-23 JP JP4309626A patent/JP2925863B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-25 GR GR980400397T patent/GR3026218T3/el unknown
- 1998-12-24 HK HK98115478A patent/HK1015137A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2081068A1 (en) | 1993-04-24 |
GR3026218T3 (en) | 1998-05-29 |
CA2081068C (en) | 2005-11-29 |
AU2724292A (en) | 1993-04-29 |
JP2925863B2 (ja) | 1999-07-28 |
ES2113413T3 (es) | 1998-05-01 |
HK1015137A1 (en) | 1999-10-08 |
ATE161836T1 (de) | 1998-01-15 |
DE69223914T2 (de) | 1998-04-30 |
EP0539204A1 (en) | 1993-04-28 |
JPH0625209A (ja) | 1994-02-01 |
AU659501B2 (en) | 1995-05-18 |
ZA928170B (en) | 1993-11-15 |
DE69223914D1 (de) | 1998-02-12 |
EP0539204B1 (en) | 1998-01-07 |
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