HK1013420A1 - Molecule labelling using 2-hydraninopyridine derivatives - Google Patents

Molecule labelling using 2-hydraninopyridine derivatives

Info

Publication number
HK1013420A1
HK1013420A1 HK98114895A HK98114895A HK1013420A1 HK 1013420 A1 HK1013420 A1 HK 1013420A1 HK 98114895 A HK98114895 A HK 98114895A HK 98114895 A HK98114895 A HK 98114895A HK 1013420 A1 HK1013420 A1 HK 1013420A1
Authority
HK
Hong Kong
Prior art keywords
pct
compound
hydraninopyridine
derivatives
date
Prior art date
Application number
HK98114895A
Other languages
English (en)
Inventor
Michael Jeffrey Abrams
Gary James Bridger
David Aaron Schwartz
Sreenivasan Padmanabhan
Michael Evert Ultee
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of HK1013420A1 publication Critical patent/HK1013420A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
HK98114895A 1992-11-05 1998-12-22 Molecule labelling using 2-hydraninopyridine derivatives HK1013420A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929223168A GB9223168D0 (en) 1992-11-05 1992-11-05 Improvements in molecule labelling
PCT/GB1993/002259 WO1994010149A1 (fr) 1992-11-05 1993-11-03 Marquage de molecules a l'aide de derives de 2-hydraminopyridine

Publications (1)

Publication Number Publication Date
HK1013420A1 true HK1013420A1 (en) 1999-08-27

Family

ID=10724568

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98114895A HK1013420A1 (en) 1992-11-05 1998-12-22 Molecule labelling using 2-hydraninopyridine derivatives

Country Status (19)

Country Link
US (1) US5679778A (fr)
EP (1) EP0667859B1 (fr)
JP (1) JP3542597B2 (fr)
KR (1) KR100295545B1 (fr)
AT (1) ATE195730T1 (fr)
AU (1) AU676863B2 (fr)
CA (1) CA2148595C (fr)
DE (1) DE69329293T2 (fr)
DK (1) DK0667859T3 (fr)
ES (1) ES2150950T3 (fr)
FI (1) FI113044B (fr)
GB (1) GB9223168D0 (fr)
GR (1) GR3034883T3 (fr)
HK (1) HK1013420A1 (fr)
HU (1) HU226459B1 (fr)
NO (1) NO305364B1 (fr)
NZ (1) NZ257376A (fr)
PT (1) PT667859E (fr)
WO (1) WO1994010149A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942210A (en) * 1994-11-15 1999-08-24 Cytogen Corporation Methods for lyoprotecting a macromolecule using tricine
US5919934A (en) * 1997-02-19 1999-07-06 The George Washington University Compounds, compositions, and methods for cancer imaging and therapy
HUP0001261A3 (en) 1997-04-30 2001-11-28 Univ Washington Seattle Method of imaging cell death in vivo
US6403054B1 (en) * 1997-05-28 2002-06-11 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US6844333B1 (en) * 1999-03-26 2005-01-18 The Trustees Of The University Of Pennsylvania Method of treating atherosclerosis
CA2723664A1 (fr) * 2000-03-22 2001-09-27 Solulink, Incorporated Agents de reticulation bifonctionnels a base d'hydrazine et de carbonyle
US6686461B1 (en) 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
US7102024B1 (en) 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
WO2002080754A2 (fr) 2001-04-03 2002-10-17 Theseus Imaging Corporation Methodes d'utilisation d'une annexine permettant de visualiser la mort cellulaire in vivo et de traiter des etats pathologiques
WO2002082044A2 (fr) 2001-04-03 2002-10-17 The Board Of Trustees Of The Leland Stanford Junior University Imagerie in-vivo de l'apoptose
GB0130845D0 (en) * 2001-12-22 2002-02-06 James Peter Analysis
US7158353B2 (en) * 2003-11-06 2007-01-02 Seagate Technology Llc Magnetoresistive sensor having specular sidewall layers
JP5107716B2 (ja) * 2004-11-05 2012-12-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 分子治療用生分解性リンカー
EP2942351B1 (fr) * 2011-01-31 2016-10-12 ETH Zurich Réactifs de réticulation trifonctionnelle
CN103582496B (zh) 2011-06-03 2016-05-11 3M创新有限公司 具有聚乙二醇链段的异双官能连接基以及由其制成的免疫应答调节剂缀合物
BR112013031039B1 (pt) 2011-06-03 2020-04-28 3M Innovative Properties Co compostos de hidrazino 1h-imidazoquinolina-4-aminas, conjugados feitos destes compostos, composição e composição farmacêutica compreendendo ditos compostos e conjugados, usos dos mesmos e método de fabricação do conjugado

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
IL93432A (en) * 1989-02-24 1994-02-27 Johnson Mathey Inc Hydrazines and hydrazides, their conjugates with macromolecules, and such conjugates labeled with metallic ions
US5112953A (en) * 1989-12-29 1992-05-12 Neorx Corporation Radiolabeled proteins for diagnostic or therapeutic use

Also Published As

Publication number Publication date
DK0667859T3 (da) 2000-10-16
AU676863B2 (en) 1997-03-27
ATE195730T1 (de) 2000-09-15
NO951751D0 (no) 1995-05-04
ES2150950T3 (es) 2000-12-16
CA2148595A1 (fr) 1994-05-11
EP0667859A1 (fr) 1995-08-23
GR3034883T3 (en) 2001-02-28
FI952141A (fi) 1995-05-04
AU5375594A (en) 1994-05-24
JP3542597B2 (ja) 2004-07-14
WO1994010149A1 (fr) 1994-05-11
PT667859E (pt) 2001-02-28
US5679778A (en) 1997-10-21
DE69329293T2 (de) 2000-12-28
KR100295545B1 (ko) 2001-09-17
DE69329293D1 (de) 2000-09-28
CA2148595C (fr) 2002-05-21
GB9223168D0 (en) 1992-12-16
HUT72332A (en) 1996-04-29
NO951751L (no) 1995-06-12
EP0667859B1 (fr) 2000-08-23
JPH08502744A (ja) 1996-03-26
NZ257376A (en) 1996-02-27
NO305364B1 (no) 1999-05-18
FI952141A0 (fi) 1995-05-04
FI113044B (fi) 2004-02-27
KR950704256A (ko) 1995-11-17
HU226459B1 (en) 2008-12-29

Similar Documents

Publication Publication Date Title
HK1013420A1 (en) Molecule labelling using 2-hydraninopyridine derivatives
FI914163A0 (fi) Heterocykliska derivat.
EP1006122A4 (fr) Derives de phenylethylamine
FI903917A0 (fi) Foerfarande foer framstaellning av med metallradionuklider maerkta proteiner.
AU1070895A (en) Indole-derived arylpiperazines as ligands for 5HT1-like receptors 5HT1B and 5HT1D
CA2211385A1 (fr) Derives n-1-carboxyalkyle de lsd
DE50004382D1 (de) Verfahren zur Herstellung von Guanidinderivaten
EP0147181A3 (fr) Dérivés de l'acide thiazolylacétique et leur préparation
KR850007067A (ko) 옥스아자포스포린 유도체의 염의 제조방법
IN185708B (fr)
KR960704889A (ko) 인돌리진 유도체의 제조방법 (Process for the preparation of indolizine derivatives)
FR2645535B1 (fr) Preparation d'ethenes substitues
IL99777A0 (en) Indole derivatives,processes for their preparation and pharmaceutical compositions containing them
KR920004377A (ko) 피리딘카복실산 아미드 유도체 및 이를 함유하는 약제학적 조성물
KR940014350A (ko) 신규 1, 6-디아미노 피리미딘-4-티온 유도체 및 이의 제조방법
TW352391B (en) Novel cyanine dyes, the intermediates and preparation thereof
TH16053A (fr)
KR950008520A (ko) 세팔로스포린 유도체 및 그의 제조방법

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20131102