FI952141A0 - Molekyylimerkintä käyttäen 2-hydraninopyridiinijohdannaisia - Google Patents

Molekyylimerkintä käyttäen 2-hydraninopyridiinijohdannaisia

Info

Publication number
FI952141A0
FI952141A0 FI952141A FI952141A FI952141A0 FI 952141 A0 FI952141 A0 FI 952141A0 FI 952141 A FI952141 A FI 952141A FI 952141 A FI952141 A FI 952141A FI 952141 A0 FI952141 A0 FI 952141A0
Authority
FI
Finland
Prior art keywords
pct
compound
hydraninopyridine
derivatives
date
Prior art date
Application number
FI952141A
Other languages
English (en)
Swedish (sv)
Other versions
FI113044B (fi
FI952141A (fi
Inventor
Michael Jeffrey Abrams
Gary James Bridger
David Aaron Schwartz
Sreenivasan Padmanabhan
Michael Evert Ultee
Original Assignee
Johnson Matthey Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey Plc filed Critical Johnson Matthey Plc
Publication of FI952141A publication Critical patent/FI952141A/fi
Publication of FI952141A0 publication Critical patent/FI952141A0/fi
Application granted granted Critical
Publication of FI113044B publication Critical patent/FI113044B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Adhesives Or Adhesive Processes (AREA)
FI952141A 1992-11-05 1995-05-04 2-hydratsinopyridiinijohdannaisia FI113044B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9223168 1992-11-05
GB929223168A GB9223168D0 (en) 1992-11-05 1992-11-05 Improvements in molecule labelling
GB9302259 1993-02-05
PCT/GB1993/002259 WO1994010149A1 (en) 1992-11-05 1993-11-03 Molecule labelling using 2-hydraninopyridine derivatives

Publications (3)

Publication Number Publication Date
FI952141A FI952141A (fi) 1995-05-04
FI952141A0 true FI952141A0 (fi) 1995-05-04
FI113044B FI113044B (fi) 2004-02-27

Family

ID=10724568

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952141A FI113044B (fi) 1992-11-05 1995-05-04 2-hydratsinopyridiinijohdannaisia

Country Status (19)

Country Link
US (1) US5679778A (fi)
EP (1) EP0667859B1 (fi)
JP (1) JP3542597B2 (fi)
KR (1) KR100295545B1 (fi)
AT (1) ATE195730T1 (fi)
AU (1) AU676863B2 (fi)
CA (1) CA2148595C (fi)
DE (1) DE69329293T2 (fi)
DK (1) DK0667859T3 (fi)
ES (1) ES2150950T3 (fi)
FI (1) FI113044B (fi)
GB (1) GB9223168D0 (fi)
GR (1) GR3034883T3 (fi)
HK (1) HK1013420A1 (fi)
HU (1) HU226459B1 (fi)
NO (1) NO305364B1 (fi)
NZ (1) NZ257376A (fi)
PT (1) PT667859E (fi)
WO (1) WO1994010149A1 (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942210A (en) * 1994-11-15 1999-08-24 Cytogen Corporation Methods for lyoprotecting a macromolecule using tricine
US5919934A (en) * 1997-02-19 1999-07-06 The George Washington University Compounds, compositions, and methods for cancer imaging and therapy
WO1998048699A1 (en) 1997-04-30 1998-11-05 The Board Of Trustees Of The Leland Stanford Junior University Method of imaging cell death in vivo
US6403054B1 (en) 1997-05-28 2002-06-11 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US6844333B1 (en) * 1999-03-26 2005-01-18 The Trustees Of The University Of Pennsylvania Method of treating atherosclerosis
US6686461B1 (en) 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
US7102024B1 (en) 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
AU2001247697B2 (en) * 2000-03-22 2006-06-22 Solulink, Incorporated Hydrazine-based and carbonyl-based bifunctional crosslinking reagents
WO2002080754A2 (en) 2001-04-03 2002-10-17 Theseus Imaging Corporation Methods for using annexin for detecting cell death in vivo and treating associated conditions
WO2002082044A2 (en) 2001-04-03 2002-10-17 The Board Of Trustees Of The Leland Stanford Junior University Method of imaging cell death in vivo
GB0130845D0 (en) * 2001-12-22 2002-02-06 James Peter Analysis
US7158353B2 (en) * 2003-11-06 2007-01-02 Seagate Technology Llc Magnetoresistive sensor having specular sidewall layers
JP5107716B2 (ja) 2004-11-05 2012-12-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 分子治療用生分解性リンカー
AU2012213753B2 (en) * 2011-01-31 2016-09-01 Eth Zurich Trifunctional crosslinking reagents
WO2012167088A1 (en) 2011-06-03 2012-12-06 3M Innovative Properties Company Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom
EP3366311B1 (en) 2011-06-03 2020-02-26 3M Innovative Properties Co. Hydrazino-1h-imidazoquinolin-4-amines and conjugates made therefrom

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
IL93432A (en) * 1989-02-24 1994-02-27 Johnson Mathey Inc Hydrazines and hydrazides, their conjugates with macromolecules, and such conjugates labeled with metallic ions
US5112953A (en) * 1989-12-29 1992-05-12 Neorx Corporation Radiolabeled proteins for diagnostic or therapeutic use

Also Published As

Publication number Publication date
HK1013420A1 (en) 1999-08-27
HUT72332A (en) 1996-04-29
EP0667859B1 (en) 2000-08-23
AU5375594A (en) 1994-05-24
AU676863B2 (en) 1997-03-27
GB9223168D0 (en) 1992-12-16
JPH08502744A (ja) 1996-03-26
ES2150950T3 (es) 2000-12-16
PT667859E (pt) 2001-02-28
KR100295545B1 (ko) 2001-09-17
NO951751L (no) 1995-06-12
HU226459B1 (en) 2008-12-29
NO951751D0 (no) 1995-05-04
ATE195730T1 (de) 2000-09-15
NO305364B1 (no) 1999-05-18
JP3542597B2 (ja) 2004-07-14
FI113044B (fi) 2004-02-27
CA2148595C (en) 2002-05-21
EP0667859A1 (en) 1995-08-23
US5679778A (en) 1997-10-21
WO1994010149A1 (en) 1994-05-11
FI952141A (fi) 1995-05-04
DK0667859T3 (da) 2000-10-16
DE69329293D1 (de) 2000-09-28
KR950704256A (ko) 1995-11-17
DE69329293T2 (de) 2000-12-28
GR3034883T3 (en) 2001-02-28
CA2148595A1 (en) 1994-05-11
NZ257376A (en) 1996-02-27

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Owner name: ANORMED INC.

MA Patent expired