HK1011980A1 - 1-Methylcarbapenem derivatives their preparation and their use as antibiotics - Google Patents

1-Methylcarbapenem derivatives their preparation and their use as antibiotics

Info

Publication number
HK1011980A1
HK1011980A1 HK98113088A HK98113088A HK1011980A1 HK 1011980 A1 HK1011980 A1 HK 1011980A1 HK 98113088 A HK98113088 A HK 98113088A HK 98113088 A HK98113088 A HK 98113088A HK 1011980 A1 HK1011980 A1 HK 1011980A1
Authority
HK
Hong Kong
Prior art keywords
antibiotics
preparation
methylcarbapenem derivatives
compounds
methylcarbapenem
Prior art date
Application number
HK98113088A
Other languages
English (en)
Inventor
Isao Kawamoto
Rokuro Endo
Masao Miyauchi
Katsuhiko Watanabe
Eiji Nakayama
Hiroshi Yasuda
Satoshi Ohya
Yukio Utsui
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HK1011980A1 publication Critical patent/HK1011980A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Cephalosporin Compounds (AREA)
HK98113088A 1991-06-04 1998-12-10 1-Methylcarbapenem derivatives their preparation and their use as antibiotics HK1011980A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP13154591 1991-06-04
JP34573791 1991-12-27
JP3052192 1992-02-18
JP9128392 1992-04-10

Publications (1)

Publication Number Publication Date
HK1011980A1 true HK1011980A1 (en) 1999-07-23

Family

ID=27459269

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113088A HK1011980A1 (en) 1991-06-04 1998-12-10 1-Methylcarbapenem derivatives their preparation and their use as antibiotics

Country Status (21)

Country Link
EP (1) EP0518558B1 (xx)
JP (1) JP2559949B2 (xx)
KR (1) KR100247855B1 (xx)
CN (1) CN1030767C (xx)
AT (1) ATE170521T1 (xx)
AU (1) AU651887B2 (xx)
CA (1) CA2070305A1 (xx)
CZ (1) CZ167792A3 (xx)
DE (1) DE69226815T2 (xx)
DK (1) DK0518558T3 (xx)
ES (1) ES2120992T3 (xx)
FI (1) FI101226B (xx)
HK (1) HK1011980A1 (xx)
HU (2) HU218289B (xx)
IE (1) IE921796A1 (xx)
IL (1) IL102093A (xx)
MX (1) MX9202670A (xx)
NO (1) NO302475B1 (xx)
NZ (1) NZ243022A (xx)
RU (1) RU2093514C1 (xx)
TW (1) TW203612B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
CZ290002B6 (cs) * 1992-03-11 2002-05-15 Sankyo Company Limited Antimikrobiální karbapenemové deriváty, způsob výroby a farmaceutický prostředek
GB9304156D0 (en) * 1992-03-26 1993-04-21 Zeneca Ltd Antibiotic compounds
EP0581502B1 (en) * 1992-07-21 1998-10-21 Zeneca Limited Antibiotic carbapenem compounds
CA2099818A1 (en) * 1992-07-21 1994-01-22 Frederic H. Jung Antibiotic compounds
AU4912393A (en) * 1993-06-15 1994-12-22 Dong Kook Pharmaceutical Co., Ltd. 1-beta-methyl-2-thiolic carbapenem derivatives
JP3848693B2 (ja) * 1994-07-06 2006-11-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規カルバペネム誘導体
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
CA2241092C (en) * 1995-12-21 2004-04-27 Sankyo Company, Limited 1-methylcarbapenem derivatives
DE69714841T2 (de) * 1996-04-26 2003-05-28 Sankyo Co Ein 1-methylcarbapenem-derivat
WO1998007692A1 (en) 1996-08-17 1998-02-26 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
AU1415500A (en) * 1998-12-07 2000-06-26 Sankyo Company Limited 1-methylcarbapenem derivatives
GB9930318D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
GB9930317D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
JP4619655B2 (ja) 2001-09-14 2011-01-26 ハイ・ポイント・ファーマスーティカルズ、エルエルシー 新規アミノアゼチジン、−ピロリジンおよび−ピペリジン誘導体
US6673829B2 (en) 2001-09-14 2004-01-06 Novo Nordisk A/S Aminoazetidine,-pyrrolidine and -piperidine derivatives
CN101367814B (zh) * 2007-06-28 2010-12-15 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰哌啶取代的培南衍生物
US8236792B2 (en) * 2008-05-23 2012-08-07 Janssen Pharmaceutica Nv Substituted pyrrolidine amides as modulators of the histamine H3 receptor
AU2017235293B2 (en) 2016-03-16 2021-02-04 Merck Sharp & Dohme Corp. Carbapenem compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60233076A (ja) * 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
ES2051700T3 (es) * 1986-03-27 1994-07-01 Sumitomo Pharma Un proceso para la preparacion de un compuesto beta-lactama.
CA2036163C (en) * 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production
NO178498C (no) * 1990-02-23 1996-04-10 Sankyo Co Analogifremgangsmåte ved fremstilling av terapeutisk aktive karbapenemderivater
TW198034B (xx) * 1990-03-27 1993-01-11 Manyu Seiyaku Kk
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
CZ290002B6 (cs) * 1992-03-11 2002-05-15 Sankyo Company Limited Antimikrobiální karbapenemové deriváty, způsob výroby a farmaceutický prostředek

Also Published As

Publication number Publication date
IL102093A (en) 1996-12-05
NZ243022A (en) 1993-07-27
FI922561A (fi) 1992-12-05
IL102093A0 (en) 1993-01-14
HU211822A9 (en) 1995-12-28
AU1739092A (en) 1993-03-11
ES2120992T3 (es) 1998-11-16
FI101226B1 (fi) 1998-05-15
FI101226B (fi) 1998-05-15
EP0518558B1 (en) 1998-09-02
CN1069494A (zh) 1993-03-03
DE69226815T2 (de) 1999-05-20
JP2559949B2 (ja) 1996-12-04
RU2093514C1 (ru) 1997-10-20
IE921796A1 (en) 1992-12-16
HU218289B (en) 2000-07-28
TW203612B (xx) 1993-04-11
AU651887B2 (en) 1994-08-04
NO302475B1 (no) 1998-03-09
DK0518558T3 (da) 1999-05-31
JPH05339269A (ja) 1993-12-21
HUT61551A (en) 1993-01-28
CN1030767C (zh) 1996-01-24
KR930000515A (ko) 1993-01-15
FI922561A0 (fi) 1992-06-03
KR100247855B1 (ko) 2000-05-01
DE69226815D1 (de) 1998-10-08
HU9201871D0 (en) 1992-08-28
MX9202670A (es) 1993-01-01
CZ167792A3 (en) 1995-12-13
EP0518558A1 (en) 1992-12-16
NO922185L (no) 1992-12-07
ATE170521T1 (de) 1998-09-15
CA2070305A1 (en) 1992-12-05
NO922185D0 (no) 1992-06-03

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)