HK1005871A1 - Pyrimidine nucleoside derivative - Google Patents

Pyrimidine nucleoside derivative

Info

Publication number
HK1005871A1
HK1005871A1 HK98104955A HK98104955A HK1005871A1 HK 1005871 A1 HK1005871 A1 HK 1005871A1 HK 98104955 A HK98104955 A HK 98104955A HK 98104955 A HK98104955 A HK 98104955A HK 1005871 A1 HK1005871 A1 HK 1005871A1
Authority
HK
Hong Kong
Prior art keywords
pyrimidine nucleoside
nucleoside derivative
hydroxy
hydrogen
represent
Prior art date
Application number
HK98104955A
Other languages
English (en)
Inventor
Akira Matsuda
Takuma Sasaki
Tohru Ueda
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HK1005871A1 publication Critical patent/HK1005871A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK98104955A 1990-06-15 1998-06-05 Pyrimidine nucleoside derivative HK1005871A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15668890 1990-06-15

Publications (1)

Publication Number Publication Date
HK1005871A1 true HK1005871A1 (en) 1999-01-29

Family

ID=15633157

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104955A HK1005871A1 (en) 1990-06-15 1998-06-05 Pyrimidine nucleoside derivative

Country Status (13)

Country Link
US (2) US5616567A (xx)
EP (1) EP0535231B1 (xx)
JP (1) JP2559917B2 (xx)
KR (1) KR970011306B1 (xx)
AT (1) ATE122041T1 (xx)
CA (1) CA2085345C (xx)
DE (1) DE69109482T2 (xx)
DK (1) DK0535231T3 (xx)
ES (1) ES2074719T3 (xx)
HK (1) HK1005871A1 (xx)
HU (1) HU218924B (xx)
RU (1) RU2116306C1 (xx)
WO (1) WO1991019713A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI105556B (fi) * 1991-09-30 2000-09-15 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta
KR20030036189A (ko) * 2000-05-26 2003-05-09 이데닉스(케이만)리미티드 플라비바이러스 및 페스티바이러스의 치료방법 및 조성물
MY142304A (en) * 2005-01-31 2010-11-15 Taiho Pharmaceutical Co Ltd Novel pyrimidine nucleoside compound or salt thereof
GB0523041D0 (en) * 2005-11-11 2005-12-21 Cyclacel Ltd Combination
WO2008010571A1 (fr) 2006-07-21 2008-01-24 Taiho Pharmaceutical Co., Ltd. Composé nucléosidique de 2'cyanopyrimidine
GB0625283D0 (en) 2006-12-19 2007-01-24 Cyclacel Ltd Combination
RU2488591C2 (ru) * 2007-09-26 2013-07-27 Маунт Синай Скул Оф Медсин Аналоги азацитидина и их применение
US8124593B2 (en) 2007-11-05 2012-02-28 Cyclacel Limited Methods of treatment using sapacitabine
US7863255B2 (en) * 2008-04-29 2011-01-04 Taiho Pharmaceutical Co., Ltd. Methods of administering antitumor agent comprising deoxycytidine derivative
GB0808359D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
GB0808357D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
CA2725295C (en) 2008-06-09 2016-11-08 Cyclacel Limited Combination of sapacitabine (cndac) and dna methyltransferase inhibitors such as decitabine and procaine
DK2431376T4 (da) * 2009-05-15 2024-02-26 Delta Fly Pharma Inc Ny stabilt krystal af 1-(2'-cyano-2'-deoxy-ß-D-arabinofuranosyl)cytosinmonohydrochlorid
EP2696878B1 (en) 2011-04-14 2019-07-10 Cyclacel Limited Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia
CN104114568B (zh) 2011-12-22 2017-09-01 艾丽奥斯生物制药有限公司 取代的核苷、核苷酸及其类似物
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
JP6286421B2 (ja) 2012-05-15 2018-02-28 サイクラセル リミテッド サパシタビン及びセリシクリブの投与レジメン
WO2019081951A1 (en) 2017-10-27 2019-05-02 Cyclacel Limited DOSAGE REGIME
US11957701B2 (en) 2020-07-17 2024-04-16 Delta-Fly Pharma, Inc. Therapy and new therapeutic agent for blood cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2007094A6 (es) * 1987-07-29 1989-06-01 Consejo Superior Investigacion Procedimiento para la preparacion de 3 -c- ciano-2,3 -didesoxinucleosido.

Also Published As

Publication number Publication date
KR970011306B1 (ko) 1997-07-09
EP0535231A4 (en) 1993-06-30
CA2085345C (en) 2001-08-07
CA2085345A1 (en) 1991-12-16
KR930700485A (ko) 1993-03-15
JPH04235182A (ja) 1992-08-24
HU218924B (hu) 2000-12-28
ES2074719T3 (es) 1995-09-16
JP2559917B2 (ja) 1996-12-04
DE69109482T2 (de) 1996-02-15
US5616567A (en) 1997-04-01
RU2116306C1 (ru) 1998-07-27
DK0535231T3 (da) 1995-08-21
HUT62582A (en) 1993-05-28
US5654420A (en) 1997-08-05
DE69109482D1 (en) 1995-06-08
HU9203967D0 (en) 1993-03-29
EP0535231A1 (en) 1993-04-07
ATE122041T1 (de) 1995-05-15
WO1991019713A1 (en) 1991-12-26
EP0535231B1 (en) 1995-05-03

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20110612