DK0424899T3 - Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf - Google Patents
Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK0424899T3 DK0424899T3 DK90120373.7T DK90120373T DK0424899T3 DK 0424899 T3 DK0424899 T3 DK 0424899T3 DK 90120373 T DK90120373 T DK 90120373T DK 0424899 T3 DK0424899 T3 DK 0424899T3
- Authority
- DK
- Denmark
- Prior art keywords
- processes
- preparation
- new
- hydrogen atom
- glycoside derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019890015375A KR0157612B1 (ko) | 1989-10-25 | 1989-10-25 | 신규 안트라사이클린 글리코사이드 유도체 |
KR1019900016213A KR920008062A (ko) | 1990-10-13 | 1990-10-13 | 신규 안트라사이클린 클리코사이드 유도체 및 그 제조방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0424899T3 true DK0424899T3 (da) | 1997-03-24 |
Family
ID=26628106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90120373.7T DK0424899T3 (da) | 1989-10-25 | 1990-10-24 | Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf |
Country Status (10)
Country | Link |
---|---|
US (1) | US5220001A (da) |
EP (1) | EP0424899B1 (da) |
JP (1) | JP2806621B2 (da) |
CN (1) | CN1028997C (da) |
AT (1) | ATE148128T1 (da) |
CA (1) | CA2028465C (da) |
DE (1) | DE69029781T2 (da) |
DK (1) | DK0424899T3 (da) |
ES (1) | ES2096572T3 (da) |
GR (1) | GR3022702T3 (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143864A (en) * | 1994-06-28 | 2000-11-07 | Merck & Co., Inc. | Peptides |
US5866679A (en) * | 1994-06-28 | 1999-02-02 | Merck & Co., Inc. | Peptides |
AU694546C (en) * | 1994-08-19 | 2001-09-06 | La Region Wallonne | Compounds, pharmaceutical composition and diagnostic device comprising same and their use |
EP0761678B1 (en) * | 1995-09-08 | 1999-03-31 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof |
US5998362A (en) * | 1996-09-12 | 1999-12-07 | Merck & Co., Inc. | Conjugates useful in the treatment of prostate cancer |
US6391305B1 (en) | 1997-09-10 | 2002-05-21 | Merck & Co., Inc. | Conjugates useful in the treatment of prostate cancer |
US7425541B2 (en) * | 1998-12-11 | 2008-09-16 | Medarex, Inc. | Enzyme-cleavable prodrug compounds |
GB0012718D0 (en) * | 2000-05-24 | 2000-07-19 | Angeletti P Ist Richerche Bio | Conjugates of aminodrugs |
JP2004510702A (ja) | 2000-06-14 | 2004-04-08 | メダレックス,インコーポレイティド | イソロイシンを有するプロドラッグ化合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1533151A (fr) * | 1962-05-18 | 1968-07-19 | Rhone Poulenc Sa | Nouvel antibiotique et sa préparation |
YU33730B (en) * | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
FR2135221A1 (en) * | 1971-05-04 | 1972-12-15 | Farmaceutici Italia | Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid |
CA1248944A (en) * | 1982-09-28 | 1989-01-17 | Gareth J. Thomas | Anthracycline glycosides |
US4870058A (en) * | 1982-12-20 | 1989-09-26 | Ohio State University Research Foundation | 14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics |
JPH0631298B2 (ja) * | 1985-12-18 | 1994-04-27 | 財団法人微生物化学研究会 | 新規アンスラサイクリン誘導体,抗腫瘍剤,及び製造法 |
JPH0742304B2 (ja) * | 1986-12-05 | 1995-05-10 | 財団法人微生物化学研究会 | 新規なアンスラサイクリン誘導体およびその製造法 |
EP0335369A3 (en) * | 1988-03-29 | 1990-03-28 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | New anthracycline derivatives and processes for the preparation of the same |
-
1990
- 1990-10-22 US US07/600,708 patent/US5220001A/en not_active Expired - Fee Related
- 1990-10-24 AT AT90120373T patent/ATE148128T1/de not_active IP Right Cessation
- 1990-10-24 CA CA002028465A patent/CA2028465C/en not_active Expired - Fee Related
- 1990-10-24 JP JP2284513A patent/JP2806621B2/ja not_active Expired - Fee Related
- 1990-10-24 DE DE69029781T patent/DE69029781T2/de not_active Expired - Fee Related
- 1990-10-24 DK DK90120373.7T patent/DK0424899T3/da active
- 1990-10-24 ES ES90120373T patent/ES2096572T3/es not_active Expired - Lifetime
- 1990-10-24 EP EP90120373A patent/EP0424899B1/en not_active Expired - Lifetime
- 1990-10-25 CN CN90109514A patent/CN1028997C/zh not_active Expired - Fee Related
-
1997
- 1997-02-27 GR GR970400389T patent/GR3022702T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0424899B1 (en) | 1997-01-22 |
JP2806621B2 (ja) | 1998-09-30 |
EP0424899A2 (en) | 1991-05-02 |
CN1052865A (zh) | 1991-07-10 |
ES2096572T3 (es) | 1997-03-16 |
CA2028465A1 (en) | 1991-04-26 |
CA2028465C (en) | 1999-06-08 |
EP0424899A3 (en) | 1991-09-18 |
ATE148128T1 (de) | 1997-02-15 |
CN1028997C (zh) | 1995-06-21 |
GR3022702T3 (en) | 1997-05-31 |
JPH03206095A (ja) | 1991-09-09 |
DE69029781T2 (de) | 1997-05-15 |
DE69029781D1 (de) | 1997-03-06 |
US5220001A (en) | 1993-06-15 |
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