DK0424899T3 - Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf - Google Patents

Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0424899T3
DK0424899T3 DK90120373.7T DK90120373T DK0424899T3 DK 0424899 T3 DK0424899 T3 DK 0424899T3 DK 90120373 T DK90120373 T DK 90120373T DK 0424899 T3 DK0424899 T3 DK 0424899T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
new
hydrogen atom
glycoside derivatives
Prior art date
Application number
DK90120373.7T
Other languages
English (en)
Inventor
Dae Ok Kwang
Bae Park Jeong
Sung Kim Moon
Original Assignee
Zaidan Hojin Biseibutsu
Dong A Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019890015375A external-priority patent/KR0157612B1/ko
Priority claimed from KR1019900016213A external-priority patent/KR920008062A/ko
Application filed by Zaidan Hojin Biseibutsu, Dong A Pharm Co Ltd filed Critical Zaidan Hojin Biseibutsu
Application granted granted Critical
Publication of DK0424899T3 publication Critical patent/DK0424899T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK90120373.7T 1989-10-25 1990-10-24 Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf DK0424899T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019890015375A KR0157612B1 (ko) 1989-10-25 1989-10-25 신규 안트라사이클린 글리코사이드 유도체
KR1019900016213A KR920008062A (ko) 1990-10-13 1990-10-13 신규 안트라사이클린 클리코사이드 유도체 및 그 제조방법

Publications (1)

Publication Number Publication Date
DK0424899T3 true DK0424899T3 (da) 1997-03-24

Family

ID=26628106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90120373.7T DK0424899T3 (da) 1989-10-25 1990-10-24 Hidtil ukendte anthracyclinglycosidderivater og fremgangsmåde til fremstilling deraf

Country Status (10)

Country Link
US (1) US5220001A (da)
EP (1) EP0424899B1 (da)
JP (1) JP2806621B2 (da)
CN (1) CN1028997C (da)
AT (1) ATE148128T1 (da)
CA (1) CA2028465C (da)
DE (1) DE69029781T2 (da)
DK (1) DK0424899T3 (da)
ES (1) ES2096572T3 (da)
GR (1) GR3022702T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
AU694546C (en) * 1994-08-19 2001-09-06 La Region Wallonne Compounds, pharmaceutical composition and diagnostic device comprising same and their use
EP0761678B1 (en) * 1995-09-08 1999-03-31 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
GB0012718D0 (en) * 2000-05-24 2000-07-19 Angeletti P Ist Richerche Bio Conjugates of aminodrugs
JP2004510702A (ja) 2000-06-14 2004-04-08 メダレックス，インコーポレイティド イソロイシンを有するプロドラッグ化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1533151A (fr) * 1962-05-18 1968-07-19 Rhone Poulenc Sa Nouvel antibiotique et sa préparation
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
FR2135221A1 (en) * 1971-05-04 1972-12-15 Farmaceutici Italia Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
US4870058A (en) * 1982-12-20 1989-09-26 Ohio State University Research Foundation 14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics
JPH0631298B2 (ja) * 1985-12-18 1994-04-27 財団法人微生物化学研究会 新規アンスラサイクリン誘導体，抗腫瘍剤，及び製造法
JPH0742304B2 (ja) * 1986-12-05 1995-05-10 財団法人微生物化学研究会 新規なアンスラサイクリン誘導体およびその製造法
EP0335369A3 (en) * 1988-03-29 1990-03-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai New anthracycline derivatives and processes for the preparation of the same

Also Published As

Publication number Publication date
EP0424899B1 (en) 1997-01-22
JP2806621B2 (ja) 1998-09-30
EP0424899A2 (en) 1991-05-02
CN1052865A (zh) 1991-07-10
ES2096572T3 (es) 1997-03-16
CA2028465A1 (en) 1991-04-26
CA2028465C (en) 1999-06-08
EP0424899A3 (en) 1991-09-18
ATE148128T1 (de) 1997-02-15
CN1028997C (zh) 1995-06-21
GR3022702T3 (en) 1997-05-31
JPH03206095A (ja) 1991-09-09
DE69029781T2 (de) 1997-05-15
DE69029781D1 (de) 1997-03-06
US5220001A (en) 1993-06-15

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