DK0535231T3 - Pyrimidinnucleosid-derivater - Google Patents
Pyrimidinnucleosid-derivaterInfo
- Publication number
- DK0535231T3 DK0535231T3 DK91911192.2T DK91911192T DK0535231T3 DK 0535231 T3 DK0535231 T3 DK 0535231T3 DK 91911192 T DK91911192 T DK 91911192T DK 0535231 T3 DK0535231 T3 DK 0535231T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrimidine nucleoside
- nucleoside derivatives
- hydroxy
- hydrogen
- represent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15668890 | 1990-06-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0535231T3 true DK0535231T3 (da) | 1995-08-21 |
Family
ID=15633157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91911192.2T DK0535231T3 (da) | 1990-06-15 | 1991-06-13 | Pyrimidinnucleosid-derivater |
Country Status (13)
Country | Link |
---|---|
US (2) | US5616567A (da) |
EP (1) | EP0535231B1 (da) |
JP (1) | JP2559917B2 (da) |
KR (1) | KR970011306B1 (da) |
AT (1) | ATE122041T1 (da) |
CA (1) | CA2085345C (da) |
DE (1) | DE69109482T2 (da) |
DK (1) | DK0535231T3 (da) |
ES (1) | ES2074719T3 (da) |
HK (1) | HK1005871A1 (da) |
HU (1) | HU218924B (da) |
RU (1) | RU2116306C1 (da) |
WO (1) | WO1991019713A1 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2079413C (en) * | 1991-09-30 | 2003-09-09 | Masakatsu Kaneko | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use |
EA200601591A1 (ru) * | 2000-05-26 | 2007-02-27 | Айденикс (Кайман) Лимитед | Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций |
MY142304A (en) | 2005-01-31 | 2010-11-15 | Taiho Pharmaceutical Co Ltd | Novel pyrimidine nucleoside compound or salt thereof |
GB0523041D0 (en) * | 2005-11-11 | 2005-12-21 | Cyclacel Ltd | Combination |
JPWO2008010571A1 (ja) * | 2006-07-21 | 2009-12-17 | 大鵬薬品工業株式会社 | 2’−シアノピリミジンヌクレオシド化合物 |
GB0625283D0 (en) | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
MX2010003261A (es) * | 2007-09-26 | 2010-08-18 | Sinai School Medicine | Analogos de azacitidina y usos de los mismos. |
US8124593B2 (en) | 2007-11-05 | 2012-02-28 | Cyclacel Limited | Methods of treatment using sapacitabine |
US7863255B2 (en) * | 2008-04-29 | 2011-01-04 | Taiho Pharmaceutical Co., Ltd. | Methods of administering antitumor agent comprising deoxycytidine derivative |
GB0808359D0 (en) * | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
GB0808357D0 (en) * | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
NZ589719A (en) | 2008-06-09 | 2012-08-31 | Cyclacel Ltd | Combinations of sapacitabine or cndac with dna methyltransferase inhibitors such as decitabine and procaine |
CN102414216B (zh) * | 2009-05-15 | 2015-01-21 | 德鲁塔负富莱制药股份有限公司 | 1-(2’-氰基-2’-脱氧-β-D-阿拉伯呋喃糖基)胞嘧啶一盐酸盐的稳定型结晶 |
US10226478B2 (en) | 2011-04-14 | 2019-03-12 | Cyclacel Limited | Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia |
DK2794627T3 (da) | 2011-12-22 | 2019-01-14 | Alios Biopharma Inc | Substituerede nukleosider, nukleotider og analoger deraf |
USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
US9872874B2 (en) | 2012-05-15 | 2018-01-23 | Cyclacel Limited | Dosage regimen for sapacitabine and seliciclib |
WO2019081951A1 (en) | 2017-10-27 | 2019-05-02 | Cyclacel Limited | DOSAGE REGIME |
EP4183397A4 (en) | 2020-07-17 | 2024-03-27 | Delta Fly Pharma Inc | NEW THERAPY AND NEW THERAPEUTIC FOR BLOOD CANCER |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2007094A6 (es) * | 1987-07-29 | 1989-06-01 | Consejo Superior Investigacion | Procedimiento para la preparacion de 3 -c- ciano-2,3 -didesoxinucleosido. |
-
1991
- 1991-06-11 JP JP3138859A patent/JP2559917B2/ja not_active Expired - Lifetime
- 1991-06-13 AT AT91911192T patent/ATE122041T1/de not_active IP Right Cessation
- 1991-06-13 ES ES91911192T patent/ES2074719T3/es not_active Expired - Lifetime
- 1991-06-13 KR KR1019920703246A patent/KR970011306B1/ko not_active IP Right Cessation
- 1991-06-13 DK DK91911192.2T patent/DK0535231T3/da active
- 1991-06-13 WO PCT/JP1991/000797 patent/WO1991019713A1/ja active IP Right Grant
- 1991-06-13 DE DE69109482T patent/DE69109482T2/de not_active Expired - Lifetime
- 1991-06-13 CA CA002085345A patent/CA2085345C/en not_active Expired - Lifetime
- 1991-06-13 RU RU92016591/04A patent/RU2116306C1/ru active
- 1991-06-13 HU HU9203967A patent/HU218924B/hu unknown
- 1991-06-13 EP EP91911192A patent/EP0535231B1/en not_active Expired - Lifetime
-
1994
- 1994-09-07 US US08/301,720 patent/US5616567A/en not_active Expired - Lifetime
-
1995
- 1995-06-01 US US08/457,510 patent/US5654420A/en not_active Expired - Lifetime
-
1998
- 1998-06-05 HK HK98104955A patent/HK1005871A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1005871A1 (en) | 1999-01-29 |
HUT62582A (en) | 1993-05-28 |
ATE122041T1 (de) | 1995-05-15 |
US5616567A (en) | 1997-04-01 |
CA2085345C (en) | 2001-08-07 |
HU218924B (hu) | 2000-12-28 |
WO1991019713A1 (en) | 1991-12-26 |
KR970011306B1 (ko) | 1997-07-09 |
EP0535231B1 (en) | 1995-05-03 |
RU2116306C1 (ru) | 1998-07-27 |
JP2559917B2 (ja) | 1996-12-04 |
JPH04235182A (ja) | 1992-08-24 |
KR930700485A (ko) | 1993-03-15 |
CA2085345A1 (en) | 1991-12-16 |
DE69109482D1 (en) | 1995-06-08 |
EP0535231A1 (en) | 1993-04-07 |
EP0535231A4 (en) | 1993-06-30 |
US5654420A (en) | 1997-08-05 |
ES2074719T3 (es) | 1995-09-16 |
DE69109482T2 (de) | 1996-02-15 |
HU9203967D0 (en) | 1993-03-29 |
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