DE3851179D1 - Oxetanocin. - Google Patents

Oxetanocin.

Info

Publication number
DE3851179D1
DE3851179D1 DE3851179T DE3851179T DE3851179D1 DE 3851179 D1 DE3851179 D1 DE 3851179D1 DE 3851179 T DE3851179 T DE 3851179T DE 3851179 T DE3851179 T DE 3851179T DE 3851179 D1 DE3851179 D1 DE 3851179D1
Authority
DE
Germany
Prior art keywords
chem
oxetanocin
represented
oxetanocins
immunosuppressive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3851179T
Other languages
English (en)
Other versions
DE3851179T2 (de
Inventor
Nobuyoshi Shimada
Shigeru Hasegawa
Takayuki Tomizawa
Seiichi Saito
Kyoichi Shibuya
Akio Fujii
Hiroo Hoshino
Kenichi Matsubara
Takemitsu Nagahata
Katsutoshi Takahashi
Yukihiro Nishiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP27326687A external-priority patent/JPH01117830A/ja
Priority claimed from JP31228087A external-priority patent/JPH01153637A/ja
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Application granted granted Critical
Publication of DE3851179D1 publication Critical patent/DE3851179D1/de
Publication of DE3851179T2 publication Critical patent/DE3851179T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
DE3851179T 1987-05-19 1988-05-17 Oxetanocin. Expired - Fee Related DE3851179T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12015987 1987-05-19
JP27326687A JPH01117830A (ja) 1987-10-30 1987-10-30 抗サイトメガロウイルス剤
JP31228087A JPH01153637A (ja) 1987-12-11 1987-12-11 Ｂ型肝炎ウイルス抑制剤

Publications (2)

Publication Number Publication Date
DE3851179D1 true DE3851179D1 (de) 1994-09-29
DE3851179T2 DE3851179T2 (de) 1994-12-15

Family

ID=27313981

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851179T Expired - Fee Related DE3851179T2 (de) 1987-05-19 1988-05-17 Oxetanocin.

Country Status (10)

Country Link
EP (1) EP0291917B1 (de)
KR (1) KR880013937A (de)
CN (1) CN1017153B (de)
AT (1) ATE110382T1 (de)
AU (1) AU599232B2 (de)
CA (1) CA1304365C (de)
DE (1) DE3851179T2 (de)
DK (1) DK271388A (de)
HU (1) HUT47128A (de)
IL (1) IL86381A0 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62208295A (ja) * 1986-03-07 1987-09-12 Nippon Kayaku Co Ltd ヒポキサンチン塩基を有する新規化合物およびその製造法
US5214048A (en) * 1987-05-19 1993-05-25 Nippon Kayaku Kabushiki Kaisha Oxetanocins
US5420276A (en) * 1987-11-03 1995-05-30 Abbott Laboratories Analogs of oxetanyl purines and pyrimidines
US5597824A (en) * 1987-11-03 1997-01-28 Abbott Laboratories Analogs of oxetanyl purines and pyrimidines
US5041447A (en) * 1988-03-23 1991-08-20 Nippon Kayaku Kabushiki Kaisha Oxetanocin-related compounds and pharmaceutical compositions containing them
US5179084A (en) * 1989-04-10 1993-01-12 Nippon Kayaku Kabushiki Kaisha Antiviral phosphoric acid esters of oxetanocins
US5164500A (en) * 1989-04-20 1992-11-17 Nippon Kayaku Kabushiki Kaisha Oxetanocin G
US4992368A (en) * 1989-04-20 1991-02-12 Nippon Kayaku Kabushiki Kaisha Novel process for producing oxetanocin G
US5164520A (en) * 1989-04-24 1992-11-17 E. R. Squibb & Sons, Inc. Intermediates for purinyl and pyrimidinyl tetrahydrofurans
US5145960A (en) * 1989-04-24 1992-09-08 E. R. Squibb & Sons, Inc. Pyrimidinyl tetrahydrofurans
US4988703A (en) * 1989-05-22 1991-01-29 Abbott Laboratories Carbocyclic nucleoside analogs with antiviral activity
JPH03173896A (ja) * 1989-09-08 1991-07-29 Nippon Kayaku Co Ltd 新規オキセタノシン誘導体、その塩およびその用途
US5202459A (en) * 1989-11-07 1993-04-13 Nippon Kayaku Kabushiki Kaisha Process for producing cyclobutane derivative
JPH03167125A (ja) * 1989-11-27 1991-07-19 Nippon Kayaku Co Ltd 抗水痘―帯状疱疹ウイルス剤
IE904378A1 (en) 1989-12-20 1991-07-03 Abbott Lab Analogs of oxetanyl purines and pyrimidines
US5324730A (en) * 1990-05-24 1994-06-28 Nippon Kayaku Kabushiki Kaisha Phenoxyphosphoryloxymethyl cyclobutyl purines
JPH0446192A (ja) * 1990-06-12 1992-02-17 Nippon Kayaku Co Ltd オキセタノシンｇ無水物結晶及びその製造法
AU647822B2 (en) * 1990-09-14 1994-03-31 Marion Merrell Dow Inc. Novel carbocyclic adenosine analogs useful as immunosuppressants
US5514688A (en) * 1990-09-14 1996-05-07 Merrell Dow Pharmaceuticals Inc. Carbocyclic adenosine analogs useful as immunosuppressants
US5283331A (en) * 1990-12-20 1994-02-01 Nippon Kayaku Kabushiki Kaisha 2-halogeno-oxetanocin A and phosphoric ester thereof
JPH0559085A (ja) * 1990-12-27 1993-03-09 Nippon Kayaku Co Ltd イミダゾール塩基を有するオキセタノシン誘導体
GB9424842D0 (en) * 1994-12-09 1995-02-08 British Tech Group Pharmaceutical compositions
AU2004293423A1 (en) 2003-11-21 2005-06-09 University Of Connecticut Heterocyclyl-substituted oxetanes for the treatment of proliferative or infectious diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528311B1 (fr) * 1982-06-14 1985-06-14 Synthelabo Compositions pharmaceutiques a base de xylosides et lyxosides de bases puriques et pyrimidiques
US4743689A (en) * 1984-11-20 1988-05-10 Nippon Kayaku Kabushiki Kaisha Antibiotic derivative of adenine
ATE190064T1 (de) * 1985-09-17 2000-03-15 Wellcome Found Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten.
GB8708050D0 (en) * 1987-04-03 1987-05-07 Wellcome Found Therapeutic nucleosides
US5041447A (en) * 1988-03-23 1991-08-20 Nippon Kayaku Kabushiki Kaisha Oxetanocin-related compounds and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL86381A0 (en) 1988-11-15
EP0291917A2 (de) 1988-11-23
DK271388D0 (da) 1988-05-18
AU1639888A (en) 1988-11-24
CA1304365C (en) 1992-06-30
CN1017153B (zh) 1992-06-24
KR880013937A (ko) 1988-12-22
ATE110382T1 (de) 1994-09-15
DE3851179T2 (de) 1994-12-15
CN88102932A (zh) 1988-12-21
EP0291917B1 (de) 1994-08-24
HUT47128A (en) 1989-01-30
DK271388A (da) 1988-11-20
AU599232B2 (en) 1990-07-12
EP0291917A3 (en) 1990-12-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee