HK1005871A1 - Pyrimidine nucleoside derivative - Google Patents
Pyrimidine nucleoside derivativeInfo
- Publication number
- HK1005871A1 HK1005871A1 HK98104955A HK98104955A HK1005871A1 HK 1005871 A1 HK1005871 A1 HK 1005871A1 HK 98104955 A HK98104955 A HK 98104955A HK 98104955 A HK98104955 A HK 98104955A HK 1005871 A1 HK1005871 A1 HK 1005871A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrimidine nucleoside
- nucleoside derivative
- hydroxy
- hydrogen
- represent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15668890 | 1990-06-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1005871A1 true HK1005871A1 (en) | 1999-01-29 |
Family
ID=15633157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98104955A HK1005871A1 (en) | 1990-06-15 | 1998-06-05 | Pyrimidine nucleoside derivative |
Country Status (13)
Country | Link |
---|---|
US (2) | US5616567A (ja) |
EP (1) | EP0535231B1 (ja) |
JP (1) | JP2559917B2 (ja) |
KR (1) | KR970011306B1 (ja) |
AT (1) | ATE122041T1 (ja) |
CA (1) | CA2085345C (ja) |
DE (1) | DE69109482T2 (ja) |
DK (1) | DK0535231T3 (ja) |
ES (1) | ES2074719T3 (ja) |
HK (1) | HK1005871A1 (ja) |
HU (1) | HU218924B (ja) |
RU (1) | RU2116306C1 (ja) |
WO (1) | WO1991019713A1 (ja) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2079413C (en) * | 1991-09-30 | 2003-09-09 | Masakatsu Kaneko | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use |
NZ547204A (en) * | 2000-05-26 | 2008-01-31 | Idenix Cayman Ltd | Methods and compositions for treating flaviviruses and pestiviruses |
TW200637870A (en) * | 2005-01-31 | 2006-11-01 | Taiho Pharmaceutical Co Ltd | Novel pyrimidine nucleoside compound and salt thereof |
GB0523041D0 (en) * | 2005-11-11 | 2005-12-21 | Cyclacel Ltd | Combination |
TW200817426A (en) | 2006-07-21 | 2008-04-16 | Taiho Pharmaceutical Co Ltd | 2'-cyanopyrimidine nucleoside compound |
GB0625283D0 (en) | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
KR20100072230A (ko) * | 2007-09-26 | 2010-06-30 | 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 | 아자시티딘 유사체 및 이의 용도 |
US8124593B2 (en) | 2007-11-05 | 2012-02-28 | Cyclacel Limited | Methods of treatment using sapacitabine |
US7863255B2 (en) | 2008-04-29 | 2011-01-04 | Taiho Pharmaceutical Co., Ltd. | Methods of administering antitumor agent comprising deoxycytidine derivative |
GB0808359D0 (en) * | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
GB0808357D0 (en) * | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
NZ589719A (en) | 2008-06-09 | 2012-08-31 | Cyclacel Ltd | Combinations of sapacitabine or cndac with dna methyltransferase inhibitors such as decitabine and procaine |
DK2431376T4 (da) * | 2009-05-15 | 2024-02-26 | Delta Fly Pharma Inc | Ny stabilt krystal af 1-(2'-cyano-2'-deoxy-ß-D-arabinofuranosyl)cytosinmonohydrochlorid |
WO2012140436A1 (en) | 2011-04-14 | 2012-10-18 | Cyclacel Limited | Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia |
HUE041509T2 (hu) | 2011-12-22 | 2019-05-28 | Janssen Biopharma Inc | Szubsztituált nukleozidok, nukleotidok és ezek analógjai |
US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
JP6286421B2 (ja) | 2012-05-15 | 2018-02-28 | サイクラセル リミテッド | サパシタビン及びセリシクリブの投与レジメン |
WO2019081951A1 (en) | 2017-10-27 | 2019-05-02 | Cyclacel Limited | DOSAGE REGIME |
US11957701B2 (en) | 2020-07-17 | 2024-04-16 | Delta-Fly Pharma, Inc. | Therapy and new therapeutic agent for blood cancer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2007094A6 (es) * | 1987-07-29 | 1989-06-01 | Consejo Superior Investigacion | Procedimiento para la preparacion de 3 -c- ciano-2,3 -didesoxinucleosido. |
-
1991
- 1991-06-11 JP JP3138859A patent/JP2559917B2/ja not_active Expired - Lifetime
- 1991-06-13 KR KR1019920703246A patent/KR970011306B1/ko not_active IP Right Cessation
- 1991-06-13 HU HU9203967A patent/HU218924B/hu unknown
- 1991-06-13 DK DK91911192.2T patent/DK0535231T3/da active
- 1991-06-13 DE DE69109482T patent/DE69109482T2/de not_active Expired - Lifetime
- 1991-06-13 ES ES91911192T patent/ES2074719T3/es not_active Expired - Lifetime
- 1991-06-13 CA CA002085345A patent/CA2085345C/en not_active Expired - Lifetime
- 1991-06-13 AT AT91911192T patent/ATE122041T1/de not_active IP Right Cessation
- 1991-06-13 EP EP91911192A patent/EP0535231B1/en not_active Expired - Lifetime
- 1991-06-13 WO PCT/JP1991/000797 patent/WO1991019713A1/ja active IP Right Grant
- 1991-06-13 RU RU92016591/04A patent/RU2116306C1/ru active
-
1994
- 1994-09-07 US US08/301,720 patent/US5616567A/en not_active Expired - Lifetime
-
1995
- 1995-06-01 US US08/457,510 patent/US5654420A/en not_active Expired - Lifetime
-
1998
- 1998-06-05 HK HK98104955A patent/HK1005871A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2085345C (en) | 2001-08-07 |
EP0535231B1 (en) | 1995-05-03 |
HUT62582A (en) | 1993-05-28 |
JPH04235182A (ja) | 1992-08-24 |
HU218924B (hu) | 2000-12-28 |
US5654420A (en) | 1997-08-05 |
ES2074719T3 (es) | 1995-09-16 |
WO1991019713A1 (en) | 1991-12-26 |
HU9203967D0 (en) | 1993-03-29 |
EP0535231A4 (en) | 1993-06-30 |
KR930700485A (ko) | 1993-03-15 |
ATE122041T1 (de) | 1995-05-15 |
DE69109482D1 (en) | 1995-06-08 |
EP0535231A1 (en) | 1993-04-07 |
CA2085345A1 (en) | 1991-12-16 |
KR970011306B1 (ko) | 1997-07-09 |
US5616567A (en) | 1997-04-01 |
RU2116306C1 (ru) | 1998-07-27 |
DK0535231T3 (da) | 1995-08-21 |
JP2559917B2 (ja) | 1996-12-04 |
DE69109482T2 (de) | 1996-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20110612 |