HK1000467A1 - Analogues of the 15- deoxyspergualin process for their preparation and their use as immunosuppresants - Google Patents

Analogues of the 15- deoxyspergualin process for their preparation and their use as immunosuppresants

Info

Publication number
HK1000467A1
HK1000467A1 HK97102083A HK97102083A HK1000467A1 HK 1000467 A1 HK1000467 A1 HK 1000467A1 HK 97102083 A HK97102083 A HK 97102083A HK 97102083 A HK97102083 A HK 97102083A HK 1000467 A1 HK1000467 A1 HK 1000467A1
Authority
HK
Hong Kong
Prior art keywords
immunosuppresants
deoxyspergualin
analogues
preparation
compounds
Prior art date
Application number
HK97102083A
Other languages
English (en)
Inventor
Renaut Patrice
Lebreton Luc
Dutartre Patrick
Derrepas Philippe
Samreth Soth
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of HK1000467A1 publication Critical patent/HK1000467A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK97102083A 1992-12-02 1997-11-04 Analogues of the 15- deoxyspergualin process for their preparation and their use as immunosuppresants HK1000467A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
HK1000467A1 true HK1000467A1 (en) 1998-03-27

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97102083A HK1000467A1 (en) 1992-12-02 1997-11-04 Analogues of the 15- deoxyspergualin process for their preparation and their use as immunosuppresants

Country Status (24)

Country Link
US (1) US5476870A (ko)
EP (1) EP0600762B1 (ko)
JP (1) JP2945261B2 (ko)
KR (1) KR100187328B1 (ko)
CN (1) CN1045431C (ko)
AT (1) ATE140215T1 (ko)
AU (1) AU664124B2 (ko)
CA (1) CA2110437C (ko)
CZ (1) CZ284958B6 (ko)
DE (1) DE69303583T2 (ko)
DK (1) DK0600762T3 (ko)
ES (1) ES2092263T3 (ko)
FI (1) FI112211B (ko)
FR (1) FR2698628B1 (ko)
GR (1) GR3021269T3 (ko)
HK (1) HK1000467A1 (ko)
HU (1) HU218908B (ko)
NO (1) NO180483C (ko)
NZ (1) NZ250330A (ko)
RU (1) RU2114823C1 (ko)
SK (1) SK280286B6 (ko)
TW (1) TW311132B (ko)
UA (1) UA39920C2 (ko)
ZA (1) ZA938821B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69600780T2 (de) * 1995-02-10 1999-05-27 Fournier Ind & Sante 15-deoxyspergualin-analoge verbindungen, ihre verwendung als therapeutika und verfahren zu ihrer herstellung
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
ES2170042T3 (es) * 1998-08-28 2004-10-01 Gryphon Therapeutics, Inc. Procedimiento para la preparacion de cadenas de poliamida de longitud precisa y sus conjugados con proteinas.
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
AU2005237764B2 (en) 2004-05-05 2011-11-24 Silence Therapeutics Gmbh Lipids, lipid complexes and use thereof
EP2992902A1 (en) 2004-12-27 2016-03-09 Silence Therapeutics GmbH Lipid complexes coated with peg and their uses
EP2269980A4 (de) 2008-12-24 2011-05-18 Vertex Closed Joint Stock Company Creatinamide, verfahren zu ihrer herstellung und wirkstoff zur ausführung einer neuroprotektiven aktion
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
CA2806942C (en) * 2010-07-29 2019-06-25 Jocelyne Annat Compounds for the treatment/prevention of ocular inflammatory diseases
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
ATE64378T1 (de) * 1986-04-04 1991-06-15 Microbial Chem Res Found Spergualinaehnliche verbindungen und ihr herstellungsverfahren.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
CZ262293A3 (en) 1994-06-15
FR2698628B1 (fr) 1995-02-17
FI112211B (fi) 2003-11-14
FI935318A (fi) 1994-06-03
EP0600762B1 (fr) 1996-07-10
FR2698628A1 (fr) 1994-06-03
JPH06293728A (ja) 1994-10-21
ZA938821B (en) 1994-06-30
JP2945261B2 (ja) 1999-09-06
KR100187328B1 (ko) 1999-05-15
DE69303583T2 (de) 1996-11-21
HUT65782A (en) 1994-07-28
CA2110437C (en) 1999-04-13
DE69303583D1 (de) 1996-08-14
NZ250330A (en) 1995-06-27
KR940014435A (ko) 1994-07-18
NO934338L (no) 1994-06-03
US5476870A (en) 1995-12-19
HU9303406D0 (en) 1994-03-28
AU664124B2 (en) 1995-11-02
RU2114823C1 (ru) 1998-07-10
CZ284958B6 (cs) 1999-04-14
AU5188393A (en) 1994-06-16
FI935318A0 (fi) 1993-11-29
ATE140215T1 (de) 1996-07-15
GR3021269T3 (en) 1997-01-31
SK280286B6 (sk) 1999-11-08
NO934338D0 (no) 1993-11-30
CN1095709A (zh) 1994-11-30
TW311132B (ko) 1997-07-21
NO180483B (no) 1997-01-20
NO180483C (no) 1997-04-30
CA2110437A1 (en) 1994-06-03
EP0600762A1 (fr) 1994-06-08
CN1045431C (zh) 1999-10-06
SK135793A3 (en) 1994-06-08
ES2092263T3 (es) 1996-11-16
UA39920C2 (uk) 2001-07-16
DK0600762T3 (da) 1996-11-11
HU218908B (hu) 2000-12-28

Similar Documents

Publication Publication Date Title
HK1000467A1 (en) Analogues of the 15- deoxyspergualin process for their preparation and their use as immunosuppresants
IL101819A0 (en) Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
NZ218773A (en) 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions
RU93053038A (ru) Аналоги 15-деоксипергуалина, способ их получения и фармацевтическая композиция на их основе и промежуточные соединения синтеза
IL105669A0 (en) Dithiolanylglycine-containing hiv protease inhibitors of the hydroxyethylene isostere type,their preparation and pharmaceutical compositions containing them
UA41871C2 (uk) Похідні еритроміцину, спосіб їх одержання та фармацевтична композиція на їх основі
CA2143216A1 (en) 15-Deoxyspergualin Analogs, Their Method of Preparation and Their Use in Therapeutics
HU9202103D0 (en) Method for producing inosite-phosphate analogues and pharmaceutical preparatives containing these compounds
PL314794A1 (en) Crystalline polymorphous form of (s,s,s)-n-(1-[2-carbocy-3-(n2-mezilolysilamino)propyl]-1-cyclopentylocabonyl)thyrosine
IL103855A0 (en) 5,6-dihydro-dibenz(b,e)azepin-6,11-dione-11-oximes,their preparation and pharmaceutical compositions containing them
GR3017280T3 (en) Aminoalkylchromones, process for their preparation and compositions containing them.
PL286188A1 (en) Method of obtaining renine retarding aminooligohydroxy derivatives
ES2049186A1 (es) Procedimiento para la preparacion de nuevos derivados de benzofuranil-imidazol.
GR3025179T3 (en) Alpha-aryl-alpha-hydroxy-beta-imidazolinylpropionamides
GR3021200T3 (en) (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them.
IL84266A0 (en) 1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them
GR3024391T3 (en) Cyclised analogs of metabolites of fatty acids, process for their preparation and pharmaceutical compositions containing them.
IL103854A0 (en) 6-thiono-5,6-dihydro-dibenz(b,e)azepin-11-one-11-oximes,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20051117