GT200600420A - Sales novedosas de lisina de derivados de acido 4-((fenoxialquil)tio)-fenoxiacetico - Google Patents
Sales novedosas de lisina de derivados de acido 4-((fenoxialquil)tio)-fenoxiaceticoInfo
- Publication number
- GT200600420A GT200600420A GT200600420A GT200600420A GT200600420A GT 200600420 A GT200600420 A GT 200600420A GT 200600420 A GT200600420 A GT 200600420A GT 200600420 A GT200600420 A GT 200600420A GT 200600420 A GT200600420 A GT 200600420A
- Authority
- GT
- Guatemala
- Prior art keywords
- lisina
- salts
- phenoxialquil
- novedous
- phenoxyacetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/08—Acetic acid
- C07C53/10—Salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA SAL DE LISINA NOVEDOSA, COMPOSICIONES FARMACÉUTICAS QUE LAS CONTIENEN Y SU USO EN EL TRATAMIENTO DE TRASTORNOS Y CONDICIONES MODULADOS POR PPAR DELTA. LA PRESENTE INVENCIÓN SE REFIERE ADEMÁS A UN PROCESO NOVEDOSO PARA LA PREPARACIÓN DE DICHAS SALES DE LISINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71713705P | 2005-09-14 | 2005-09-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200600420A true GT200600420A (es) | 2007-05-08 |
Family
ID=37865545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200600420A GT200600420A (es) | 2005-09-14 | 2006-09-14 | Sales novedosas de lisina de derivados de acido 4-((fenoxialquil)tio)-fenoxiacetico |
Country Status (24)
Country | Link |
---|---|
US (2) | US7709682B2 (es) |
EP (1) | EP1937065B1 (es) |
JP (1) | JP5467770B2 (es) |
KR (5) | KR20180079468A (es) |
CN (1) | CN101304656B (es) |
AR (1) | AR058044A1 (es) |
AU (1) | AU2006291006B2 (es) |
BR (1) | BRPI0615835B8 (es) |
CA (1) | CA2622722C (es) |
DK (1) | DK1937065T3 (es) |
ES (1) | ES2535427T3 (es) |
GT (1) | GT200600420A (es) |
HK (1) | HK1122699A1 (es) |
HN (1) | HN2006032171A (es) |
HU (1) | HUE025185T2 (es) |
JO (1) | JO3006B1 (es) |
NZ (1) | NZ566504A (es) |
PE (1) | PE20070434A1 (es) |
PL (1) | PL1937065T3 (es) |
PT (1) | PT1937065E (es) |
SI (1) | SI1937065T1 (es) |
TW (1) | TWI414510B (es) |
UY (1) | UY29791A1 (es) |
WO (1) | WO2007033231A2 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA012241B1 (ru) | 2003-09-19 | 2009-08-28 | Янссен Фармацевтика, Н.В. | 4-((феноксиалкил)тио)феноксиуксусные кислоты и их аналоги |
ES2555031T3 (es) | 2003-09-19 | 2015-12-28 | Janssen Pharmaceutica N.V. | Ácidos y análogos 4-((fenoxialquilo)tio)-fenoxiacéticos |
MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
PE20080188A1 (es) * | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
ES2712052T3 (es) | 2008-10-17 | 2019-05-09 | Cymabay Therapeutics Inc | Métodos para reducir partículas de LDL pequeñas y densas |
AU2010278860B2 (en) | 2009-07-31 | 2016-05-26 | Thar Pharma, Llc | Crystallization method and bioavailability |
US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
HUE035744T2 (en) * | 2010-02-06 | 2018-05-28 | Gruenenthal Gmbh | Crystallization process and bioavailability |
AU2011296737A1 (en) | 2010-08-31 | 2013-04-11 | Snu R&Db Foundation | Use of the fetal reprogramming of a PPAR delta agonist |
US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
US20160279085A1 (en) * | 2013-11-20 | 2016-09-29 | Cymabay Therapeutics, Inc. | Treatment of Severe Hyperlipidemia |
US20150139987A1 (en) | 2013-11-20 | 2015-05-21 | Cymabay Therapeutics, Inc. | Treatment of homozygous familial hypercholesterolemia |
US10272058B2 (en) | 2014-03-20 | 2019-04-30 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
RS57970B1 (sr) * | 2014-03-20 | 2019-01-31 | Cymabay Therapeutics Inc | Tretman intrahepatičkih holestatskih oboljenja |
EA036704B1 (ru) * | 2014-04-11 | 2020-12-10 | Саймабэй Терапьютикс, Инк. | Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита |
CN106470675A (zh) * | 2014-06-26 | 2017-03-01 | 西玛贝医药公司 | 严重高甘油三酯血症的治疗 |
TW201808910A (zh) | 2016-05-16 | 2018-03-16 | 帝人製藥股份有限公司 | 喹啉衍生物之結晶 |
US10512622B2 (en) | 2017-07-14 | 2019-12-24 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
JP2020533339A (ja) | 2017-09-13 | 2020-11-19 | ノバルティス アーゲー | Fxrアゴニストを含む組合せ |
UA125600C2 (uk) | 2017-09-26 | 2022-04-27 | Сімабей Терапьютікс, Інк. | Лікування холестатичного свербежу |
WO2020102351A1 (en) * | 2018-11-16 | 2020-05-22 | Cymabay Therapeutics, Inc. | Treatment of obesity and its complications |
EA202191379A1 (ru) | 2018-11-16 | 2021-08-06 | Саймабэй Терапьютикс, Инк. | Комбинированное лечение nafld и nash |
US20230008367A1 (en) | 2019-09-26 | 2023-01-12 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
WO2021097034A1 (en) | 2019-11-14 | 2021-05-20 | Cymabay Therapeutics, Inc. | Seladelpar for use in the treatment of intestinal barrier dysfunction and associated diseases |
WO2021097027A1 (en) | 2019-11-14 | 2021-05-20 | Cymabay Therapeutics, Inc. | Seladelpar for use in the treatment of alcoholic liver disease |
WO2021098885A1 (zh) * | 2019-11-21 | 2021-05-27 | 杭州百诚医药科技股份有限公司 | α-氟代查耳酮类衍生物及其应用 |
WO2022165288A1 (en) | 2021-02-01 | 2022-08-04 | Cymabay Therapeutics, Inc. | Treatment of cholangiopathies with seladelpar |
WO2022189856A1 (en) | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
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EP0056172B1 (en) | 1981-01-09 | 1985-04-03 | FISONS plc | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them |
JPS58177934A (ja) | 1982-04-13 | 1983-10-18 | Takeda Chem Ind Ltd | ベンゾキノン誘導体 |
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GB0031107D0 (en) | 2000-12-20 | 2001-01-31 | Glaxo Group Ltd | Chemical compounds |
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ITRM20020014A1 (it) | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del |
JP4383177B2 (ja) | 2002-03-01 | 2009-12-16 | スミスクライン ビーチャム コーポレーション | hPPAR活性化剤 |
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ES2555031T3 (es) | 2003-09-19 | 2015-12-28 | Janssen Pharmaceutica N.V. | Ácidos y análogos 4-((fenoxialquilo)tio)-fenoxiacéticos |
BRPI0416106A (pt) | 2003-10-31 | 2007-01-02 | Janssen Pharmaceutica Nv | ácidos 4 -((fenoxialquil)tio)-fenoxiacéticos e análogos |
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MY145712A (en) | 2004-09-15 | 2012-03-30 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
PE20060664A1 (es) | 2004-09-15 | 2006-08-04 | Novartis Ag | Amidas biciclicas como inhibidores de cinasa |
JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
GB0618963D0 (en) | 2006-09-26 | 2006-11-08 | Ucl Business Plc | Formulations and composites with reactive fillers |
-
2006
- 2006-09-07 JO JOP/2006/0300A patent/JO3006B1/ar active
- 2006-09-13 CA CA2622722A patent/CA2622722C/en active Active
- 2006-09-13 BR BRPI0615835A patent/BRPI0615835B8/pt active IP Right Grant
- 2006-09-13 TW TW095133769A patent/TWI414510B/zh active
- 2006-09-13 KR KR1020187018792A patent/KR20180079468A/ko not_active Application Discontinuation
- 2006-09-13 DK DK06803483.4T patent/DK1937065T3/en active
- 2006-09-13 PL PL06803483T patent/PL1937065T3/pl unknown
- 2006-09-13 PE PE2006001117A patent/PE20070434A1/es active IP Right Grant
- 2006-09-13 US US11/531,464 patent/US7709682B2/en active Active
- 2006-09-13 WO PCT/US2006/035617 patent/WO2007033231A2/en active Application Filing
- 2006-09-13 NZ NZ566504A patent/NZ566504A/en unknown
- 2006-09-13 KR KR1020137022058A patent/KR20130100800A/ko not_active Application Discontinuation
- 2006-09-13 ES ES06803483.4T patent/ES2535427T3/es active Active
- 2006-09-13 AU AU2006291006A patent/AU2006291006B2/en active Active
- 2006-09-13 JP JP2008531264A patent/JP5467770B2/ja active Active
- 2006-09-13 KR KR1020157001219A patent/KR20150013952A/ko active Application Filing
- 2006-09-13 AR ARP060103994A patent/AR058044A1/es not_active Application Discontinuation
- 2006-09-13 CN CN2006800405764A patent/CN101304656B/zh active Active
- 2006-09-13 KR KR1020167016579A patent/KR20160079129A/ko active Application Filing
- 2006-09-13 KR KR1020087008237A patent/KR20080046695A/ko not_active Application Discontinuation
- 2006-09-13 SI SI200631916T patent/SI1937065T1/sl unknown
- 2006-09-13 EP EP06803483.4A patent/EP1937065B1/en active Active
- 2006-09-13 PT PT06803483T patent/PT1937065E/pt unknown
- 2006-09-13 HU HUE06803483A patent/HUE025185T2/en unknown
- 2006-09-14 UY UY29791A patent/UY29791A1/es not_active Application Discontinuation
- 2006-09-14 GT GT200600420A patent/GT200600420A/es unknown
- 2006-09-14 HN HN2006032171A patent/HN2006032171A/es unknown
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2008
- 2008-12-29 HK HK08114013.6A patent/HK1122699A1/xx unknown
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2010
- 2010-03-18 US US12/726,457 patent/US8669288B2/en active Active
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