GT199900059A - Compuestos azapoliciclicos condensados con arilo. - Google Patents

Compuestos azapoliciclicos condensados con arilo.

Info

Publication number
GT199900059A
GT199900059A GT199900059A GT199900059A GT199900059A GT 199900059 A GT199900059 A GT 199900059A GT 199900059 A GT199900059 A GT 199900059A GT 199900059 A GT199900059 A GT 199900059A GT 199900059 A GT199900059 A GT 199900059A
Authority
GT
Guatemala
Prior art keywords
aryl
azapolyclic
compounds
southern
compounds condensed
Prior art date
Application number
GT199900059A
Other languages
English (en)
Inventor
Jotham Wadsworth Coe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199900059A publication Critical patent/GT199900059A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

ESTA INVENCIÒN SE REFIERE A COMPUESTOS AZAPOLICÌCLICOS CONDENSADOS CON ARILO, COMO SE DEFINE POR LA FÒRMULA I. LOS COMPUESTOS DE FÒRMULA I SE UNEN A SITIOS RECEPTORES ESPECÌFICOS NICOTÌNICOS DE ACETILCOLINA PRESENTES EN LAS NEURONAS Y SON ÙTILES PARA MODULAR LA FUNCIÒN COLINÈRGICA, TALES COMPUESTOS SON ÙTILES EN EL TRATAMIENTO DE LA ENFERMEDAD INFLAMATORIA DEL INTESTINO, VASOCONTRICCIÒN, DEPRESIÒN, AUTISMO, OBESIDAD CEFALALGIAS, PSICOSIS, MAL ALZHEIMER.
GT199900059A 1998-04-29 1999-04-20 Compuestos azapoliciclicos condensados con arilo. GT199900059A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8355698P 1998-04-29 1998-04-29

Publications (1)

Publication Number Publication Date
GT199900059A true GT199900059A (es) 2000-10-11

Family

ID=22179102

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199900059A GT199900059A (es) 1998-04-29 1999-04-20 Compuestos azapoliciclicos condensados con arilo.

Country Status (42)

Country Link
US (3) US6462035B1 (es)
EP (1) EP1076650B1 (es)
JP (1) JP2002513007A (es)
KR (1) KR100420423B1 (es)
CN (1) CN1144787C (es)
AP (1) AP1154A (es)
AR (1) AR018596A1 (es)
AT (1) ATE258921T1 (es)
AU (1) AU749831B2 (es)
BG (1) BG64556B1 (es)
BR (1) BR9910058A (es)
CA (1) CA2330576A1 (es)
CO (1) CO5021124A1 (es)
DE (1) DE69914594T2 (es)
DK (1) DK1076650T3 (es)
DZ (1) DZ2778A1 (es)
EA (1) EA003669B1 (es)
ES (1) ES2213354T3 (es)
GT (1) GT199900059A (es)
HK (1) HK1036453A1 (es)
HR (1) HRP20000731A2 (es)
HU (1) HUP0103340A3 (es)
ID (1) ID26700A (es)
IL (1) IL138917A0 (es)
IS (1) IS5649A (es)
MA (1) MA26623A1 (es)
MY (1) MY133474A (es)
NO (1) NO317300B1 (es)
NZ (1) NZ507035A (es)
OA (1) OA11506A (es)
PA (1) PA8471301A1 (es)
PE (1) PE20000435A1 (es)
PL (1) PL344010A1 (es)
PT (1) PT1076650E (es)
SK (1) SK15952000A3 (es)
TN (1) TNSN99080A1 (es)
TR (1) TR200003122T2 (es)
UA (1) UA61991C2 (es)
UY (1) UY25636A1 (es)
WO (1) WO1999055680A1 (es)
YU (1) YU64400A (es)
ZA (1) ZA992971B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1044189T2 (sl) 1997-12-31 2015-05-29 Pfizer Products Inc. Z arilom kondenzirane azapoliciklične spojine
US6605610B1 (en) 1997-12-31 2003-08-12 Pfizer Inc Aryl fused azapolycyclic compounds
US20010036943A1 (en) * 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
DE60225433T2 (de) * 2001-04-20 2008-06-12 Pfizer Products Inc., Groton Verfahren zur herstellung von 1,3-substituierte indene und aryl-annellierte azapolycyclische verbindungen
HUP0401967A2 (hu) * 2001-10-31 2005-01-28 Pfizer Products Inc. Nikotinsav-acetilkolin-receptor-agonisták alkalmazása nyugtalan láb szindróma kezelésére alkalmas gyógyszerkészítmények előállítására
DE60228478D1 (de) 2001-11-30 2008-10-02 Pfizer Prod Inc Aryl-annellierte azapolyzyklische verbindungen
US20060089400A1 (en) * 2002-05-03 2006-04-27 The Vernalis Group Of Companies Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases
US20040224963A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
CA2533100A1 (en) * 2003-07-21 2005-01-27 Pfizer Products Inc. Aryl fused azapolycyclic compounds
WO2005007655A1 (en) 2003-07-21 2005-01-27 Pfizer Products Inc. Nicotine addiction reducing heteroaryl fused azapolycyclic compounds
US20050043407A1 (en) * 2003-08-22 2005-02-24 Pfizer Inc Pharmaceutical composition for the prevention and treatment of addiction in a mammal
WO2006061711A1 (en) * 2004-12-07 2006-06-15 Pfizer Products Inc. 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a] inden-7-one derivatives which bind to neuronal nicotinic acetylcholine specific receptor sites and are useful in modulating cholinergic function and in the treatment of addictive disorders
US20060210498A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives for skin
US20060210497A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives
DE102005061426A1 (de) * 2005-12-22 2007-07-05 Grünenthal GmbH Substituierte tricyclische Piperidon-Derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687937A (en) * 1970-06-23 1972-08-29 Us Of America The 1,5-methano-3-benzazocine derivatives
JPS4914473A (es) * 1972-06-09 1974-02-07
JPS4924968A (es) * 1972-07-01 1974-03-05

Also Published As

Publication number Publication date
AU2951699A (en) 1999-11-16
DZ2778A1 (fr) 2005-04-23
AR018596A1 (es) 2001-11-28
PA8471301A1 (es) 2000-09-29
EP1076650A1 (en) 2001-02-21
PT1076650E (pt) 2004-05-31
US7122534B2 (en) 2006-10-17
CN1298394A (zh) 2001-06-06
CA2330576A1 (en) 1999-11-04
NZ507035A (en) 2003-05-30
EA003669B1 (ru) 2003-08-28
NO317300B1 (no) 2004-10-04
US6706702B2 (en) 2004-03-16
US20030008890A1 (en) 2003-01-09
HUP0103340A3 (en) 2002-10-28
DE69914594T2 (de) 2004-12-09
ID26700A (id) 2001-02-01
IL138917A0 (en) 2001-11-25
OA11506A (en) 2004-05-14
ZA992971B (en) 2000-10-30
IS5649A (is) 2000-09-29
HUP0103340A2 (hu) 2002-02-28
PE20000435A1 (es) 2000-05-26
AP9901524A0 (en) 1999-06-30
TNSN99080A1 (fr) 2005-11-10
AU749831B2 (en) 2002-07-04
SK15952000A3 (sk) 2002-06-04
KR20010043143A (ko) 2001-05-25
TR200003122T2 (tr) 2001-03-21
US6462035B1 (en) 2002-10-08
NO20005397D0 (no) 2000-10-26
NO20005397L (no) 2000-10-26
BG64556B1 (bg) 2005-07-29
ES2213354T3 (es) 2004-08-16
BR9910058A (pt) 2000-12-26
EP1076650B1 (en) 2004-02-04
PL344010A1 (en) 2001-09-24
YU64400A (sh) 2003-01-31
MA26623A1 (fr) 2004-12-20
DE69914594D1 (de) 2004-03-11
CN1144787C (zh) 2004-04-07
UA61991C2 (en) 2003-12-15
BG104983A (en) 2001-09-28
US20040167149A1 (en) 2004-08-26
CO5021124A1 (es) 2001-03-27
JP2002513007A (ja) 2002-05-08
AP1154A (en) 2003-03-27
MY133474A (en) 2007-11-30
HK1036453A1 (en) 2002-01-04
KR100420423B1 (ko) 2004-03-04
WO1999055680A1 (en) 1999-11-04
HRP20000731A2 (en) 2001-06-30
UY25636A1 (es) 2000-02-23
ATE258921T1 (de) 2004-02-15
DK1076650T3 (da) 2004-05-24
EA200000996A1 (ru) 2001-06-25

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