NO317300B1 - Arylkondenserte azapolycykliske forbindelser - Google Patents

Arylkondenserte azapolycykliske forbindelser Download PDF

Info

Publication number
NO317300B1
NO317300B1 NO20005397A NO20005397A NO317300B1 NO 317300 B1 NO317300 B1 NO 317300B1 NO 20005397 A NO20005397 A NO 20005397A NO 20005397 A NO20005397 A NO 20005397A NO 317300 B1 NO317300 B1 NO 317300B1
Authority
NO
Norway
Prior art keywords
trideca
triene
aza
tricyclo
tetraene
Prior art date
Application number
NO20005397A
Other languages
English (en)
Norwegian (no)
Other versions
NO20005397D0 (no
NO20005397L (no
Inventor
Jotham Wadsworth Coe
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20005397D0 publication Critical patent/NO20005397D0/no
Publication of NO20005397L publication Critical patent/NO20005397L/no
Publication of NO317300B1 publication Critical patent/NO317300B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO20005397A 1998-04-29 2000-10-26 Arylkondenserte azapolycykliske forbindelser NO317300B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8355698P 1998-04-29 1998-04-29
PCT/IB1999/000617 WO1999055680A1 (en) 1998-04-29 1999-04-08 Aryl fused azapolycyclic compounds

Publications (3)

Publication Number Publication Date
NO20005397D0 NO20005397D0 (no) 2000-10-26
NO20005397L NO20005397L (no) 2000-10-26
NO317300B1 true NO317300B1 (no) 2004-10-04

Family

ID=22179102

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005397A NO317300B1 (no) 1998-04-29 2000-10-26 Arylkondenserte azapolycykliske forbindelser

Country Status (42)

Country Link
US (3) US6462035B1 (es)
EP (1) EP1076650B1 (es)
JP (1) JP2002513007A (es)
KR (1) KR100420423B1 (es)
CN (1) CN1144787C (es)
AP (1) AP1154A (es)
AR (1) AR018596A1 (es)
AT (1) ATE258921T1 (es)
AU (1) AU749831B2 (es)
BG (1) BG64556B1 (es)
BR (1) BR9910058A (es)
CA (1) CA2330576A1 (es)
CO (1) CO5021124A1 (es)
DE (1) DE69914594T2 (es)
DK (1) DK1076650T3 (es)
DZ (1) DZ2778A1 (es)
EA (1) EA003669B1 (es)
ES (1) ES2213354T3 (es)
GT (1) GT199900059A (es)
HK (1) HK1036453A1 (es)
HR (1) HRP20000731A2 (es)
HU (1) HUP0103340A3 (es)
ID (1) ID26700A (es)
IL (1) IL138917A0 (es)
IS (1) IS5649A (es)
MA (1) MA26623A1 (es)
MY (1) MY133474A (es)
NO (1) NO317300B1 (es)
NZ (1) NZ507035A (es)
OA (1) OA11506A (es)
PA (1) PA8471301A1 (es)
PE (1) PE20000435A1 (es)
PL (1) PL344010A1 (es)
PT (1) PT1076650E (es)
SK (1) SK15952000A3 (es)
TN (1) TNSN99080A1 (es)
TR (1) TR200003122T2 (es)
UA (1) UA61991C2 (es)
UY (1) UY25636A1 (es)
WO (1) WO1999055680A1 (es)
YU (1) YU64400A (es)
ZA (1) ZA992971B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605610B1 (en) * 1997-12-31 2003-08-12 Pfizer Inc Aryl fused azapolycyclic compounds
US6410550B1 (en) * 1997-12-31 2002-06-25 Pfizer Inc Aryl fused azapolycyclic compounds
US20010036943A1 (en) * 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
AU2002234836B2 (en) * 2001-04-20 2007-08-23 Pfizer Products Inc. Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds
PL370549A1 (en) * 2001-10-31 2005-05-30 Pfizer Products Inc. Nicotinic acetylcholine receptor agonists in the treatment of restless legs syndrome
ATE405574T1 (de) 2001-11-30 2008-09-15 Pfizer Prod Inc Aryl-annellierte azapolyzyklische verbindungen
US20060089400A1 (en) * 2002-05-03 2006-04-27 The Vernalis Group Of Companies Novel spiro ketone and carboxylic acid derivatives as specific inhibitors for (po3h2) ser/(po3h2)thr-pro-specific peptidyl-prolylcis/trans-isomerases
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
US20040224963A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal
BRPI0412712A (pt) 2003-07-21 2006-09-26 Pfizer Prod Inc compostos azapolicìclicos fundidos com heteroarila
CA2533100A1 (en) * 2003-07-21 2005-01-27 Pfizer Products Inc. Aryl fused azapolycyclic compounds
US20050043407A1 (en) * 2003-08-22 2005-02-24 Pfizer Inc Pharmaceutical composition for the prevention and treatment of addiction in a mammal
CA2591330A1 (en) * 2004-12-07 2006-06-15 Pfizer Products Inc. 1, 2, 3, 3a, 8, 8a-hexahydro-2, 7a-diada-cyclopenta [a] inden-7-one derivatives which bind to neuronal nicotinic acetylcholine specific receptor sites and are useful in modulatingcholinergic function and in the treatment of addictive disorders
US20060210498A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives for skin
US20060210497A1 (en) * 2005-03-18 2006-09-21 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Novel resorcinol derivatives
DE102005061426A1 (de) * 2005-12-22 2007-07-05 Grünenthal GmbH Substituierte tricyclische Piperidon-Derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687937A (en) * 1970-06-23 1972-08-29 Us Of America The 1,5-methano-3-benzazocine derivatives
JPS4914473A (es) * 1972-06-09 1974-02-07
JPS4924968A (es) * 1972-07-01 1974-03-05

Also Published As

Publication number Publication date
EA200000996A1 (ru) 2001-06-25
OA11506A (en) 2004-05-14
DK1076650T3 (da) 2004-05-24
KR100420423B1 (ko) 2004-03-04
AU2951699A (en) 1999-11-16
HRP20000731A2 (en) 2001-06-30
ES2213354T3 (es) 2004-08-16
EP1076650A1 (en) 2001-02-21
PE20000435A1 (es) 2000-05-26
AU749831B2 (en) 2002-07-04
US6462035B1 (en) 2002-10-08
ZA992971B (en) 2000-10-30
IL138917A0 (en) 2001-11-25
UY25636A1 (es) 2000-02-23
PA8471301A1 (es) 2000-09-29
YU64400A (sh) 2003-01-31
CO5021124A1 (es) 2001-03-27
NO20005397D0 (no) 2000-10-26
EP1076650B1 (en) 2004-02-04
BR9910058A (pt) 2000-12-26
DE69914594D1 (de) 2004-03-11
KR20010043143A (ko) 2001-05-25
AP9901524A0 (en) 1999-06-30
DZ2778A1 (fr) 2005-04-23
AR018596A1 (es) 2001-11-28
UA61991C2 (en) 2003-12-15
NO20005397L (no) 2000-10-26
HUP0103340A3 (en) 2002-10-28
TR200003122T2 (tr) 2001-03-21
AP1154A (en) 2003-03-27
US7122534B2 (en) 2006-10-17
HK1036453A1 (en) 2002-01-04
TNSN99080A1 (fr) 2005-11-10
JP2002513007A (ja) 2002-05-08
US20030008890A1 (en) 2003-01-09
CN1144787C (zh) 2004-04-07
DE69914594T2 (de) 2004-12-09
ID26700A (id) 2001-02-01
CN1298394A (zh) 2001-06-06
NZ507035A (en) 2003-05-30
SK15952000A3 (sk) 2002-06-04
GT199900059A (es) 2000-10-11
ATE258921T1 (de) 2004-02-15
US6706702B2 (en) 2004-03-16
HUP0103340A2 (hu) 2002-02-28
MY133474A (en) 2007-11-30
BG64556B1 (bg) 2005-07-29
BG104983A (en) 2001-09-28
EA003669B1 (ru) 2003-08-28
MA26623A1 (fr) 2004-12-20
IS5649A (is) 2000-09-29
CA2330576A1 (en) 1999-11-04
PT1076650E (pt) 2004-05-31
PL344010A1 (en) 2001-09-24
US20040167149A1 (en) 2004-08-26
WO1999055680A1 (en) 1999-11-04

Similar Documents

Publication Publication Date Title
US20030130261A1 (en) Aryl fused azapolycyclic compounds
NO317300B1 (no) Arylkondenserte azapolycykliske forbindelser
KR100408138B1 (ko) 아릴 융합된 아자폴리사이클릭 화합물
KR100551183B1 (ko) 1,3-치환 인덴 및 아릴-융합 아자폴리시클릭 화합물의제조 방법
EP0955301A2 (en) 7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylchloline receptors
AU2002234836A1 (en) Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds
Ohba et al. Intramolecular Diels–Alder reactions of oxazole–olefins: synthesis of the Rauwolfia alkaloids suaveoline and norsuaveoline
JP2008523045A (ja) ニューロンニコチン性アセチルコリン特異的受容体部位に結合し、コリン作動性機能の調節および習慣性障害の治療に有用である1,2,3,3a,8,8a−ヘキサヒドロ−2,7a−ジアダ−シクロペンタ[a]インデン−7−オン誘導体
HU222038B1 (hu) Eljárás norbenzomorfánszármazékok előállítására
Evans et al. Transannular reactions of dibenzo [a, d] cycloalkenes. 2. Synthesis of bridgehead substituted dibenzo [a, d] cycloalkenimines by a regiospecific transannular amine to olefin addition
JP3541952B2 (ja) 4−アリールイソインドール鎮痛薬
Pedrosa et al. Synthesis of enantiopure mono-and disubstituted tetrahydroisoquinolines by 6-exo radical cyclizations
JP2006528170A (ja) アリール縮合型アザ多環式化合物
Michne et al. Benzo [g] quinolines. I. Synthesis and pharmacological evaluation of cis-and trans-1-alkyl-5, 5-dimethyl-1, 2, 3, 4a, 5, 10, 10a-octahydrobenzo [g] quinolin-7-ol. A class of narcotic antagonists
MXPA00010540A (es) Compuestos azapoliciclicos condensados con arilo
CZ20003972A3 (cs) Aryl-arelované azapolycyklické sloučeniny
Nussbaumer et al. Ready access to 6-alkyl, 6-phenyl, 5, 6-dialkyl, and 5-alkyl-6-phenyl substituted 1, 2, 3, 4-tetrahydroisoquinolines
Cuthbertson New routes to indolizidine alkaloids: The total synthesis of (-)-grandisine B