GR930300134T1 - 1,3-bis- 3-(mono- or poly-hydroxy)acylamino-5-(mono- or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy- or hydroxyalkyl-propanes, their methods of preparation and x-ray contrast media containing them. - Google Patents

1,3-bis- 3-(mono- or poly-hydroxy)acylamino-5-(mono- or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy- or hydroxyalkyl-propanes, their methods of preparation and x-ray contrast media containing them.

Info

Publication number
GR930300134T1
GR930300134T1 GR930300134T GR930300134T GR930300134T1 GR 930300134 T1 GR930300134 T1 GR 930300134T1 GR 930300134 T GR930300134 T GR 930300134T GR 930300134 T GR930300134 T GR 930300134T GR 930300134 T1 GR930300134 T1 GR 930300134T1
Authority
GR
Greece
Prior art keywords
mono
hydroxy
hydroxyalkyl
poly
propanes
Prior art date
Application number
GR930300134T
Other languages
English (en)
Inventor
Fulvio Uggeri
Marino Brocchetta
Original Assignee
Dibra Spa
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dibra Spa, Bracco Spa filed Critical Dibra Spa
Publication of GR930300134T1 publication Critical patent/GR930300134T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR930300134T 1990-11-16 1994-02-28 1,3-bis- 3-(mono- or poly-hydroxy)acylamino-5-(mono- or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy- or hydroxyalkyl-propanes, their methods of preparation and x-ray contrast media containing them. GR930300134T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT02208890A IT1245853B (it) 1990-11-16 1990-11-16 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
PCT/EP1991/002151 WO1992008691A1 (en) 1990-11-16 1991-11-15 1,3-bis-[3-(mono- or poly-hydroxy)acylamino-5-(mono- or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes, their methods of preparation and x-ray contrast media containing them

Publications (1)

Publication Number Publication Date
GR930300134T1 true GR930300134T1 (en) 1994-02-28

Family

ID=11191331

Family Applications (1)

Application Number Title Priority Date Filing Date
GR930300134T GR930300134T1 (en) 1990-11-16 1994-02-28 1,3-bis- 3-(mono- or poly-hydroxy)acylamino-5-(mono- or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy- or hydroxyalkyl-propanes, their methods of preparation and x-ray contrast media containing them.

Country Status (19)

Country Link
EP (1) EP0557345B1 (el)
JP (1) JP2977613B2 (el)
KR (1) KR930702281A (el)
AT (1) ATE111441T1 (el)
AU (1) AU646119B2 (el)
CA (1) CA2096136A1 (el)
DE (2) DE69104059T2 (el)
DK (1) DK0557345T3 (el)
ES (1) ES2060415T3 (el)
GR (1) GR930300134T1 (el)
HU (1) HUT65652A (el)
IE (1) IE66460B1 (el)
IL (1) IL100054A (el)
IS (1) IS3781A7 (el)
IT (1) IT1245853B (el)
MX (1) MX9102103A (el)
NZ (1) NZ240566A (el)
WO (1) WO1992008691A1 (el)
ZA (1) ZA919065B (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717799B1 (fr) * 1994-03-22 1996-07-19 Guerbet Sa Composés polyiodes : procédé de préparation ; composition de diagnostic.
PT1829565E (pt) 2001-12-20 2010-04-26 Bone Support Ab Novo substituto mineral de osso
WO2006002875A1 (en) 2004-07-02 2006-01-12 Bracco Imaging Spa Contrast agents endowed with high relaxivity for use in magnetic resonance imaging (mri) which contain a chelating moiety with polyhydroxylated substituents
US7407647B2 (en) 2005-12-07 2008-08-05 Cordis Corporation Organic radiographic contrasting agents for medical devices
US20070134163A1 (en) 2005-12-13 2007-06-14 Zhao Jonathon Z Radiographic contrasting agents and radio-opaque polymeric materials for medical devices
US8067637B2 (en) * 2006-02-14 2011-11-29 Ge Healthcare As Contrast agents
KR20100033405A (ko) 2007-07-12 2010-03-29 지이 헬스케어 에이에스 조영제
JP2011500530A (ja) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011500532A (ja) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
WO2009047319A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
GB2453654A (en) * 2007-10-12 2009-04-15 Ge Healthcare As A compound for use in X-ray contrast examinations
ES2413160T3 (es) * 2007-10-12 2013-07-15 Ge Healthcare As Agentes de contraste
WO2009056555A1 (en) * 2007-10-30 2009-05-07 Ge Healthcare As Contrast agents
WO2009071605A1 (en) * 2007-12-05 2009-06-11 Ge Healthcare As Contrast agents
US20110158909A1 (en) * 2008-02-01 2011-06-30 Trustees Of Boston University Cationic Contrast Agents and Methods of Use Thereof
US20110021824A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Adsorptive purification method for iodixanol
US11065201B2 (en) 2014-11-21 2021-07-20 Technical University Of Denmark Gel formulations for local drug release
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
CN109475491B (zh) 2016-05-20 2022-06-24 丹麦技术大学 可触诊的标记物组合物
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
EP3982922A1 (en) 2019-06-12 2022-04-20 Technical University of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1491129A (en) * 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
CH626873A5 (el) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel

Also Published As

Publication number Publication date
EP0557345B1 (en) 1994-09-14
MX9102103A (es) 1992-06-01
IL100054A0 (en) 1992-08-18
JPH06504268A (ja) 1994-05-19
ES2060415T3 (es) 1994-11-16
DK0557345T3 (da) 1995-03-06
KR930702281A (ko) 1993-09-08
ZA919065B (en) 1992-08-26
DE557345T1 (de) 1994-07-28
IE913986A1 (en) 1992-05-20
DE69104059D1 (de) 1994-10-20
HUT65652A (en) 1994-07-28
DE69104059T2 (de) 1995-02-02
ATE111441T1 (de) 1994-09-15
IT9022088A1 (it) 1992-05-17
IT9022088A0 (it) 1990-11-16
HU9301375D0 (en) 1993-09-28
JP2977613B2 (ja) 1999-11-15
WO1992008691A1 (en) 1992-05-29
EP0557345A1 (en) 1993-09-01
AU646119B2 (en) 1994-02-10
AU8925391A (en) 1992-06-11
IS3781A7 (is) 1992-05-17
IL100054A (en) 1996-05-14
IT1245853B (it) 1994-10-25
IE66460B1 (en) 1995-12-27
CA2096136A1 (en) 1992-05-17
NZ240566A (en) 1994-02-25

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