ZA919065B - 1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them - Google Patents

1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them

Info

Publication number
ZA919065B
ZA919065B ZA919065A ZA919065A ZA919065B ZA 919065 B ZA919065 B ZA 919065B ZA 919065 A ZA919065 A ZA 919065A ZA 919065 A ZA919065 A ZA 919065A ZA 919065 B ZA919065 B ZA 919065B
Authority
ZA
South Africa
Prior art keywords
mono
hydroxy
hydroxyalkyl
poly
propanes
Prior art date
Application number
ZA919065A
Inventor
Fulvio Uggeri
Uggeri Fulvio
Marino Brochetta
Brochetta Marino
Original Assignee
Bracco Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Ind Chimica Spa filed Critical Bracco Ind Chimica Spa
Publication of ZA919065B publication Critical patent/ZA919065B/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Symmetrical or asymmetrical 1,3-bis-[3-(mono- or poly-hydroxy)acylamino-5-(mono- or polyhydroxyalkyl)-aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes, useful to constitute the opacifying component of X-ray contrast media, are described.
ZA919065A 1990-11-16 1991-11-15 1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them ZA919065B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02208890A IT1245853B (en) 1990-11-16 1990-11-16 1,3-BIS (3- (MONO OR POLYHYDROXY) ACYLAMINE-5- (MONO OR POLYHYDROXY-ALCHYL) AMINOCARBONYL-2,4,6-TRIIODE-BENZOYL-AMINO) -HYDROXY- OR HYDROXY-ALCHYL-PROPANE, THEIR METHOD OF PREPARATION AND ROENTGENOGRAPHIC CONTRAST MEANS THAT CONTAIN THEM

Publications (1)

Publication Number Publication Date
ZA919065B true ZA919065B (en) 1992-08-26

Family

ID=11191331

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919065A ZA919065B (en) 1990-11-16 1991-11-15 1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxyalkyl)aminocarbonyl-2,4,6-triiodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them

Country Status (19)

Country Link
EP (1) EP0557345B1 (en)
JP (1) JP2977613B2 (en)
KR (1) KR930702281A (en)
AT (1) ATE111441T1 (en)
AU (1) AU646119B2 (en)
CA (1) CA2096136A1 (en)
DE (2) DE69104059T2 (en)
DK (1) DK0557345T3 (en)
ES (1) ES2060415T3 (en)
GR (1) GR930300134T1 (en)
HU (1) HUT65652A (en)
IE (1) IE66460B1 (en)
IL (1) IL100054A (en)
IS (1) IS3781A7 (en)
IT (1) IT1245853B (en)
MX (1) MX9102103A (en)
NZ (1) NZ240566A (en)
WO (1) WO1992008691A1 (en)
ZA (1) ZA919065B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717799B1 (en) * 1994-03-22 1996-07-19 Guerbet Sa Polyiodes compounds: preparation process; diagnostic composition.
PT1829565E (en) 2001-12-20 2010-04-26 Bone Support Ab A new bone mineral substitute
WO2006002875A1 (en) 2004-07-02 2006-01-12 Bracco Imaging Spa Contrast agents endowed with high relaxivity for use in magnetic resonance imaging (mri) which contain a chelating moiety with polyhydroxylated substituents
US7407647B2 (en) 2005-12-07 2008-08-05 Cordis Corporation Organic radiographic contrasting agents for medical devices
US20070134163A1 (en) 2005-12-13 2007-06-14 Zhao Jonathon Z Radiographic contrasting agents and radio-opaque polymeric materials for medical devices
US8067637B2 (en) * 2006-02-14 2011-11-29 Ge Healthcare As Contrast agents
KR20100033405A (en) 2007-07-12 2010-03-29 지이 헬스케어 에이에스 Contrast agents
JP2011500530A (en) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
JP2011500532A (en) * 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
WO2009047319A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
GB2453654A (en) * 2007-10-12 2009-04-15 Ge Healthcare As A compound for use in X-ray contrast examinations
ES2413160T3 (en) * 2007-10-12 2013-07-15 Ge Healthcare As Contrast agents
WO2009056555A1 (en) * 2007-10-30 2009-05-07 Ge Healthcare As Contrast agents
WO2009071605A1 (en) * 2007-12-05 2009-06-11 Ge Healthcare As Contrast agents
US20110158909A1 (en) * 2008-02-01 2011-06-30 Trustees Of Boston University Cationic Contrast Agents and Methods of Use Thereof
US20110021824A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Adsorptive purification method for iodixanol
US11065201B2 (en) 2014-11-21 2021-07-20 Technical University Of Denmark Gel formulations for local drug release
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
CN109475491B (en) 2016-05-20 2022-06-24 丹麦技术大学 Palpable marker compositions
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
EP3982922A1 (en) 2019-06-12 2022-04-20 Technical University of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1491129A (en) * 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
CH626873A5 (en) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
DE3731542A1 (en) * 1987-09-17 1989-03-30 Schering Ag NEW DICARBONIC ACID-BIS (3,5-DICARBAMOYL-2,4,6-TRIIOD-ANILIDE), METHOD FOR THE PRODUCTION THEREOF AND THESE CONTAINING X-RAY AGENTS

Also Published As

Publication number Publication date
EP0557345B1 (en) 1994-09-14
MX9102103A (en) 1992-06-01
IL100054A0 (en) 1992-08-18
JPH06504268A (en) 1994-05-19
ES2060415T3 (en) 1994-11-16
DK0557345T3 (en) 1995-03-06
KR930702281A (en) 1993-09-08
DE557345T1 (en) 1994-07-28
IE913986A1 (en) 1992-05-20
DE69104059D1 (en) 1994-10-20
HUT65652A (en) 1994-07-28
DE69104059T2 (en) 1995-02-02
ATE111441T1 (en) 1994-09-15
IT9022088A1 (en) 1992-05-17
IT9022088A0 (en) 1990-11-16
HU9301375D0 (en) 1993-09-28
JP2977613B2 (en) 1999-11-15
GR930300134T1 (en) 1994-02-28
WO1992008691A1 (en) 1992-05-29
EP0557345A1 (en) 1993-09-01
AU646119B2 (en) 1994-02-10
AU8925391A (en) 1992-06-11
IS3781A7 (en) 1992-05-17
IL100054A (en) 1996-05-14
IT1245853B (en) 1994-10-25
IE66460B1 (en) 1995-12-27
CA2096136A1 (en) 1992-05-17
NZ240566A (en) 1994-02-25

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