IL100054A0 - 1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxy-alkyl)aminocarbonyl-2,4,6-triodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them - Google Patents

1,3-bis-(3-(mono-or poly-hydroxy)acylamino-5-(mono-or poly-hydroxy-alkyl)aminocarbonyl-2,4,6-triodo-benzoyl-amino)-hydroxy-or hydroxyalkyl-propanes,their methods of preparation and x-ray contrast media containing them

Info

Publication number
IL100054A0
IL100054A0 IL100054A IL10005491A IL100054A0 IL 100054 A0 IL100054 A0 IL 100054A0 IL 100054 A IL100054 A IL 100054A IL 10005491 A IL10005491 A IL 10005491A IL 100054 A0 IL100054 A0 IL 100054A0
Authority
IL
Israel
Prior art keywords
hydroxy
mono
poly
propanes
aminocarbonyl
Prior art date
Application number
IL100054A
Other versions
IL100054A (en
Original Assignee
Bracco Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Ind Chimica Spa filed Critical Bracco Ind Chimica Spa
Publication of IL100054A0 publication Critical patent/IL100054A0/en
Publication of IL100054A publication Critical patent/IL100054A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Symmetrical or asymmetrical 1,3-bis-[3-(mono- or poly-hydroxy)acylamino-5-(mono- or polyhydroxyalkyl)-aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes, useful to constitute the opacifying component of X-ray contrast media, are described.
IL10005491A 1990-11-16 1991-11-14 1,3-bis-[3-(mono- or poly-hydroxy) acylamino-5-(mono- or poly-hydroxyalkyl) aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes their methods of preparation and x-ray contrast media containing them IL100054A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02208890A IT1245853B (en) 1990-11-16 1990-11-16 1,3-BIS (3- (MONO OR POLYHYDROXY) ACYLAMINE-5- (MONO OR POLYHYDROXY-ALCHYL) AMINOCARBONYL-2,4,6-TRIIODE-BENZOYL-AMINO) -HYDROXY- OR HYDROXY-ALCHYL-PROPANE, THEIR METHOD OF PREPARATION AND ROENTGENOGRAPHIC CONTRAST MEANS THAT CONTAIN THEM

Publications (2)

Publication Number Publication Date
IL100054A0 true IL100054A0 (en) 1992-08-18
IL100054A IL100054A (en) 1996-05-14

Family

ID=11191331

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10005491A IL100054A (en) 1990-11-16 1991-11-14 1,3-bis-[3-(mono- or poly-hydroxy) acylamino-5-(mono- or poly-hydroxyalkyl) aminocarbonyl-2,4,6-triiodo-benzoyl-amino]-hydroxy- or hydroxyalkyl-propanes their methods of preparation and x-ray contrast media containing them

Country Status (19)

Country Link
EP (1) EP0557345B1 (en)
JP (1) JP2977613B2 (en)
KR (1) KR930702281A (en)
AT (1) ATE111441T1 (en)
AU (1) AU646119B2 (en)
CA (1) CA2096136A1 (en)
DE (2) DE69104059T2 (en)
DK (1) DK0557345T3 (en)
ES (1) ES2060415T3 (en)
GR (1) GR930300134T1 (en)
HU (1) HUT65652A (en)
IE (1) IE66460B1 (en)
IL (1) IL100054A (en)
IS (1) IS3781A7 (en)
IT (1) IT1245853B (en)
MX (1) MX9102103A (en)
NZ (1) NZ240566A (en)
WO (1) WO1992008691A1 (en)
ZA (1) ZA919065B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717799B1 (en) * 1994-03-22 1996-07-19 Guerbet Sa Polyiodes compounds: preparation process; diagnostic composition.
DE60235423D1 (en) 2001-12-20 2010-04-01 Bone Support Ab New bone mineral replacement
CN101090739B (en) 2004-07-02 2012-10-10 伯拉考成像股份公司 1,4-bis(carboxymethyl)-6-[bis(carboxymethyl)amino]-6-methyl-perhydro-1,4-diazepine (aazta) derivatives as ligands in high relaxivity contrast agents for use in magnetic resonance imaging (mri)
US7407647B2 (en) 2005-12-07 2008-08-05 Cordis Corporation Organic radiographic contrasting agents for medical devices
US20070134163A1 (en) * 2005-12-13 2007-06-14 Zhao Jonathon Z Radiographic contrasting agents and radio-opaque polymeric materials for medical devices
US8067637B2 (en) * 2006-02-14 2011-11-29 Ge Healthcare As Contrast agents
BRPI0814811A2 (en) 2007-07-12 2015-02-03 Ge Healthcare As COMPOUND, AGENT, METHOD, AND DIAGNOSTIC COMPOSITION, USE OF A COMPOUND, AND IMAGE FORMATION METHOD
WO2009047319A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
WO2009047318A1 (en) 2007-10-12 2009-04-16 Ge Healthcare As Contrast agents
GB2453654A (en) * 2007-10-12 2009-04-15 Ge Healthcare As A compound for use in X-ray contrast examinations
CN101820924A (en) 2007-10-12 2010-09-01 通用电气医疗集团股份有限公司 Contrast agents
EP2200971B1 (en) * 2007-10-12 2013-04-24 GE Healthcare AS Contrast agents
EP2203190A1 (en) * 2007-10-30 2010-07-07 GE Healthcare AS Contrast agents
CN101888858A (en) * 2007-12-05 2010-11-17 通用电气医疗集团股份有限公司 Contrast agent
EP2247314A4 (en) * 2008-02-01 2013-11-27 Univ Boston Cationic contrast agents and methods of use thereof
US20110021824A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Adsorptive purification method for iodixanol
CN107249570B (en) 2014-11-21 2022-08-09 丹麦技术大学 Gel formulations for topical drug delivery
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
EP3458029A1 (en) 2016-05-20 2019-03-27 Technical University of Denmark Palpable marker composition
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2020249801A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1491129A (en) * 1975-06-04 1977-11-09 Guerbet Sa Iodo-benzene derivatives and an x-ray contrast medium containing them
CH626873A5 (en) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
DE3731542A1 (en) * 1987-09-17 1989-03-30 Schering Ag NEW DICARBONIC ACID-BIS (3,5-DICARBAMOYL-2,4,6-TRIIOD-ANILIDE), METHOD FOR THE PRODUCTION THEREOF AND THESE CONTAINING X-RAY AGENTS

Also Published As

Publication number Publication date
WO1992008691A1 (en) 1992-05-29
DE69104059D1 (en) 1994-10-20
ZA919065B (en) 1992-08-26
IT1245853B (en) 1994-10-25
NZ240566A (en) 1994-02-25
JP2977613B2 (en) 1999-11-15
IE66460B1 (en) 1995-12-27
KR930702281A (en) 1993-09-08
AU646119B2 (en) 1994-02-10
GR930300134T1 (en) 1994-02-28
MX9102103A (en) 1992-06-01
ATE111441T1 (en) 1994-09-15
DK0557345T3 (en) 1995-03-06
ES2060415T3 (en) 1994-11-16
IE913986A1 (en) 1992-05-20
IT9022088A0 (en) 1990-11-16
IL100054A (en) 1996-05-14
EP0557345A1 (en) 1993-09-01
IS3781A7 (en) 1992-05-17
DE69104059T2 (en) 1995-02-02
HU9301375D0 (en) 1993-09-28
DE557345T1 (en) 1994-07-28
EP0557345B1 (en) 1994-09-14
HUT65652A (en) 1994-07-28
AU8925391A (en) 1992-06-11
CA2096136A1 (en) 1992-05-17
IT9022088A1 (en) 1992-05-17
JPH06504268A (en) 1994-05-19

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