GR852817B - - Google Patents

Info

Publication number
GR852817B
GR852817B GR852817A GR850102817A GR852817B GR 852817 B GR852817 B GR 852817B GR 852817 A GR852817 A GR 852817A GR 850102817 A GR850102817 A GR 850102817A GR 852817 B GR852817 B GR 852817B
Authority
GR
Greece
Prior art keywords
och3
ch2ch3
hal
compounds
och2ch3
Prior art date
Application number
GR852817A
Other languages
English (en)
Inventor
Arto Johannes Karjalainen
Raimo Eiwari Virtanen
Arja Leena Karjalainen
Kauko Oiva Antero Kurkela
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of GR852817B publication Critical patent/GR852817B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
GR852817A 1984-11-23 1985-11-21 GR852817B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08429578A GB2167408B (en) 1984-11-23 1984-11-23 Substituted imidazole derivatives and their preparation and use

Publications (1)

Publication Number Publication Date
GR852817B true GR852817B (el) 1986-03-21

Family

ID=10570140

Family Applications (1)

Application Number Title Priority Date Filing Date
GR852817A GR852817B (el) 1984-11-23 1985-11-21

Country Status (26)

Country Link
US (1) US4689339A (el)
EP (2) EP0183492B1 (el)
JP (1) JPH064597B2 (el)
KR (1) KR930004673B1 (el)
AT (2) ATE85050T1 (el)
AU (2) AU586839B2 (el)
BG (1) BG60762B2 (el)
CA (1) CA1268770C (el)
DD (1) DD258230A1 (el)
DE (2) DE3587045T2 (el)
DK (2) DK164903C (el)
ES (2) ES8704462A1 (el)
FI (1) FI80264C (el)
GB (1) GB2167408B (el)
GR (1) GR852817B (el)
HK (1) HK3592A (el)
HU (1) HU195189B (el)
IE (1) IE58165B1 (el)
IL (1) IL77111A (el)
NO (1) NO166585C (el)
NZ (1) NZ214258A (el)
PH (1) PH22016A (el)
PT (1) PT81542B (el)
SG (1) SG106891G (el)
SU (1) SU1424736A3 (el)
ZA (1) ZA858942B (el)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4891431A (en) * 1986-01-28 1990-01-02 Mitsui Petrochemical Industries, Ltd. Process for preparing 2-unsubstituted imidazoles
FI81092C (fi) * 1986-05-15 1990-09-10 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.
FI862039A0 (fi) * 1986-05-15 1986-05-15 Farmos Oy Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
JP2576493B2 (ja) * 1987-03-20 1997-01-29 アイシン精機株式会社 原稿読取り装置に用いられる原稿トレ−
FR2621327B1 (fr) * 1987-10-06 1990-01-05 Commissariat Energie Atomique Procede de production et d'extraction de polysaccharides a partir d'une culture de porphyridium cruentum et dispositif pour la mise en oeuvre du procede
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
GB8903437D0 (en) * 1989-02-15 1989-04-05 Erba Carlo Spa Imidazolyl derivatives of 3,4-dihydro-2h-1-benzothiopyran
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
GB2256135B (en) 1991-05-31 1995-01-18 Orion Yhtymae Oy Transdermal administration of 4-substituted imidazoles
US5541211A (en) * 1991-06-18 1996-07-30 Orion-Yhtyma Oy Administration of atipamezole to elicit a yohimbine-like alpha-adrenoreceptor antagonistic noradrenergic transmission
SK282098B6 (sk) * 1991-11-05 2001-11-06 Smithkline Beecham Corporation Indánové deriváty, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9127430D0 (en) * 1991-12-27 1992-02-19 Scras Benzofuranylimidazole derivatives
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
GB9425211D0 (en) * 1994-12-14 1995-02-15 Ucb Sa Substituted 1H-imidazoles
FR2733983B1 (fr) * 1995-05-10 1997-08-01 Pf Medicament Procede de preparation d'un derive d'acide benzofurane carboxylque optiquement pur et son utilisation pour preparer l'efaroxan
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
EP0986530A1 (en) * 1997-06-05 2000-03-22 Venantius Limited Indane compounds and their pharmaceutical use
WO1999051593A1 (en) * 1998-04-02 1999-10-14 Ortho-Mcneil Pharmaceutical, Inc. 4-thionaphthyl-1h-imidazoles with alpha-2-adrenergic activity
FR2784989B1 (fr) * 1998-09-10 2002-09-27 Fabre Pierre Sante Derive d'ester d'acide 2-ethyl-2,3-dihydrobenzofurane- carboxylique, procede de preparation et utilisation pour la preparation de derives de l'efaroxan
AU3033100A (en) * 1999-01-18 2000-08-01 Boehringer Ingelheim International Gmbh Substituted imidazoles, their preparation and use
US6388090B2 (en) * 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
US6593324B2 (en) 2000-03-01 2003-07-15 Orion Corporation Dervatives of quinoline as alpha-2 antagonists
CZ20023674A3 (cs) 2000-05-08 2003-09-17 Orion Corporation Nové polycyklické indanylimidazolové sloučeniny s alfa2 adrenergní aktivitou
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US6543389B2 (en) 2001-06-26 2003-04-08 Pfizer Inc. Insecticidal pet collar
PL372657A1 (en) 2002-04-03 2005-07-25 Orion Corporation Polycyclic compounds as potent alpha2-adrenoceptor antagonists
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
FI116292B (fi) 2003-01-08 2005-10-31 Juvantia Pharma Ltd Oy Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita
WO2005041950A1 (en) * 2003-11-04 2005-05-12 Akzo Nobel N.V. Ectoparasiticidal formulations of spinosyns and azole pesticides
FI20050657A0 (fi) * 2005-06-17 2005-06-17 Orion Corp Atipametsolin kiteytysmenetelmä
JP5584415B2 (ja) 2005-10-12 2014-09-03 ユニメッド・ファーマシューティカルズ・エルエルシー 改良したテストステロンゲル製剤及び使用の方法
US7592461B2 (en) * 2005-12-21 2009-09-22 Bristol-Myers Squibb Company Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US20100179205A1 (en) * 2006-08-08 2010-07-15 Intervet International B.V. Composition for Enhanced Antiparasitic Activity
TWI457122B (zh) 2007-07-20 2014-10-21 Orion Corp 作為用於治療周邊和中央神經系統疾病之alpha2C拮抗劑的2,3－二氫苯並[1,4]戴奧辛－2－基甲基衍生物
CL2008003553A1 (es) * 2007-12-05 2009-11-27 Grindeks Jsc Proceso para preparar atipamezol o clorhidrato de 5-(2-etil-2,3-dihidro-1h-inden-2-il)-1h-imidazol: y loa compuestos intermediarios considerados en el proceso
RU2687279C2 (ru) 2013-11-05 2019-05-13 3М Инновейтив Пропертиз Компани Инъекционные композиции на основе кунжутного масла
AR104882A1 (es) 2015-06-05 2017-08-23 Orion Corp DERIVADOS DE 2-(1-HETEROARILPIPERAZIN-4-IL)METIL-1,4-BENZODIOXANO COMO ANTAGONISTAS DE a2C
US20200383953A1 (en) * 2015-11-05 2020-12-10 University Of Louisville Research Foundation, Inc. Local and regional anesthesia and analgesia
KR20190020343A (ko) 2016-06-29 2019-02-28 오리온 코포레이션 벤조디옥산 유도체 및 이의 약제학적 용도
AU2019411230A1 (en) 2018-12-21 2021-06-10 Société des Produits Nestlé S.A. Nutritional composition for inducing a feeling of satiety, a better sleep and/or limiting nocturnal awaking in infants or young children
CN111978254A (zh) * 2019-05-22 2020-11-24 南京康德祥医药科技有限公司 一种阿替美唑盐酸盐的制备工艺
CN111925330A (zh) * 2020-09-07 2020-11-13 上海阿达玛斯试剂有限公司 一种阿替美唑的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2933962A1 (de) * 1979-08-22 1981-03-26 Hoechst Ag, 65929 Frankfurt Verfahren zur herstellung von 4,5-dichlor-imidazolen.
US4342775A (en) * 1980-03-04 1982-08-03 Farmitalia Carlo Erba S.P.A. 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran
US4302469A (en) * 1980-09-10 1981-11-24 Syntex (U.S.A.) Inc. 2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
ZW13782A1 (en) * 1981-07-28 1982-10-06 Reckitt & Colmann Prod Ltd Imidazoline derivatives
ES523609A0 (es) * 1982-07-05 1985-03-01 Erba Farmitalia Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.
FR2539415B1 (fr) * 1983-01-14 1985-09-13 Adir Derives de la d-2 imidazoline, leur preparation et leur application en therapeutique
FR2542738A1 (fr) * 1983-03-18 1984-09-21 Synthelabo Indanyl-2 d2-imidazoline, procede pour la preparer, et compositions pharmaceutiques qui la contiennent

Also Published As

Publication number Publication date
NZ214258A (en) 1989-02-24
NO854671L (no) 1986-05-26
PH22016A (en) 1988-05-13
ES8704462A1 (es) 1987-04-01
FI854335A0 (fi) 1985-11-05
BG60762B2 (bg) 1996-02-29
IE852929L (en) 1986-05-23
DK540485D0 (da) 1985-11-22
GB2167408B (en) 1988-05-25
EP0310745B1 (en) 1993-01-27
JPS61143366A (ja) 1986-07-01
ATE85050T1 (de) 1993-02-15
IL77111A (en) 1989-09-28
KR860004028A (ko) 1986-06-16
CA1266669A1 (en) 1990-03-13
HU195189B (en) 1988-04-28
IL77111A0 (en) 1986-04-29
AU3332989A (en) 1989-08-10
DK540485A (da) 1986-05-24
HK3592A (en) 1992-01-17
KR930004673B1 (ko) 1993-06-03
EP0310745A2 (en) 1989-04-12
SG106891G (en) 1992-02-14
GB2167408A (en) 1986-05-29
AU5008385A (en) 1986-05-29
CA1268770C (en) 1990-05-08
IE58165B1 (en) 1993-07-28
FI80264C (fi) 1990-05-10
SU1424736A3 (ru) 1988-09-15
EP0183492B1 (en) 1989-11-15
DK58292A (da) 1992-05-04
FI80264B (fi) 1990-01-31
ATE47997T1 (de) 1989-12-15
HUT38913A (en) 1986-07-28
NO166585B (no) 1991-05-06
AU586839B2 (en) 1989-07-27
ES549178A0 (es) 1987-04-01
FI854335A (fi) 1986-05-24
DK58292D0 (da) 1992-05-04
DE3587045T2 (de) 1993-06-03
ZA858942B (en) 1986-08-27
NO166585C (no) 1991-08-21
PT81542A (en) 1985-12-01
ES557268A0 (es) 1987-12-16
DD258230A1 (de) 1988-07-13
EP0183492A1 (en) 1986-06-04
DK164903C (da) 1993-01-25
PT81542B (pt) 1988-03-03
GB8429578D0 (en) 1985-01-03
US4689339A (en) 1987-08-25
ES8801248A1 (es) 1987-12-16
DE3574252D1 (en) 1989-12-21
DK164903B (da) 1992-09-07
DE3587045D1 (de) 1993-03-11
EP0310745A3 (en) 1989-10-11
JPH064597B2 (ja) 1994-01-19

Similar Documents

Publication Publication Date Title
GR852817B (el)
JO1351B1 (en) Chemical compounds
FI871655A (fi) Foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
IE820556L (en) Benzofurans
PH24176A (en) New bicyclic compounds,process for preparation thereof and pharmaceutical composition comprising the same
NZ213222A (en) 2-(3,5-dialkyl-4-hydroxyphenyl)-indole derivatives and pharmaceutical compositions
ES8500953A1 (es) Procedimiento para preparar derivados de tieno-tiazol
DE3160719D1 (en) Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them
ZA838139B (en) Semicarbazides,process for preparing these,and pharmaceutical compositions thereof