GR3027634T3 - Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them. - Google Patents
Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them.Info
- Publication number
- GR3027634T3 GR3027634T3 GR980401812T GR980401812T GR3027634T3 GR 3027634 T3 GR3027634 T3 GR 3027634T3 GR 980401812 T GR980401812 T GR 980401812T GR 980401812 T GR980401812 T GR 980401812T GR 3027634 T3 GR3027634 T3 GR 3027634T3
- Authority
- GR
- Greece
- Prior art keywords
- pct
- gallium
- obtention
- complexes
- iii
- Prior art date
Links
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052733 gallium Inorganic materials 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002346 iodo group Chemical group I* 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- CYFLXLSBHQBMFT-UHFFFAOYSA-N sulfamoxole Chemical group O1C(C)=C(C)N=C1NS(=O)(=O)C1=CC=C(N)C=C1 CYFLXLSBHQBMFT-UHFFFAOYSA-N 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402093 | 1991-07-25 | ||
| PCT/EP1992/001687 WO1993002087A1 (en) | 1991-07-25 | 1992-07-23 | Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3027634T3 true GR3027634T3 (en) | 1998-11-30 |
Family
ID=8208600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR980401812T GR3027634T3 (en) | 1991-07-25 | 1998-08-12 | Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5525598A (el) |
| EP (1) | EP0599881B1 (el) |
| JP (1) | JP3480498B2 (el) |
| AT (1) | ATE166056T1 (el) |
| AU (1) | AU2360092A (el) |
| CA (1) | CA2114136C (el) |
| DE (1) | DE69225484T2 (el) |
| ES (1) | ES2120450T3 (el) |
| GR (1) | GR3027634T3 (el) |
| WO (1) | WO1993002087A1 (el) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852146A (en) * | 1996-06-27 | 1998-12-22 | Union Carbide Chemicals & Plastics Technology Corporation | Catalyst for the production of olefin polymers |
| US6203822B1 (en) * | 1996-09-03 | 2001-03-20 | University Of Iowa Research Foundation | Gallium-containing compounds for the treatment of infections caused by intracellular pathogens and pathogens causing chronic pulmonary infection |
| DE60032915T2 (de) * | 1999-10-04 | 2007-10-25 | Bernstein, Lawrence Richard, Dr., Menlo Park | Gallium komplexe von 3-hydroxy-4-pyronen zur behandlung von durch intrazelluläre prokaryoten, dns- und retro-viren verursachten infektionen |
| US20020160055A1 (en) * | 2000-09-18 | 2002-10-31 | Jack Stapleton | Methods for treating human immunodeficiency virus infections with gallium compositions |
| DE10113185A1 (de) * | 2001-03-19 | 2002-10-24 | Faustus Forschungs Cie | Zusammensetzung, enthaltend einen Gallium(III)-Komplex und einen therapeutisch wirksamen Platin-Komplex |
| DE10116527C2 (de) * | 2001-04-03 | 2003-05-15 | Faustus Forschungs Cie | Tumorhemmende Galliumverbindungen, deren Verwendung als Arzneimittel sowie ein Arzneimittel, diese enthaltend |
| WO2005058331A1 (en) * | 2003-12-17 | 2005-06-30 | Titan Pharmaceuticals, Inc. | Use of gallium to treat inflammatory arthritis |
| ES2535311T3 (es) | 2004-12-29 | 2015-05-08 | Emisphere Technologies, Inc. | Formulaciones farmacéuticas de sales de galio |
| AT501262B8 (de) * | 2005-01-24 | 2007-02-15 | Faustus Forschung Translationa | Verwendung von gallium(iii)-komplexen zur behandlung von tumoren des urothelialtraktes |
| AT501819B1 (de) * | 2005-04-18 | 2007-01-15 | Faustus Forschung Translationa | Verwendung von gallium(iii)-komplexen zur behandlung von tumorerkrankungen der leber |
| EP1993567A4 (en) * | 2005-10-27 | 2011-01-26 | Lawrence Richard Bernstein | PER OS ADMINISTRABLE GALLIUM PREPARATIONS AND METHODS OF USE |
| CA2626029A1 (en) * | 2005-11-04 | 2007-05-18 | Genta Incorporated | Pharmaceutical gallium compositions and methods |
| EP1978976A2 (en) * | 2006-01-30 | 2008-10-15 | Titan Pharmaceuticals, Inc. | Use of gallium to treat biofilm-associated infectons |
| AT503317B1 (de) * | 2006-02-13 | 2007-09-15 | Faustus Forschung Translationa | Verwendung von gallium(iii)-komplexen zur herstellung eines medikaments zur behandlung von melanomen |
| CA2656019C (en) * | 2006-06-28 | 2016-09-13 | Emisphere Technologies, Inc. | Gallium nitrate formulations |
| US8168214B2 (en) * | 2006-11-09 | 2012-05-01 | Bernstein Lawrence R | Local administration of gallium compositions to treat pain |
| EP2413698A4 (en) * | 2009-03-30 | 2013-07-10 | Niiki Pharma Inc | PROCESS FOR TREATING OSTEOPOROSIS |
| WO2011100642A2 (en) * | 2010-02-12 | 2011-08-18 | Niiki Pharma Inc. | Method for treating hematological cancers |
| CN103108636A (zh) * | 2010-02-26 | 2013-05-15 | 尼基制药公司 | 治疗脑癌的方法 |
| CN102946879B (zh) * | 2010-04-19 | 2015-04-22 | 尼基制药公司 | 一种蛋白酶体抑制剂和镓络合物在制备治疗增殖性疾病的药物中的应用 |
| CA2831206A1 (en) * | 2010-04-23 | 2011-10-27 | Niiki Pharma Inc. | Method for treating pancreatic cancer |
| JP6112512B2 (ja) * | 2010-12-01 | 2017-04-12 | レクシ ファーマ インコーポレイテッド | 難治性癌を治療するための方法 |
| US20120245135A1 (en) | 2011-03-24 | 2012-09-27 | Genta Incorporated | Gallium Complexes, Pharmaceutical Compositions And Methods Of Use |
| CN113372269A (zh) * | 2021-06-25 | 2021-09-10 | 云南大学 | 一种席夫碱镓配合物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4373223A (en) * | 1980-01-29 | 1983-02-15 | Mildoy Enterprises | Container opener |
| DE3376387D1 (en) * | 1982-10-22 | 1988-06-01 | Sloan Kettering Inst Cancer | The use of gallium salts for the manufacture of pharmaceutical compositions for the treatment of disorders of calcium homeostasis |
| DE3240377A1 (de) * | 1982-11-02 | 1984-05-03 | Racek, Alfred, 1160 Wien | Feuerzeug |
-
1992
- 1992-07-23 DE DE69225484T patent/DE69225484T2/de not_active Expired - Fee Related
- 1992-07-23 US US08/178,241 patent/US5525598A/en not_active Expired - Lifetime
- 1992-07-23 JP JP50260693A patent/JP3480498B2/ja not_active Expired - Fee Related
- 1992-07-23 ES ES92916381T patent/ES2120450T3/es not_active Expired - Lifetime
- 1992-07-23 AT AT92916381T patent/ATE166056T1/de not_active IP Right Cessation
- 1992-07-23 AU AU23600/92A patent/AU2360092A/en not_active Abandoned
- 1992-07-23 CA CA002114136A patent/CA2114136C/en not_active Expired - Lifetime
- 1992-07-23 EP EP92916381A patent/EP0599881B1/en not_active Expired - Lifetime
- 1992-07-23 WO PCT/EP1992/001687 patent/WO1993002087A1/en active Search and Examination
-
1998
- 1998-08-12 GR GR980401812T patent/GR3027634T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3480498B2 (ja) | 2003-12-22 |
| EP0599881A1 (en) | 1994-06-08 |
| CA2114136A1 (en) | 1993-02-04 |
| DE69225484D1 (de) | 1998-06-18 |
| AU2360092A (en) | 1993-02-23 |
| ATE166056T1 (de) | 1998-05-15 |
| DE69225484T2 (de) | 1998-12-10 |
| ES2120450T3 (es) | 1998-11-01 |
| WO1993002087A1 (en) | 1993-02-04 |
| EP0599881B1 (en) | 1998-05-13 |
| CA2114136C (en) | 2003-07-29 |
| US5525598A (en) | 1996-06-11 |
| JPH07500575A (ja) | 1995-01-19 |
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