ES8307242A1 - Un procedimiento para la preparacion de 3(2-(3-alquil y alquenil-4-piperidil))indoles. - Google Patents
Un procedimiento para la preparacion de 3(2-(3-alquil y alquenil-4-piperidil))indoles.Info
- Publication number
- ES8307242A1 ES8307242A1 ES512472A ES512472A ES8307242A1 ES 8307242 A1 ES8307242 A1 ES 8307242A1 ES 512472 A ES512472 A ES 512472A ES 512472 A ES512472 A ES 512472A ES 8307242 A1 ES8307242 A1 ES 8307242A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- alcenyl
- indoles
- piperidyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 3-(2-(3-ALQUIL Y ALQUENIL-4- -PIPERIDIL)) INDOLES. SE HACE REACCIONAR UN DERIVADO DEL INDOL (II) EN QUE X ES UN ATOMO DE HIDROGENO O DE HALOGENO CON UN DERIVADO METALICO R H EN QUE R ES UN GRUPO ALQUILO, ARILO O DIALQUILAMINO, EL 3-LITIO INDOL OBTENIDO, SE HACE REACCIONAR CON EL DERIVADO DE PIPERIDINA (III) EN QUE R ES UN GRUPO ALQUILO O ALQUENILO CON 1 A 3 ATOMOS DE CARBONO; POR ULTIMO SE HIDROLIZA EL 3-(2-(1-BENZOIL ALQUIL-O 3-ALQUENIL H-PIPERIDIL)ETIL)INDO OBTENIDO. SE OBTIENE EL COMPUESTO (I) EN QUE X ES HIDROGENO O HALOGENO Y R ES ALQUILO O ALQUENILO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8110219A FR2506310A1 (fr) | 1981-05-22 | 1981-05-22 | ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
ES512472A0 ES512472A0 (es) | 1983-07-01 |
ES8307242A1 true ES8307242A1 (es) | 1983-07-01 |
Family
ID=9258781
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512472A Expired ES8307242A1 (es) | 1981-05-22 | 1982-05-21 | Un procedimiento para la preparacion de 3(2-(3-alquil y alquenil-4-piperidil))indoles. |
ES521432A Expired ES8402284A1 (es) | 1981-05-22 | 1983-04-13 | Un procedimiento para la preparacion de indoles. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES521432A Expired ES8402284A1 (es) | 1981-05-22 | 1983-04-13 | Un procedimiento para la preparacion de indoles. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4435410A (es) |
EP (1) | EP0065908B1 (es) |
JP (1) | JPS57200385A (es) |
AR (1) | AR231290A1 (es) |
AU (1) | AU550319B2 (es) |
CA (1) | CA1183849A (es) |
DE (1) | DE3261441D1 (es) |
DK (1) | DK230282A (es) |
ES (2) | ES8307242A1 (es) |
FR (1) | FR2506310A1 (es) |
GR (1) | GR74753B (es) |
HU (1) | HU188172B (es) |
IL (1) | IL65512A (es) |
MA (1) | MA19481A1 (es) |
NO (1) | NO821700L (es) |
PT (1) | PT74916B (es) |
ZA (1) | ZA823489B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3430284A1 (de) * | 1984-08-17 | 1986-02-27 | Troponwerke GmbH & Co KG, 5000 Köln | Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung |
FR2634207B1 (fr) * | 1988-07-12 | 1990-09-07 | Synthelabo | Derives de ((piperidinyl-4)methyl) benzazepines, leur preparation et leur application en therapeutique |
EP0351283A1 (fr) * | 1988-07-12 | 1990-01-17 | Synthelabo | Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1289690A (fr) * | 1960-04-01 | 1962-04-06 | Irwin | Dérivés de l'indole |
GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
GB1023781A (en) * | 1962-02-01 | 1966-03-23 | Benger Lab Ltd | Substituted indoles and their preparation |
US3445472A (en) * | 1965-12-03 | 1969-05-20 | American Home Prod | Mono- and di-aroyl pyridylethyl and piperidylethyl indoles |
FR2334358A1 (fr) | 1975-12-12 | 1977-07-08 | Sogeras | Nouveaux medicaments derives de l'indole |
US4208417A (en) * | 1978-06-29 | 1980-06-17 | Pharmindustrie | Indole derivatives and their use as anxiolytics |
-
1981
- 1981-05-22 FR FR8110219A patent/FR2506310A1/fr active Granted
-
1982
- 1982-04-16 IL IL65512A patent/IL65512A/xx unknown
- 1982-05-03 CA CA000402161A patent/CA1183849A/fr not_active Expired
- 1982-05-03 US US06/374,366 patent/US4435410A/en not_active Expired - Fee Related
- 1982-05-04 GR GR68056A patent/GR74753B/el unknown
- 1982-05-11 EP EP82400872A patent/EP0065908B1/fr not_active Expired
- 1982-05-11 DE DE8282400872T patent/DE3261441D1/de not_active Expired
- 1982-05-18 PT PT74916A patent/PT74916B/pt unknown
- 1982-05-19 ZA ZA823489A patent/ZA823489B/xx unknown
- 1982-05-19 AR AR289454A patent/AR231290A1/es active
- 1982-05-20 MA MA19687A patent/MA19481A1/fr unknown
- 1982-05-21 ES ES512472A patent/ES8307242A1/es not_active Expired
- 1982-05-21 DK DK230282A patent/DK230282A/da not_active Application Discontinuation
- 1982-05-21 AU AU84042/82A patent/AU550319B2/en not_active Ceased
- 1982-05-21 NO NO821700A patent/NO821700L/no unknown
- 1982-05-21 JP JP57086383A patent/JPS57200385A/ja active Pending
- 1982-05-21 HU HU821642A patent/HU188172B/hu unknown
-
1983
- 1983-04-13 ES ES521432A patent/ES8402284A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU550319B2 (en) | 1986-03-20 |
AR231290A1 (es) | 1984-10-31 |
ES512472A0 (es) | 1983-07-01 |
DE3261441D1 (en) | 1985-01-17 |
US4435410A (en) | 1984-03-06 |
IL65512A0 (en) | 1982-07-30 |
NO821700L (no) | 1982-11-23 |
JPS57200385A (en) | 1982-12-08 |
FR2506310A1 (fr) | 1982-11-26 |
EP0065908A1 (fr) | 1982-12-01 |
HU188172B (en) | 1986-03-28 |
PT74916B (fr) | 1983-12-07 |
ES521432A0 (es) | 1984-01-16 |
CA1183849A (fr) | 1985-03-12 |
ZA823489B (en) | 1983-03-30 |
AU8404282A (en) | 1982-11-25 |
IL65512A (en) | 1985-03-31 |
FR2506310B1 (es) | 1984-03-09 |
PT74916A (fr) | 1982-06-01 |
MA19481A1 (fr) | 1982-12-31 |
EP0065908B1 (fr) | 1984-12-05 |
ES8402284A1 (es) | 1984-01-16 |
GR74753B (es) | 1984-07-11 |
DK230282A (da) | 1982-11-23 |
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