GR3026526T3 - Use of antibody-containing preparations for immunosuppression. - Google Patents

Use of antibody-containing preparations for immunosuppression.

Info

Publication number
GR3026526T3
GR3026526T3 GR980400710T GR980400710T GR3026526T3 GR 3026526 T3 GR3026526 T3 GR 3026526T3 GR 980400710 T GR980400710 T GR 980400710T GR 980400710 T GR980400710 T GR 980400710T GR 3026526 T3 GR3026526 T3 GR 3026526T3
Authority
GR
Greece
Prior art keywords
immunosuppression
antibody
containing preparations
preparations
vcd44
Prior art date
Application number
GR980400710T
Other languages
Greek (el)
English (en)
Inventor
Margot Zoeller
Peter Herrlich
Helmut Ponta
Original Assignee
Kernforschungsz Karlsruhe
Deutsches Krebsforsch
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsz Karlsruhe, Deutsches Krebsforsch, Boehringer Ingelheim Int filed Critical Kernforschungsz Karlsruhe
Publication of GR3026526T3 publication Critical patent/GR3026526T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GR980400710T 1991-10-23 1998-04-03 Use of antibody-containing preparations for immunosuppression. GR3026526T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4134982A DE4134982A1 (de) 1991-10-23 1991-10-23 Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression

Publications (1)

Publication Number Publication Date
GR3026526T3 true GR3026526T3 (en) 1998-07-31

Family

ID=6443260

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400710T GR3026526T3 (en) 1991-10-23 1998-04-03 Use of antibody-containing preparations for immunosuppression.

Country Status (17)

Country Link
US (1) US5951982A (cg-RX-API-DMAC10.html)
EP (1) EP0538754B1 (cg-RX-API-DMAC10.html)
JP (1) JPH05310596A (cg-RX-API-DMAC10.html)
KR (1) KR100252620B1 (cg-RX-API-DMAC10.html)
AT (1) ATE162079T1 (cg-RX-API-DMAC10.html)
AU (1) AU659687B2 (cg-RX-API-DMAC10.html)
CA (1) CA2081150C (cg-RX-API-DMAC10.html)
DE (2) DE4134982A1 (cg-RX-API-DMAC10.html)
DK (1) DK0538754T3 (cg-RX-API-DMAC10.html)
ES (1) ES2111031T3 (cg-RX-API-DMAC10.html)
GR (1) GR3026526T3 (cg-RX-API-DMAC10.html)
HU (1) HU216020B (cg-RX-API-DMAC10.html)
IL (1) IL103510A0 (cg-RX-API-DMAC10.html)
NO (1) NO311965B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ244851A (cg-RX-API-DMAC10.html)
TW (1) TW273514B (cg-RX-API-DMAC10.html)
ZA (1) ZA928162B (cg-RX-API-DMAC10.html)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589458A (en) * 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
EP0703989B1 (en) 1993-06-18 1997-11-05 Oy Biotie Therapies COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6
DE4326573A1 (de) * 1993-08-07 1995-02-23 Boehringer Ingelheim Int Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren
DE4431297A1 (de) * 1994-09-02 1996-03-07 Boehringer Ingelheim Int Monoklonaler Antikörper gegen CD44v6
DE19540515C1 (de) * 1995-10-31 1997-02-06 Boehringer Ingelheim Int Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
EP0881299A4 (en) * 1996-02-15 2004-12-15 Chugai Seiyakukabushiki Kaisha MONOCLONAL ANTIBODY THAT RECOGNIZES ANTIGENS ON THE SURFACE OF ENDOTHEL CELLS FROM TUMOR SUPPLYING BLOOD VESSELS.
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
DE19652815C2 (de) * 1996-12-18 1999-11-11 Karlsruhe Forschzent Mittel zur Identifizierung und Therapie metastasierender Tumore
DE19653607A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Int Verfahren zur Diagnose und Therapie von Hodgkin-Lymphomen
DE19708713C2 (de) * 1997-03-04 2002-11-28 Boehringer Ingelheim Int Verwendung von anti-CD44 Antikörpern enthaltenden Präparationen zur Behandlung bestimmter Tumore und zur Unterdrückung von Immunreaktionen
IL121656A0 (en) * 1997-08-29 1998-02-08 Yissum Res Dev Co Diagnosis prevention and treatment of diabetes
US7534605B2 (en) 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
WO2004024750A2 (en) * 2002-09-13 2004-03-25 Dyax Corporation Cd44-binding ligands
US9701754B1 (en) 2002-10-23 2017-07-11 City Of Hope Covalent disulfide-linked diabodies and uses thereof
US20070280930A1 (en) * 2004-03-17 2007-12-06 Kasper Mathias Antoon Rouschop Cd44-Targeting for Reducing/Preventing Ischemia-Reperfusion-Injury
EP2267030A1 (en) 2005-08-25 2010-12-29 Repair Technologies, Inc. Devices, compositions and methods for the protection and repair of cells and tissues
ATE509033T1 (de) 2006-03-20 2011-05-15 Univ California Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
WO2009032949A2 (en) 2007-09-04 2009-03-12 The Regents Of The University Of California High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
EP2398504B1 (en) 2009-02-17 2018-11-28 Cornell Research Foundation, Inc. Methods and kits for diagnosis of cancer and prediction of therapeutic value
AU2010325969B2 (en) 2009-12-02 2016-10-20 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
EP2886126B1 (en) 2013-12-23 2017-06-07 Exchange Imaging Technologies GmbH Nanoparticle conjugated to CD44 binding peptides
HUE049261T2 (hu) 2014-07-15 2020-09-28 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd CD44 izolált polipeptidek és alkalmazásaik
EP3331564B1 (en) 2015-08-07 2025-01-08 Imaginab, Inc. Antigen binding constructs to target molecules
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies
US11313243B2 (en) 2018-07-12 2022-04-26 Rolls-Royce North American Technologies, Inc. Non-continuous abradable coatings

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0303463B1 (en) * 1987-08-11 1994-11-30 The Board Of Trustees Of The Leland Stanford Junior University Method to control leukocyte extravasation
DE4014510A1 (de) * 1990-05-07 1991-11-14 Kernforschungsz Karlsruhe Variante cd44-oberflaechenproteine, diese kodierende c-dna-sequenzen, antikoerper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie
CA2059824A1 (en) * 1991-02-26 1992-08-27 Thomas M. Aune Hybridomas and monoclonal antibodies that inhibit anti-cd3-stimulated t cell proliferation
EP0703989B1 (en) * 1993-06-18 1997-11-05 Oy Biotie Therapies COMPOSITIONS AND DIAGNOSTIC METHODS USING MONOCLONAL ANTIBODIES AGAINST CD44v6

Also Published As

Publication number Publication date
CA2081150C (en) 2001-04-10
DK0538754T3 (da) 1998-03-30
IL103510A0 (en) 1993-03-15
AU659687B2 (en) 1995-05-25
NO924103D0 (no) 1992-10-22
ZA928162B (en) 1993-05-05
ES2111031T3 (es) 1998-03-01
TW273514B (cg-RX-API-DMAC10.html) 1996-04-01
DE59209129D1 (de) 1998-02-19
DE4134982A1 (de) 1993-04-29
HU216020B (hu) 1999-04-28
EP0538754A3 (en) 1994-05-25
NO311965B1 (no) 2002-02-25
KR930007460A (ko) 1993-05-20
EP0538754B1 (de) 1998-01-14
ATE162079T1 (de) 1998-01-15
US5951982A (en) 1999-09-14
EP0538754A2 (de) 1993-04-28
HUT63063A (en) 1993-07-28
CA2081150A1 (en) 1993-04-24
JPH05310596A (ja) 1993-11-22
NO924103L (no) 1993-04-26
AU2724492A (en) 1993-04-29
KR100252620B1 (ko) 2000-09-01
NZ244851A (en) 1997-07-27

Similar Documents

Publication Publication Date Title
EP0538754A3 (en) Use of antibody-containing preparations for immunosuppression
TW218869B (cg-RX-API-DMAC10.html)
GR3034332T3 (en) Protein purification.
GB9415380D0 (en) Recombinant antibodies specific for tnf-
GB8719587D0 (en) Monoclonal antibodies & peptides
AU6080794A (en) Antibodies directed against binding-associated epitopes
FI945865A7 (fi) Glykoprofeiini P:lle kohdistettuja monoklonaalisia vasta-aineita
EP0578515A3 (en) Humanized monoclonal antibodies.
DK0638068T3 (da) Fremgangsmåde til fremstilling af (S)-3-amino-1-substitueret-pyrrolidiner
IL90220A0 (en) Anticoagulant peptide alcohols
EP0506523A3 (en) Monoclonal antibodies
DK0585570T3 (da) Granulocytbindende antistofkonstrukter, deres fremstilling og anvendelse
AU1025692A (en) Novel chimeric antiidiotypic monoclonal antibodies
EP0511300A4 (en) Monoclonal antibody specific for non-immunodominant epitope of hiv proteins
GB9011589D0 (en) Amino bicyclic compounds
IT1246852B (it) Corpo composito per rubinetti
AU2629792A (en) Process for the purification of streptolysin 0, intact streptolysin 0 obtained by this process and its use
ITBS920112A0 (it) Corpo composito per rubinetti
FI941394A0 (fi) Peptidejä,jotka kykenevät säätelemään akrosomireaktiota
ITMI910660A0 (it) Anticorpi monoclonali come antidoti
GB9222707D0 (en) Antigens for immunisation
GB9225853D0 (en) Antigen-binding proteins
SG64332A1 (en) Monoclonal antibody
GB9212074D0 (en) Monoclonal antibody
SG49856A1 (en) Reshaped monoclonal antibodies againts an immunobulin isotype