GR3026228T3 - Tropone-substituted phenyloxazolidinone antibacterial agents. - Google Patents
Tropone-substituted phenyloxazolidinone antibacterial agents.Info
- Publication number
- GR3026228T3 GR3026228T3 GR980400408T GR980400408T GR3026228T3 GR 3026228 T3 GR3026228 T3 GR 3026228T3 GR 980400408 T GR980400408 T GR 980400408T GR 980400408 T GR980400408 T GR 980400408T GR 3026228 T3 GR3026228 T3 GR 3026228T3
- Authority
- GR
- Greece
- Prior art keywords
- antibacterial agents
- tropone
- substituted
- substituted phenyloxazolidinone
- phenyloxazolidinone antibacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98858992A | 1992-12-08 | 1992-12-08 | |
US377893A | 1993-01-13 | 1993-01-13 | |
US6635693A | 1993-05-21 | 1993-05-21 | |
PCT/US1993/009589 WO1994013649A1 (en) | 1992-12-08 | 1993-10-14 | Tropone-substituted phenyloxazolidinone antibacterial agents |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3026228T3 true GR3026228T3 (en) | 1998-05-29 |
Family
ID=27357482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980400408T GR3026228T3 (en) | 1992-12-08 | 1998-02-25 | Tropone-substituted phenyloxazolidinone antibacterial agents. |
Country Status (20)
Country | Link |
---|---|
US (1) | US5523403A (el) |
EP (1) | EP0673370B1 (el) |
JP (1) | JP3558088B2 (el) |
KR (1) | KR100276382B1 (el) |
AT (1) | ATE161833T1 (el) |
AU (1) | AU670842B2 (el) |
CA (1) | CA2147753C (el) |
CZ (1) | CZ288788B6 (el) |
DE (1) | DE69316240T2 (el) |
DK (1) | DK0673370T3 (el) |
ES (1) | ES2111188T3 (el) |
FI (1) | FI952798A (el) |
GR (1) | GR3026228T3 (el) |
HU (1) | HUT74099A (el) |
NO (1) | NO952253L (el) |
NZ (1) | NZ257031A (el) |
PL (1) | PL175782B1 (el) |
RU (1) | RU2119484C1 (el) |
SK (1) | SK282453B6 (el) |
WO (1) | WO1994013649A1 (el) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668286A (en) * | 1994-03-15 | 1997-09-16 | Pharmacia & Upjohn Company | Oxazolidinone derivatives and pharmaceutical compositions containing them |
WO1997010235A1 (en) * | 1995-09-15 | 1997-03-20 | Pharmacia & Upjohn Company | 5-AMIDOMETHYL α, β-SATURATED AND -UNSATURATED 3-ARYL BUTYROLACTONE ANTIBACTERIAL AGENTS |
GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
GB9609919D0 (en) * | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
EP0920421B1 (en) * | 1996-08-21 | 2002-11-06 | PHARMACIA & UPJOHN COMPANY | Isoxazoline derivatives useful as antimicrobials |
US5998414A (en) * | 1996-08-22 | 1999-12-07 | Hoechst Marion Roussel, Inc. | Troponyl piperazines as dopamine D4 receptor ligands |
GB9717807D0 (en) * | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
HUP0004388A3 (en) * | 1997-11-07 | 2001-10-29 | Upjohn Co | Process for the preparation of oxazolidinones, intermediates and preparation thereof |
GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
US6083967A (en) * | 1997-12-05 | 2000-07-04 | Pharmacia & Upjohn Company | S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones |
WO1999037630A1 (en) * | 1998-01-23 | 1999-07-29 | Versicor, Inc. | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
BR9910971A (pt) | 1998-06-05 | 2001-02-13 | Astrazeneca Ab | Composto, processos para a preparação de um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica |
US6420349B1 (en) | 1998-08-24 | 2002-07-16 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
TW572757B (en) * | 1998-08-24 | 2004-01-21 | Bristol Myers Squibb Co | Novel isoxazolinone antibacterial agents |
JP2002535680A (ja) | 1999-01-27 | 2002-10-22 | ファルマシア・アンド・アップジョン・カンパニー | 延長因子p活性モジュレーターのアッセイ方法 |
GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
US6465456B2 (en) | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
EP1349853B1 (en) * | 2000-12-21 | 2006-03-08 | Pharmacia & Upjohn Company LLC | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
DE60206154T2 (de) * | 2001-04-17 | 2006-06-29 | Merck & Co., Inc. | Bicyclo[3,1,0]hexan als strukturelement enthaltende oxazolidinon-antibiotika und deren derivate |
TW200302095A (en) * | 2002-01-25 | 2003-08-01 | Upjohn Co | Oxazolidinone cotherapy |
EP1472247A1 (en) | 2002-02-05 | 2004-11-03 | PHARMACIA & UPJOHN COMPANY | Antimicrobial thiadiazinone derivatives useful in treatment of bacterial infections |
AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
MXPA04009356A (es) * | 2002-03-29 | 2005-01-25 | Pharmacia & Upjohn Co Llc | Administracion parenteral, intravenosa y oral de oxazolidinonas para tratar infecciones de pie diabetico. |
CA2491287A1 (en) * | 2002-08-12 | 2004-02-19 | Pharmacia & Upjohn Company | N-aryl-2-oxazolidinones and their derivatives |
ATE344036T1 (de) * | 2002-11-21 | 2006-11-15 | Pharmacia & Upjohn Co Llc | N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel |
US8050281B2 (en) * | 2003-01-31 | 2011-11-01 | Qwest Communications International Inc. | Alert gateway, systems and methods |
US8813142B2 (en) * | 2003-01-31 | 2014-08-19 | Qwest Communications International Inc. | Methods, systems and apparatus for providing video transmissions over multiple media |
US7474742B2 (en) * | 2003-01-31 | 2009-01-06 | Qwest Communications International Inc. | Environmentally-controlled network interface device and methods |
WO2004069832A2 (en) * | 2003-02-07 | 2004-08-19 | Warner-Lambert Company Llc | Antibacterial agents |
US20040204463A1 (en) * | 2003-04-01 | 2004-10-14 | Harris Christina Renee | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
AR045690A1 (es) * | 2003-06-03 | 2005-11-09 | Rib X Pharmaceuticals Inc | Compuestos biaril heterociclicos y metodos para preparar y utilizar los mismos |
US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
CA2529292A1 (en) * | 2003-07-02 | 2005-01-20 | Merck & Co., Inc. | Oxazolidinone antibiotics and derivatives thereof |
WO2005005422A1 (en) * | 2003-07-02 | 2005-01-20 | Merck & Co., Inc. | Oxazolidinone antibiotics and derivatives thereof |
KR20060113625A (ko) * | 2003-07-02 | 2006-11-02 | 머크 앤드 캄파니 인코포레이티드 | 시클로프로필기 치환된 옥사졸리디논 항생제 및 그의유도체 |
CA2529293A1 (en) * | 2003-07-02 | 2005-01-20 | Merck & Co., Inc. | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
BRPI0413838A (pt) * | 2003-08-25 | 2006-10-24 | Warner Lambert Co | compostos de ariloxazolidinona antimicrobianos |
US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
WO2005061468A1 (en) * | 2003-12-17 | 2005-07-07 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
US8399660B2 (en) | 2005-06-08 | 2013-03-19 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of triazoles |
CA2647605A1 (en) * | 2006-03-31 | 2007-10-11 | Research Foundation Itsuu Laboratory | Novel compound having heterocyclic ring |
JPWO2007116960A1 (ja) * | 2006-04-06 | 2009-08-20 | 財団法人乙卯研究所 | 炭素環を有するオキサゾリジノン誘導体 |
EP2208729A4 (en) | 2007-10-02 | 2011-04-27 | Res Found Itsuu Lab | OXAZOLIDINONE DERIVATIVE WITH 7-CHAIN HETEROCYCLE |
WO2010042887A2 (en) | 2008-10-10 | 2010-04-15 | Trius Therapeutics | Methods for preparing oxazolidinones and compositions containing them |
PE20120585A1 (es) | 2009-02-03 | 2012-06-13 | Trius Therapeutics | Forma cristalina del fosfato de dihidrogeno r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofensil)-5-hidroximetil oxazolidin-2-ona |
US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE29607E (en) * | 1969-03-18 | 1978-04-11 | Delalande S. A. | Derivatives of 5-hydroxymethyl-3-substituted-2-oxazolidinones, process of preparation thereof and therapeutic application |
LU80081A1 (fr) * | 1977-08-26 | 1979-05-15 | Delalande Sa | Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique |
US4128654A (en) * | 1978-02-10 | 1978-12-05 | E. I. Du Pont De Nemours And Company | 5-Halomethyl-3-phenyl-2-oxazolidinones |
US4340606A (en) * | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
FR2500450A1 (fr) * | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
DE3149608A1 (de) * | 1981-12-15 | 1983-08-04 | Dr. Madaus & Co, 5000 Köln | Substituierte tropolone, verfahren zur herstellung derselben und diese enthaltende pharmazeutische zubereitungen |
US4461773A (en) * | 1982-09-15 | 1984-07-24 | E. I. Dupont De Nemours And Company | P-Oxooxazolidinylbenzene compounds as antibacterial agents |
ES8506659A1 (es) * | 1983-06-07 | 1985-08-01 | Du Pont | Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno. |
US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
CA1260948A (en) * | 1984-12-05 | 1989-09-26 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents |
US4921869A (en) * | 1987-10-09 | 1990-05-01 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
US4801600A (en) * | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
CA1317594C (en) * | 1987-10-21 | 1993-05-11 | Chung-Ho Park | Aminomethyloxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents |
US4977173A (en) * | 1987-10-21 | 1990-12-11 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents |
US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
-
1993
- 1993-10-14 DK DK93923304T patent/DK0673370T3/da active
- 1993-10-14 DE DE69316240T patent/DE69316240T2/de not_active Expired - Fee Related
- 1993-10-14 SK SK746-95A patent/SK282453B6/sk unknown
- 1993-10-14 NZ NZ257031A patent/NZ257031A/en unknown
- 1993-10-14 WO PCT/US1993/009589 patent/WO1994013649A1/en active IP Right Grant
- 1993-10-14 JP JP51413894A patent/JP3558088B2/ja not_active Expired - Fee Related
- 1993-10-14 KR KR1019950702303A patent/KR100276382B1/ko not_active IP Right Cessation
- 1993-10-14 AT AT93923304T patent/ATE161833T1/de not_active IP Right Cessation
- 1993-10-14 CZ CZ19951366A patent/CZ288788B6/cs not_active IP Right Cessation
- 1993-10-14 EP EP93923304A patent/EP0673370B1/en not_active Expired - Lifetime
- 1993-10-14 CA CA002147753A patent/CA2147753C/en not_active Expired - Fee Related
- 1993-10-14 HU HU9501670A patent/HUT74099A/hu unknown
- 1993-10-14 RU RU95114378A patent/RU2119484C1/ru not_active IP Right Cessation
- 1993-10-14 ES ES93923304T patent/ES2111188T3/es not_active Expired - Lifetime
- 1993-10-14 AU AU53239/94A patent/AU670842B2/en not_active Ceased
- 1993-10-14 PL PL93309283A patent/PL175782B1/pl not_active IP Right Cessation
-
1995
- 1995-05-22 US US08/445,594 patent/US5523403A/en not_active Expired - Fee Related
- 1995-06-07 FI FI952798A patent/FI952798A/fi not_active IP Right Cessation
- 1995-06-07 NO NO952253A patent/NO952253L/no unknown
-
1998
- 1998-02-25 GR GR980400408T patent/GR3026228T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CZ288788B6 (cs) | 2001-09-12 |
FI952798A0 (fi) | 1995-06-07 |
AU670842B2 (en) | 1996-08-01 |
CA2147753C (en) | 2004-08-03 |
JPH08504205A (ja) | 1996-05-07 |
SK282453B6 (sk) | 2002-02-05 |
ATE161833T1 (de) | 1998-01-15 |
DK0673370T3 (da) | 1998-09-07 |
DE69316240T2 (de) | 1998-05-20 |
DE69316240D1 (de) | 1998-02-12 |
PL309283A1 (en) | 1995-10-02 |
AU5323994A (en) | 1994-07-04 |
CZ136695A3 (en) | 1995-10-18 |
RU95114378A (ru) | 1997-06-10 |
EP0673370A1 (en) | 1995-09-27 |
US5523403A (en) | 1996-06-04 |
NZ257031A (en) | 1996-07-26 |
FI952798A (fi) | 1995-06-07 |
WO1994013649A1 (en) | 1994-06-23 |
KR100276382B1 (ko) | 2000-12-15 |
HUT74099A (en) | 1996-11-28 |
EP0673370B1 (en) | 1998-01-07 |
NO952253D0 (no) | 1995-06-07 |
ES2111188T3 (es) | 1998-03-01 |
CA2147753A1 (en) | 1994-06-23 |
NO952253L (no) | 1995-08-08 |
JP3558088B2 (ja) | 2004-08-25 |
RU2119484C1 (ru) | 1998-09-27 |
PL175782B1 (pl) | 1999-02-26 |
HU9501670D0 (en) | 1995-08-28 |
SK74695A3 (en) | 1995-10-11 |
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