GR3025809T3 - Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors. - Google Patents

Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors.

Info

Publication number
GR3025809T3
GR3025809T3 GR970403456T GR970403456T GR3025809T3 GR 3025809 T3 GR3025809 T3 GR 3025809T3 GR 970403456 T GR970403456 T GR 970403456T GR 970403456 T GR970403456 T GR 970403456T GR 3025809 T3 GR3025809 T3 GR 3025809T3
Authority
GR
Greece
Prior art keywords
alkyl
aryl
halosubstituted
alkoxy
independently
Prior art date
Application number
GR970403456T
Other languages
Greek (el)
English (en)
Inventor
Takafumi Ikeda
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3025809T3 publication Critical patent/GR3025809T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR970403456T 1992-07-23 1997-12-30 Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors. GR3025809T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4197242A JP2661841B2 (ja) 1992-07-23 1992-07-23 インドリン誘導体
PCT/US1993/005391 WO1994002459A1 (en) 1992-07-23 1993-06-10 Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors

Publications (1)

Publication Number Publication Date
GR3025809T3 true GR3025809T3 (en) 1998-03-31

Family

ID=16371216

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970403456T GR3025809T3 (en) 1992-07-23 1997-12-30 Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors.

Country Status (24)

Country Link
EP (1) EP0651743B1 (ja)
JP (1) JP2661841B2 (ja)
KR (1) KR950702533A (ja)
CN (1) CN1085894A (ja)
AT (1) ATE161250T1 (ja)
AU (1) AU675654B2 (ja)
BR (1) BR9306762A (ja)
CA (1) CA2140344C (ja)
CZ (1) CZ15995A3 (ja)
DE (1) DE69315841T2 (ja)
DK (1) DK0651743T3 (ja)
ES (1) ES2110101T3 (ja)
FI (1) FI104068B1 (ja)
GR (1) GR3025809T3 (ja)
HU (1) HUT70182A (ja)
IL (1) IL106359A0 (ja)
MX (1) MX9304441A (ja)
NZ (1) NZ253881A (ja)
PL (1) PL307229A1 (ja)
SK (1) SK8695A3 (ja)
TW (1) TW227556B (ja)
WO (1) WO1994002459A1 (ja)
YU (1) YU50893A (ja)
ZA (1) ZA935304B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8870191A (en) * 1990-10-02 1992-04-28 Stat-Tech International Corporation Electric charge discharge and dissipation device
AU4400597A (en) * 1996-10-08 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
EP1101492A4 (en) * 1998-07-17 2002-09-25 Daiichi Fine Chem Co Ltd MEDICINE AGAINST ALLERGIC DISEASES
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANIN CONCENTRATION HORMONE ANTAGONIST
UA95084C2 (en) * 2005-11-04 2011-07-11 Амира Фармасутикалз, Инк. 5-lipoxygenase-activating protein (flap) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279263B1 (en) * 1987-02-10 1993-08-04 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
IE903206A1 (en) * 1989-09-07 1991-03-13 Abbott Lab Indole-, benzofuran-, and benzothiophene-containing¹lipoxygenase-inhibiting compounds
KR900016822A (ko) * 1990-04-20 1990-11-14 하라 레이노스께 슬라이드 프로젝터
US5132319A (en) * 1991-03-28 1992-07-21 Merck Frosst Canada, Inc. 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
NZ253881A (en) 1996-01-26
PL307229A1 (en) 1995-05-15
BR9306762A (pt) 1998-12-08
ATE161250T1 (de) 1998-01-15
FI933307A (fi) 1994-01-24
HU9302126D0 (en) 1993-10-28
HUT70182A (en) 1995-09-28
EP0651743A1 (en) 1995-05-10
FI104068B (fi) 1999-11-15
YU50893A (sh) 1996-07-24
KR950702533A (ko) 1995-07-29
DK0651743T3 (da) 1998-02-02
FI104068B1 (fi) 1999-11-15
CA2140344C (en) 1997-08-26
AU675654B2 (en) 1997-02-13
CA2140344A1 (en) 1994-02-03
WO1994002459A1 (en) 1994-02-03
CN1085894A (zh) 1994-04-27
ZA935304B (en) 1995-01-23
MX9304441A (es) 1994-07-29
JPH0641068A (ja) 1994-02-15
DE69315841D1 (de) 1998-01-29
ES2110101T3 (es) 1998-02-01
EP0651743B1 (en) 1997-12-17
IL106359A0 (en) 1993-11-15
DE69315841T2 (de) 1998-04-09
AU4529193A (en) 1994-02-14
TW227556B (ja) 1994-08-01
CZ15995A3 (en) 1995-09-13
JP2661841B2 (ja) 1997-10-08
FI933307A0 (fi) 1993-07-22
SK8695A3 (en) 1995-07-11

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