GR3005844T3 - - Google Patents

Info

Publication number
GR3005844T3
GR3005844T3 GR920402178T GR920402178T GR3005844T3 GR 3005844 T3 GR3005844 T3 GR 3005844T3 GR 920402178 T GR920402178 T GR 920402178T GR 920402178 T GR920402178 T GR 920402178T GR 3005844 T3 GR3005844 T3 GR 3005844T3
Authority
GR
Greece
Prior art keywords
aminobenzothiazole
antitumor agents
acyl derivatives
alkylated analogs
alkylated
Prior art date
Application number
GR920402178T
Other languages
Greek (el)
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3005844T3 publication Critical patent/GR3005844T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Graft Or Block Polymers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR920402178T 1988-05-24 1992-09-30 GR3005844T3 (forum.php)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19803488A 1988-05-24 1988-05-24

Publications (1)

Publication Number Publication Date
GR3005844T3 true GR3005844T3 (forum.php) 1993-06-07

Family

ID=22731735

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920402178T GR3005844T3 (forum.php) 1988-05-24 1992-09-30

Country Status (25)

Country Link
EP (1) EP0343893B1 (forum.php)
JP (1) JPH0678331B2 (forum.php)
KR (1) KR910006864B1 (forum.php)
CN (1) CN1023700C (forum.php)
AT (1) ATE79114T1 (forum.php)
AU (1) AU601905B2 (forum.php)
CA (1) CA1328871C (forum.php)
DD (1) DD283815A5 (forum.php)
DE (1) DE68902358T2 (forum.php)
DK (1) DK249389A (forum.php)
ES (1) ES2043012T3 (forum.php)
FI (1) FI892498A7 (forum.php)
GR (1) GR3005844T3 (forum.php)
HU (1) HU202507B (forum.php)
IE (1) IE891667L (forum.php)
IL (1) IL90337A0 (forum.php)
MX (1) MX173140B (forum.php)
MY (1) MY106035A (forum.php)
NO (1) NO172389C (forum.php)
NZ (1) NZ229234A (forum.php)
PL (1) PL154875B1 (forum.php)
PT (1) PT90622B (forum.php)
SU (1) SU1681728A3 (forum.php)
YU (1) YU47019B (forum.php)
ZA (1) ZA893862B (forum.php)

Families Citing this family (38)

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JP2790299B2 (ja) * 1989-02-01 1998-08-27 保土谷化学工業株式会社 ペンゾチアゾール誘導体
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US6100423A (en) * 1995-08-30 2000-08-08 G. D. Searle & Co. Amino benzenepropanoic acid compounds and derivatives thereof
RU2196769C2 (ru) * 1995-08-30 2003-01-20 Джи. Ди. Сирл Энд Ко. Производные аминобензойной кислоты, фармацевтическая композиция
US5716281A (en) * 1995-11-27 1998-02-10 Sega Enterprises, Ltd. Game apparatus using a vehicle with an optical image synthesizing system
TW513418B (en) * 1996-07-31 2002-12-11 Otsuka Pharma Co Ltd Thiazole derivatives, their production and use
PL340727A1 (en) 1997-11-10 2001-02-26 Bristol Myers Squibb Co Benzothiazolic inhibitors of proteinous thyrosinic kinase
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
AU3406599A (en) * 1998-04-09 1999-11-01 Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis
ATE385794T1 (de) 2000-06-21 2008-03-15 Hoffmann La Roche Benzothiazolderivate zur behandlung von alzheimer und parkinson
US6620811B2 (en) * 2001-11-19 2003-09-16 Hoffmann-La Roche Inc. Isonicotin- and nicotinamide derivatives of benzothiazoles
US6599901B1 (en) * 2001-11-19 2003-07-29 Hoffman-La Roche Inc. Pyridone substituted benzothiazole derivatives
US6624163B2 (en) 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
GB0130868D0 (en) 2001-12-24 2002-02-06 Univ Strathclyde New compounds
CN100357283C (zh) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 一类甲硫氨酰氨肽酶抑制剂
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
ATE407133T1 (de) * 2003-05-13 2008-09-15 Hoffmann La Roche 2-imidazo-benzothiazole als adenosin-rezeptor liganden
BRPI0410440A (pt) * 2003-05-19 2006-06-06 Hoffmann La Roche derivados de benzotiazol como ligandos de receptor de adenosina
KR100765565B1 (ko) * 2003-05-21 2007-10-09 에프. 호프만-라 로슈 아게 벤조티아졸 유도체 및 그의 아데노신 에이2에이 수용체에관련된 질병의 치료에서의 용도
PL1633355T3 (pl) * 2003-05-30 2008-10-31 Hoffmann La Roche Pochodne benzotiazolu i ich zastosowanie w leczeniu chorób związanych z receptorem adenozynowym A2A
JP4726238B2 (ja) * 2003-07-28 2011-07-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ベンズイミダゾール、ベンズチアゾールおよびベンゾキサゾール誘導体およびlta4hモジュレーターとしてのそれらの使用
EA011279B1 (ru) 2004-05-24 2009-02-27 Ф. Хоффманн-Ля Рош Аг (4-метокси-7-морфолин-4-илбензотиазол-2-ил)-амид 4-гидрокси-4-метилпиперидин-1-карбоновой кислоты
CN1989139B (zh) * 2004-07-22 2010-05-12 弗·哈夫曼-拉罗切有限公司 苯并噻唑衍生物
CN1989117B (zh) * 2004-07-22 2011-01-19 弗·哈夫曼-拉罗切有限公司 取代的苯并噻唑
ES2309814T3 (es) 2004-11-05 2008-12-16 F. Hoffmann-La Roche Ag Proceso para la obtencion de derivados del acido isonicotinico.
PL1863818T3 (pl) 2005-03-23 2010-08-31 Hoffmann La Roche Pochodne acetylenylo-pirazolo-pirymidyny jako antagoniści MGLUR2
JP5048675B2 (ja) 2005-09-27 2012-10-17 エフ.ホフマン−ラ ロシュ アーゲー mGluR2アンタゴニストとしてのオキサジアゾリルピラゾロ−ピリミジン類
EP1994017A2 (en) * 2006-03-15 2008-11-26 4Sc Ag Novel heterocyclic nf-kb inhibitors
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
EP2311842A3 (en) * 2008-06-24 2011-07-13 Takeda Pharmaceutical Company Limited PI3K/M TOR inhibitors
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
WO2013049407A2 (en) * 2011-09-30 2013-04-04 Kineta, Inc Anti-viral compounds
KR101996343B1 (ko) 2012-01-27 2019-07-05 고쿠리츠 다이가쿠 호진 교토 다이가쿠 전능성 줄기세포의 심근분화 유도방법
US10196609B2 (en) 2013-03-08 2019-02-05 Kyoto University Composition for promoting cardiac differentiation of pluripotent stem cell comprising EGFR inhibitor
EP3045451B1 (en) * 2013-09-13 2018-03-28 Kyoto University Compound promoting differentiation of pluripotent stem cells into cardiomyocytes
US10233426B2 (en) 2014-05-30 2019-03-19 Kyoto University Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds
CN109776486A (zh) * 2019-02-26 2019-05-21 武汉松石科技股份有限公司 一种硫酸亚丙酯的制备方法
CN110590735B (zh) * 2019-09-30 2021-07-23 江苏国泰超威新材料有限公司 一种环状硫酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61225168A (ja) * 1985-03-30 1986-10-06 Nippon Tokushu Noyaku Seizo Kk 新規ベンズアミド、その製法及び殺虫剤
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8611606D0 (en) * 1986-05-13 1986-06-18 Fbc Ltd Fungicides

Also Published As

Publication number Publication date
SU1681728A3 (ru) 1991-09-30
NO892059L (no) 1989-11-27
DE68902358D1 (de) 1992-09-10
DK249389A (da) 1989-11-27
PT90622B (pt) 1994-10-31
JPH0217181A (ja) 1990-01-22
KR890017248A (ko) 1989-12-15
DD283815A5 (de) 1990-10-24
HU202507B (en) 1991-03-28
IL90337A0 (en) 1989-12-15
KR910006864B1 (ko) 1991-09-09
PT90622A (pt) 1989-11-30
DE68902358T2 (de) 1992-12-10
ATE79114T1 (de) 1992-08-15
YU105989A (en) 1990-08-31
MX16158A (es) 1993-06-01
PL279613A1 (en) 1989-11-27
NO172389C (no) 1993-07-14
JPH0678331B2 (ja) 1994-10-05
ES2043012T3 (es) 1993-12-16
ZA893862B (en) 1991-01-30
CA1328871C (en) 1994-04-26
AU3509889A (en) 1989-11-30
NZ229234A (en) 1990-09-26
PL154875B1 (en) 1991-09-30
IE891667L (en) 1989-11-24
EP0343893B1 (en) 1992-08-05
AU601905B2 (en) 1990-09-20
FI892498A0 (fi) 1989-05-23
MX173140B (es) 1994-02-02
YU47019B (sh) 1994-11-15
HUT51606A (en) 1990-05-28
CN1023700C (zh) 1994-02-09
FI892498A7 (fi) 1989-11-25
DK249389D0 (da) 1989-05-23
CN1037898A (zh) 1989-12-13
NO172389B (no) 1993-04-05
NO892059D0 (no) 1989-05-23
MY106035A (en) 1995-03-31
EP0343893A1 (en) 1989-11-29

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