GR1000743B - Μεθοδος παρασκευης νεων παραγωγων τριαζολο-πυριμιδινης. - Google Patents
Μεθοδος παρασκευης νεων παραγωγων τριαζολο-πυριμιδινης.Info
- Publication number
- GR1000743B GR1000743B GR900100149A GR900100149A GR1000743B GR 1000743 B GR1000743 B GR 1000743B GR 900100149 A GR900100149 A GR 900100149A GR 900100149 A GR900100149 A GR 900100149A GR 1000743 B GR1000743 B GR 1000743B
- Authority
- GR
- Greece
- Prior art keywords
- group
- preparation
- alkyl
- aralkyl
- formulas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Η εφεύρεση αυτή αναφέρεται σε νέα παράγωγα τριαζολοπυριμιδίνης των τύπων (Ια) και (Ιβ), ΧΗΜΙΚΗ ΕΝΩΣΗ όπου Q παριστάνει υδρογόνο μια ετεροκυκλική ομάδα προαιρετικά υποκαταστημένη από μια C1-4 αλκυλ ομάδα και που περιέχει ένα ή περισσότερα άτομα οξυγόνου και/ή αζώτου ή μια ομάδα του τύπου -SR1 όπου R1 είναι αλκύλιο ή αραλκύλιο, ή μια ομάδα του τύπου -NR2R3 όπου R2 και R3 είναι ανεξάρτητα υδρογόνο, αλκύλιο, αλκενύλιο, κυκλοαλκύλιο, αραλκύλιο, αρύλιο ή ετεροκυκλική ομάδα, m και n είναι ανεξάρτητα 1,2,3 ή 4, με την προϋπόθεση ότι όταν m είναι 0, τότε n είναι άλλο από 0, και αν αμφότερα τα m και n είναι 1 ή m είναι 0 και n είναι 2, τότε Q είναι διαφορετικό από μεθυλθειο ή μορφολινο ομάδα, μίγματά τους ή φαρμακευτικά αποδεκτά αλάτια τους. Επιπλέον η εφεύρεση αναφέρεται σε μια μέθοδο για την παρασκευή των ενώσεων αυτών. Οι ενώσεις των τύπων (Ια) και (Ιβ) είναι ικανές να αναστέλλουν την πτώση που προκαλείται από τετραβεναζίνη και έχουν αναλγησιακή ενεργότητα. ω
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU891016A HU205117B (en) | 1989-03-03 | 1989-03-03 | Process for producing new triazolopyrimidine derivatives condensed with sulfur ring, as well as pharmaceutical compositions comprising same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR900100149A GR900100149A (en) | 1990-07-31 |
| GR1000743B true GR1000743B (el) | 1992-12-30 |
Family
ID=10952469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR900100149A GR1000743B (el) | 1989-03-03 | 1990-03-02 | Μεθοδος παρασκευης νεων παραγωγων τριαζολο-πυριμιδινης. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5064826A (el) |
| JP (1) | JPH032185A (el) |
| KR (1) | KR900014395A (el) |
| AT (1) | AT399152B (el) |
| CA (1) | CA2011325A1 (el) |
| CH (1) | CH681454A5 (el) |
| DD (1) | DD292461A5 (el) |
| DE (1) | DE4006873A1 (el) |
| ES (1) | ES2021956A6 (el) |
| FI (1) | FI94344C (el) |
| FR (1) | FR2643904B1 (el) |
| GB (1) | GB2228733B (el) |
| GR (1) | GR1000743B (el) |
| HU (1) | HU205117B (el) |
| IT (1) | IT1241410B (el) |
| NL (1) | NL9000491A (el) |
| PL (1) | PL163565B1 (el) |
| RU (1) | RU1776261C (el) |
| YU (1) | YU47507B (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478825A (en) * | 1991-02-22 | 1995-12-26 | Egis Gyogyszergyar | 5-(substituted amino)-1,2,4-triazolo (1,5-A) pyrimidine derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB627602A (en) * | 1945-12-15 | 1949-08-11 | Gen Aniline & Film Corp | Stabilizers for photographic emulsion |
| GB1070243A (en) * | 1964-07-15 | 1967-06-01 | Smith Kline French Lab | S-triazolopyrimidones, their preparation and compositions containing them |
| US4614743A (en) * | 1983-12-27 | 1986-09-30 | Schering Corporation | Methods of treating pain and inflammation with 4,7-dimethyl-2-(4-pyridinyl)-1,2,4,-triazolo[1,5-a]pyrimidin-5(4H)-one or the pharmaceutically acceptable salts or solvates thereof |
| US4576943A (en) * | 1984-10-09 | 1986-03-18 | American Cyanamid Company | Pyrazolo[1,5-a]pyrimidines |
| US4831013A (en) * | 1986-03-20 | 1989-05-16 | Ciba-Geigy Corporation | 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof |
-
1989
- 1989-03-03 HU HU891016A patent/HU205117B/hu not_active IP Right Cessation
-
1990
- 1990-02-27 KR KR1019900002539A patent/KR900014395A/ko not_active Application Discontinuation
- 1990-03-01 CH CH679/90A patent/CH681454A5/de not_active IP Right Cessation
- 1990-03-01 YU YU39790A patent/YU47507B/sh unknown
- 1990-03-02 ES ES9000613A patent/ES2021956A6/es not_active Expired - Lifetime
- 1990-03-02 FI FI901094A patent/FI94344C/fi not_active IP Right Cessation
- 1990-03-02 NL NL9000491A patent/NL9000491A/nl not_active Application Discontinuation
- 1990-03-02 RU SU904743359A patent/RU1776261C/ru active
- 1990-03-02 CA CA002011325A patent/CA2011325A1/en not_active Abandoned
- 1990-03-02 IT IT19556A patent/IT1241410B/it active IP Right Grant
- 1990-03-02 AT AT0050190A patent/AT399152B/de not_active IP Right Cessation
- 1990-03-02 PL PL90284145A patent/PL163565B1/pl unknown
- 1990-03-02 JP JP2049706A patent/JPH032185A/ja active Pending
- 1990-03-02 DD DD90338351A patent/DD292461A5/de not_active IP Right Cessation
- 1990-03-02 FR FR9002635A patent/FR2643904B1/fr not_active Expired - Fee Related
- 1990-03-02 GB GB9004741A patent/GB2228733B/en not_active Expired - Lifetime
- 1990-03-02 US US07/487,412 patent/US5064826A/en not_active Expired - Fee Related
- 1990-03-02 GR GR900100149A patent/GR1000743B/el unknown
- 1990-03-05 DE DE4006873A patent/DE4006873A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE4006873A1 (de) | 1990-09-06 |
| DD292461A5 (de) | 1991-08-01 |
| IT9019556A0 (it) | 1990-03-02 |
| FR2643904B1 (fr) | 1993-02-05 |
| YU39790A (en) | 1991-10-31 |
| IT1241410B (it) | 1994-01-14 |
| FI94344C (fi) | 1995-08-25 |
| GB2228733A (en) | 1990-09-05 |
| CA2011325A1 (en) | 1990-09-03 |
| KR900014395A (ko) | 1990-10-23 |
| IT9019556A1 (it) | 1990-09-04 |
| PL163565B1 (pl) | 1994-04-29 |
| HUT54374A (en) | 1991-02-28 |
| GB9004741D0 (en) | 1990-04-25 |
| HU205117B (en) | 1992-03-30 |
| YU47507B (sh) | 1995-10-03 |
| NL9000491A (nl) | 1990-10-01 |
| CH681454A5 (el) | 1993-03-31 |
| GR900100149A (en) | 1990-07-31 |
| JPH032185A (ja) | 1991-01-08 |
| AT399152B (de) | 1995-03-27 |
| RU1776261C (ru) | 1992-11-15 |
| FI94344B (fi) | 1995-05-15 |
| US5064826A (en) | 1991-11-12 |
| ES2021956A6 (es) | 1991-11-16 |
| ATA50190A (de) | 1994-08-15 |
| FR2643904A1 (fr) | 1990-09-07 |
| FI901094A0 (fi) | 1990-03-02 |
| GB2228733B (en) | 1992-06-17 |
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