ATE48999T1 - Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE48999T1
ATE48999T1 AT86100391T AT86100391T ATE48999T1 AT E48999 T1 ATE48999 T1 AT E48999T1 AT 86100391 T AT86100391 T AT 86100391T AT 86100391 T AT86100391 T AT 86100391T AT E48999 T1 ATE48999 T1 AT E48999T1
Authority
AT
Austria
Prior art keywords
alkyl
preparation
piperazine
pharmaceutical compositions
compositions containing
Prior art date
Application number
AT86100391T
Other languages
English (en)
Inventor
Sergio Mantegani
Aldemio Temperilli
Gabriella Traquandi
Alessandro Rossi
Lorenzo Pegrassi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Application granted granted Critical
Publication of ATE48999T1 publication Critical patent/ATE48999T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
AT86100391T 1985-01-16 1986-01-14 Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE48999T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858501078A GB8501078D0 (en) 1985-01-16 1985-01-16 Piperazin-1-yl-ergo-line derivatives
EP86100391A EP0197241B1 (de) 1985-01-16 1986-01-14 Piperazin-1-yl-ergolinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE48999T1 true ATE48999T1 (de) 1990-01-15

Family

ID=10572936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86100391T ATE48999T1 (de) 1985-01-16 1986-01-14 Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (19)

Country Link
US (1) US4728649A (de)
EP (1) EP0197241B1 (de)
JP (1) JPS61167686A (de)
AT (1) ATE48999T1 (de)
AU (1) AU581280B2 (de)
CA (1) CA1243670A (de)
CS (2) CS252840B2 (de)
DE (1) DE3667789D1 (de)
DK (1) DK16186A (de)
FI (1) FI84825C (de)
GB (1) GB8501078D0 (de)
GR (1) GR860071B (de)
HK (1) HK95890A (de)
HU (1) HU195215B (de)
IE (1) IE58689B1 (de)
MY (1) MY103696A (de)
SG (1) SG80590G (de)
SU (1) SU1500160A3 (de)
ZA (1) ZA86268B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0317269B1 (de) * 1987-11-20 1992-03-04 FARMITALIA CARLO ERBA S.r.l. Ergolinderivate mit Antiparkinsonwirkung
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
ATE131167T1 (de) * 1990-01-25 1995-12-15 Pharmacia Spa Verfahren zur herstellung von ergolinderivaten.
GB9006772D0 (en) * 1990-03-27 1990-05-23 Erba Carlo Spa 4-piperidinyl-ergoline derivatives
EP0628042B1 (de) * 1992-12-24 2001-08-16 PHARMACIA & UPJOHN S.p.A. Serotoninergische ergolin derivate
WO1995005176A1 (en) * 1993-08-18 1995-02-23 Alcon Laboratories, Inc. Use of ergoline derivatives for the treatment of glaucoma
GB9711043D0 (en) * 1997-05-29 1997-07-23 Ciba Geigy Ag Organic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6818658A (de) * 1968-01-18 1969-07-22
CH615181A5 (en) * 1975-05-21 1980-01-15 Sandoz Ag Process for the preparation of novel ergolene derivatives
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
BE879822A (fr) * 1979-02-20 1980-03-03 Erba Farmitalia Derives de l'ergoline
PH21123A (en) * 1983-04-28 1987-07-27 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
AU581280B2 (en) 1989-02-16
IE58689B1 (en) 1993-11-03
EP0197241A1 (de) 1986-10-15
US4728649A (en) 1988-03-01
CA1243670A (en) 1988-10-25
EP0197241B1 (de) 1989-12-27
JPH0524918B2 (de) 1993-04-09
GR860071B (en) 1986-05-14
DE3667789D1 (de) 1990-02-01
FI84825B (fi) 1991-10-15
HUT40120A (en) 1986-11-28
IE860086L (en) 1986-07-16
GB8501078D0 (en) 1985-02-20
DK16186A (da) 1986-07-17
JPS61167686A (ja) 1986-07-29
SG80590G (en) 1990-11-23
FI860157A (fi) 1986-07-17
FI84825C (fi) 1992-01-27
CS415391A3 (en) 1992-05-13
AU5226086A (en) 1986-07-24
FI860157A0 (fi) 1986-01-13
HK95890A (en) 1990-11-23
MY103696A (en) 1993-08-28
SU1500160A3 (ru) 1989-08-07
CS32986A2 (en) 1987-03-12
HU195215B (en) 1988-04-28
ZA86268B (en) 1986-09-24
CS252840B2 (en) 1987-10-15
DK16186D0 (da) 1986-01-14

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