DE3667789D1 - Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
DE3667789D1
DE3667789D1 DE8686100391T DE3667789T DE3667789D1 DE 3667789 D1 DE3667789 D1 DE 3667789D1 DE 8686100391 T DE8686100391 T DE 8686100391T DE 3667789 T DE3667789 T DE 3667789T DE 3667789 D1 DE3667789 D1 DE 3667789D1
Authority
DE
Germany
Prior art keywords
alkyl
piperazine
production
same
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686100391T
Other languages
English (en)
Inventor
Sergio Mantegani
Aldemio Temperilli
Gabriella Traquandi
Alessandro Rossi
Lorenzo Pegrassi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3667789D1 publication Critical patent/DE3667789D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE8686100391T 1985-01-16 1986-01-14 Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. Expired - Fee Related DE3667789D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858501078A GB8501078D0 (en) 1985-01-16 1985-01-16 Piperazin-1-yl-ergo-line derivatives

Publications (1)

Publication Number Publication Date
DE3667789D1 true DE3667789D1 (de) 1990-02-01

Family

ID=10572936

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686100391T Expired - Fee Related DE3667789D1 (de) 1985-01-16 1986-01-14 Piperazin-1-yl-ergolinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (19)

Country Link
US (1) US4728649A (de)
EP (1) EP0197241B1 (de)
JP (1) JPS61167686A (de)
AT (1) ATE48999T1 (de)
AU (1) AU581280B2 (de)
CA (1) CA1243670A (de)
CS (2) CS252840B2 (de)
DE (1) DE3667789D1 (de)
DK (1) DK16186A (de)
FI (1) FI84825C (de)
GB (1) GB8501078D0 (de)
GR (1) GR860071B (de)
HK (1) HK95890A (de)
HU (1) HU195215B (de)
IE (1) IE58689B1 (de)
MY (1) MY103696A (de)
SG (1) SG80590G (de)
SU (1) SU1500160A3 (de)
ZA (1) ZA86268B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3868866D1 (de) * 1987-11-20 1992-04-09 Erba Carlo Spa Ergolinderivate mit antiparkinsonwirkung.
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
ES2083564T3 (es) * 1990-01-25 1996-04-16 Pharmacia Spa Procedimiento para la preparacion de derivados de ergolina.
GB9006772D0 (en) * 1990-03-27 1990-05-23 Erba Carlo Spa 4-piperidinyl-ergoline derivatives
TW252979B (de) * 1992-12-24 1995-08-01 Erba Carlo Spa
EP0664705B1 (de) * 1993-08-18 2000-10-04 Alcon Laboratories, Inc. Zusammensetzungen von ergolinderivaten zur behandlung des glaukoms
GB9711043D0 (en) * 1997-05-29 1997-07-23 Ciba Geigy Ag Organic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6818658A (de) * 1968-01-18 1969-07-22
CH615181A5 (en) * 1975-05-21 1980-01-15 Sandoz Ag Process for the preparation of novel ergolene derivatives
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
BE879822A (fr) * 1979-02-20 1980-03-03 Erba Farmitalia Derives de l'ergoline
PH21123A (en) * 1983-04-28 1987-07-27 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
FI860157A (fi) 1986-07-17
HK95890A (en) 1990-11-23
ATE48999T1 (de) 1990-01-15
HU195215B (en) 1988-04-28
DK16186D0 (da) 1986-01-14
JPH0524918B2 (de) 1993-04-09
CS252840B2 (en) 1987-10-15
EP0197241A1 (de) 1986-10-15
IE860086L (en) 1986-07-16
AU581280B2 (en) 1989-02-16
MY103696A (en) 1993-08-28
CS32986A2 (en) 1987-03-12
DK16186A (da) 1986-07-17
GR860071B (en) 1986-05-14
FI84825B (fi) 1991-10-15
FI860157A0 (fi) 1986-01-13
CS415391A3 (en) 1992-05-13
EP0197241B1 (de) 1989-12-27
GB8501078D0 (en) 1985-02-20
ZA86268B (en) 1986-09-24
AU5226086A (en) 1986-07-24
SG80590G (en) 1990-11-23
JPS61167686A (ja) 1986-07-29
IE58689B1 (en) 1993-11-03
HUT40120A (en) 1986-11-28
SU1500160A3 (ru) 1989-08-07
US4728649A (en) 1988-03-01
FI84825C (fi) 1992-01-27
CA1243670A (en) 1988-10-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee