GEP20166448B - Ophthalmic solution containing diquafosol, method for producing same, and method for preventing formation of insoluble precipitate - Google Patents
Ophthalmic solution containing diquafosol, method for producing same, and method for preventing formation of insoluble precipitateInfo
- Publication number
- GEP20166448B GEP20166448B GEAP201113176A GEAP2011013176A GEP20166448B GE P20166448 B GEP20166448 B GE P20166448B GE AP201113176 A GEAP201113176 A GE AP201113176A GE AP2011013176 A GEAP2011013176 A GE AP2011013176A GE P20166448 B GEP20166448 B GE P20166448B
- Authority
- GE
- Georgia
- Prior art keywords
- solution containing
- ophthalmic solution
- producing same
- insoluble precipitate
- preventing formation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010291463 | 2010-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20166448B true GEP20166448B (en) | 2016-03-25 |
Family
ID=46383087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP201113176A GEP20166448B (en) | 2010-12-28 | 2011-12-27 | Ophthalmic solution containing diquafosol, method for producing same, and method for preventing formation of insoluble precipitate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20140221306A1 (fr) |
| EP (1) | EP2659894A4 (fr) |
| JP (1) | JP2012149057A (fr) |
| KR (1) | KR20140003493A (fr) |
| CN (1) | CN103282039A (fr) |
| AU (1) | AU2011350762B2 (fr) |
| BR (1) | BR112013016008B1 (fr) |
| CA (1) | CA2823148A1 (fr) |
| EA (1) | EA027736B1 (fr) |
| GE (1) | GEP20166448B (fr) |
| MX (1) | MX2013007502A (fr) |
| MY (1) | MY161032A (fr) |
| SG (2) | SG191389A1 (fr) |
| TW (1) | TW201306844A (fr) |
| UA (1) | UA113839C2 (fr) |
| WO (1) | WO2012090994A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5625081B2 (ja) * | 2012-03-26 | 2014-11-12 | 参天製薬株式会社 | ジクアホソル含有点眼液 |
| MY182507A (en) * | 2014-12-25 | 2021-01-25 | Santen Pharmaceutical Co Ltd | Aqueous ophthalmic solution |
| TW201707710A (zh) | 2015-06-05 | 2017-03-01 | 參天製藥股份有限公司 | 特徵爲用於滴入戴著軟性隱形眼鏡的乾眼症患者的眼睛之乾眼症治療劑 |
| WO2019168023A1 (fr) | 2018-02-28 | 2019-09-06 | 参天製薬株式会社 | Composition ophtalmique comprenant du diquafosol et un polymère cationique |
| CN108853016A (zh) * | 2018-09-26 | 2018-11-23 | 广州大光制药有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
| WO2020175525A1 (fr) * | 2019-02-27 | 2020-09-03 | 参天製薬株式会社 | Composition ophtalmique contenant du diquafosol ou un sel de celui-ci, un polymère à base de vinyle et un polymère à base de cellulose |
| KR102656181B1 (ko) * | 2019-08-27 | 2024-04-08 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물 |
| JP7230169B2 (ja) * | 2020-12-25 | 2023-02-28 | 参天製薬株式会社 | ジクアホソルまたはその塩、銀塩およびイオン性等張化剤を含有する水性点眼液 |
| CN113712910A (zh) * | 2021-08-05 | 2021-11-30 | 广州市桐晖药业有限公司 | 一种滴眼液及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| ATE261982T1 (de) | 1997-07-25 | 2004-04-15 | Inspire Pharmaceuticals Inc | Salze von di(uridine 5'-tetraphosphate), verfahren zur herstellung und verwendungen davon |
| BR0111297A (pt) * | 2000-05-30 | 2004-01-06 | Santen Pharmaceutical Co Ltd | Promotor de migração epitelial corneana |
| JP4003008B2 (ja) * | 2000-05-30 | 2007-11-07 | 参天製薬株式会社 | 角膜上皮伸展促進剤 |
| JP2003160491A (ja) * | 2001-09-11 | 2003-06-03 | Santen Pharmaceut Co Ltd | ジウリジンリン酸含有点眼液 |
| JP4168071B2 (ja) | 2005-12-08 | 2008-10-22 | 興和株式会社 | 点眼用組成物 |
| EP2614838B1 (fr) * | 2010-09-10 | 2016-04-20 | Santen Pharmaceutical Co., Ltd. | Diquafosol et l'acide hyaluronique ou ses sels pour le traitement de l'oeil sec |
-
2011
- 2011-12-27 EA EA201390985A patent/EA027736B1/ru unknown
- 2011-12-27 EP EP11852288.7A patent/EP2659894A4/fr not_active Withdrawn
- 2011-12-27 WO PCT/JP2011/080179 patent/WO2012090994A1/fr active Application Filing
- 2011-12-27 JP JP2011285977A patent/JP2012149057A/ja not_active Withdrawn
- 2011-12-27 GE GEAP201113176A patent/GEP20166448B/en unknown
- 2011-12-27 SG SG2013050000A patent/SG191389A1/en unknown
- 2011-12-27 SG SG10201508591UA patent/SG10201508591UA/en unknown
- 2011-12-27 UA UAA201309390A patent/UA113839C2/uk unknown
- 2011-12-27 AU AU2011350762A patent/AU2011350762B2/en not_active Ceased
- 2011-12-27 KR KR1020137019146A patent/KR20140003493A/ko not_active Application Discontinuation
- 2011-12-27 BR BR112013016008-0A patent/BR112013016008B1/pt not_active IP Right Cessation
- 2011-12-27 CN CN2011800632699A patent/CN103282039A/zh active Pending
- 2011-12-27 CA CA2823148A patent/CA2823148A1/fr not_active Abandoned
- 2011-12-27 TW TW100148759A patent/TW201306844A/zh unknown
- 2011-12-27 MX MX2013007502A patent/MX2013007502A/es unknown
- 2011-12-27 MY MYPI2013002461A patent/MY161032A/en unknown
- 2011-12-27 US US13/976,408 patent/US20140221306A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW201306844A (zh) | 2013-02-16 |
| BR112013016008A2 (pt) | 2018-07-10 |
| BR112013016008B1 (pt) | 2021-06-29 |
| EP2659894A4 (fr) | 2014-12-10 |
| SG10201508591UA (en) | 2015-11-27 |
| EP2659894A1 (fr) | 2013-11-06 |
| SG191389A1 (en) | 2013-07-31 |
| CA2823148A1 (fr) | 2012-07-05 |
| JP2012149057A (ja) | 2012-08-09 |
| WO2012090994A1 (fr) | 2012-07-05 |
| EA027736B1 (ru) | 2017-08-31 |
| AU2011350762B2 (en) | 2017-04-06 |
| CN103282039A (zh) | 2013-09-04 |
| KR20140003493A (ko) | 2014-01-09 |
| US20140221306A1 (en) | 2014-08-07 |
| EA201390985A1 (ru) | 2013-11-29 |
| UA113839C2 (xx) | 2017-03-27 |
| MY161032A (en) | 2017-04-03 |
| MX2013007502A (es) | 2013-08-01 |
| AU2011350762A1 (en) | 2013-07-25 |
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