GB873243A - Novel dicarbamates - Google Patents
Novel dicarbamatesInfo
- Publication number
- GB873243A GB873243A GB9068/60A GB906860A GB873243A GB 873243 A GB873243 A GB 873243A GB 9068/60 A GB9068/60 A GB 9068/60A GB 906860 A GB906860 A GB 906860A GB 873243 A GB873243 A GB 873243A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ethylpropyl
- methyl
- propanediol
- ethyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises 2-methyl-2-(1-ethylpropyl)-1:3-propanediol dicarbamate and 2-ethyl-2-(1-ethylpropyl)-1:3-propanediol dicarbamate. They may be prepared by reacting the free diol with either (1) phosgene and then ammonia; or (2) a low molecular weight urethane; or (3) cyanic acid in an anhydrous medium. Examples are given. 2-Methyl-2-(1-ethylpropyl)-1:3-propanediol is prepared by lithium aluminium hydride reduction of diethyl (methyl-1-ethylpropyl)-malonate, itself prepared from diethyl methyl-malonate and 3-bromopentane. 2-Ethyl-2-(1-ethylpropyl)-1:3-propanediol and diethyl (ethyl-1-ethylpropyl)-malonate are prepared similarly.ALSO:Pharmaceutical compositions contain, as essential active ingredient, either 2-methyl-2-(1-ethylpropyl)-1 : 3-propanediol dicarbamate or 2 - ethyl - 2 - (1 - ethylpropyl) - 1 : 3 - propanediol dicarbamate. They may be formulated as pills, tablets, capsules or solutions for oral administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US873243XA | 1959-03-16 | 1959-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB873243A true GB873243A (en) | 1961-07-19 |
Family
ID=22204494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9068/60A Expired GB873243A (en) | 1959-03-16 | 1960-03-15 | Novel dicarbamates |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB873243A (en) |
-
1960
- 1960-03-15 GB GB9068/60A patent/GB873243A/en not_active Expired
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