GB798568A - 2-phenyl-1,3-propanediol dicarbamate - Google Patents
2-phenyl-1,3-propanediol dicarbamateInfo
- Publication number
- GB798568A GB798568A GB1220/57A GB122057A GB798568A GB 798568 A GB798568 A GB 798568A GB 1220/57 A GB1220/57 A GB 1220/57A GB 122057 A GB122057 A GB 122057A GB 798568 A GB798568 A GB 798568A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- dicarbamate
- propanediol
- preparation
- propanediol dicarbamate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises 2-phenyl-1 : 3-propanediol dicarbamate and its preparation by reacting 2-phenyl-1 : 3-propanediol with phosgene to form the corresponding di-chlorocarbonate and converting this to the dicarbamate by ammoniation. Preferably, an acid-binding agent such as sodium hydroxide, 1 : 5 - dimethyl - 2 - phenyl - 3 - pyrazolone or a dialkylaniline is added in the first stage of this process. Either anhydrous or aqueous ammonia may be used to form the dicarbamate. Examples describe the preparation of 2-phenyl-1 : 3-propanediol by reduction of diethyl phenyl malonate with lithium aluminium hydride and conversion of the diol to the dicarbamate by the process of the invention.ALSO:A pharmaceutical preparation possessing anti-convulsant activity comprises 2-phenyl-1 : 3-propanediol dicarbamate formed into pills, tablets or capsules or dissolved in a solvent such as a mixture of water and polyethylene glycol.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US798568XA | 1956-01-13 | 1956-01-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB798568A true GB798568A (en) | 1958-07-23 |
Family
ID=22153235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1220/57A Expired GB798568A (en) | 1956-01-13 | 1957-01-11 | 2-phenyl-1,3-propanediol dicarbamate |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB798568A (en) |
-
1957
- 1957-01-11 GB GB1220/57A patent/GB798568A/en not_active Expired
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