GB930430A - Carbamic acid ester - Google Patents
Carbamic acid esterInfo
- Publication number
- GB930430A GB930430A GB3256561A GB3256561A GB930430A GB 930430 A GB930430 A GB 930430A GB 3256561 A GB3256561 A GB 3256561A GB 3256561 A GB3256561 A GB 3256561A GB 930430 A GB930430 A GB 930430A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cyclopentyl
- methyl
- propanediol
- diethyl
- malonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises 2-cyclopentyl-2-methyl-1 : 3-propanedio dicarbamate of the formula:- <FORM:0930430/IV(a)/1> and the preparation thereof by reacting 2-cyclopentyl-2-methyl-1 : 3-propanediol with an alkali metal isocyanate in the presence of a mineral acid. 2-Cyclopentyl-2-methyl-1 : 3-propanediol is prepared by lithium aluminium hydride reduction of diethyl-a -cyclopentyl-a -methyl-malonate. Diethyl-a -cyclopentyl-a -methyl-malonate is prepared by reacting the sodium salt of diethyl-a -methylamalonate with cyclopentyl bromide. 2-Cyclopentyl-2-methyl-1 : 3-propanediol dicarbonate of the above general formula is used in conjunction with solid or liquid pharmaceutical excipients as a tranquilliser and a muscle relaxer. The compositions may take the form of tablets, dragees, capsules, suspensions, solutions and emulsions, and are suitable for enteral (oral) or parenteral administration.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5513760A | 1960-09-12 | 1960-09-12 | |
US11088361A | 1961-05-18 | 1961-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB930430A true GB930430A (en) | 1963-07-03 |
Family
ID=26733884
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB712363A Expired GB934207A (en) | 1960-09-12 | 1961-09-11 | Carbamic acid esters |
GB3256561A Expired GB930430A (en) | 1960-09-12 | 1961-09-11 | Carbamic acid ester |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB712363A Expired GB934207A (en) | 1960-09-12 | 1961-09-11 | Carbamic acid esters |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH424763A (en) |
ES (1) | ES270394A1 (en) |
GB (2) | GB934207A (en) |
-
1961
- 1961-09-11 GB GB712363A patent/GB934207A/en not_active Expired
- 1961-09-11 CH CH1054061A patent/CH424763A/en unknown
- 1961-09-11 GB GB3256561A patent/GB930430A/en not_active Expired
- 1961-09-11 ES ES270394A patent/ES270394A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CH424763A (en) | 1966-11-30 |
ES270394A1 (en) | 1962-05-01 |
GB934207A (en) | 1963-08-14 |
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