GB1015787A - Tris-(p-methoxyphenyl)ethylene derivatives - Google Patents
Tris-(p-methoxyphenyl)ethylene derivativesInfo
- Publication number
- GB1015787A GB1015787A GB2989062A GB2989062A GB1015787A GB 1015787 A GB1015787 A GB 1015787A GB 2989062 A GB2989062 A GB 2989062A GB 2989062 A GB2989062 A GB 2989062A GB 1015787 A GB1015787 A GB 1015787A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methoxyphenyl
- tris
- ethylene derivatives
- ethylene
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of formula <FORM:1015787/C2/1> wherein X is a carboxylic ester, dialkylamide or hydroxymethyl group, and their preparation by (a) esterification or reduction of the corresponding carboxylic acid or (b) reaction of tri-(p - methoxyphenyl) - ethylene with an alkyl lithium and N,N-dimethylchloroformamide. The compounds of the invention have estrogenic activity and may be administered in pharmaceutical preparations for oral use, such as tablets, capsules and dragees.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2989062A GB1015787A (en) | 1962-08-03 | 1962-08-03 | Tris-(p-methoxyphenyl)ethylene derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2989062A GB1015787A (en) | 1962-08-03 | 1962-08-03 | Tris-(p-methoxyphenyl)ethylene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1015787A true GB1015787A (en) | 1966-01-05 |
Family
ID=10298841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2989062A Expired GB1015787A (en) | 1962-08-03 | 1962-08-03 | Tris-(p-methoxyphenyl)ethylene derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1015787A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4696949A (en) * | 1982-06-25 | 1987-09-29 | Farmos Group Ltd. | Novel tri-phenyl alkane and alkene derivatives and their preparation and use |
US5491173A (en) * | 1982-06-25 | 1996-02-13 | Orion-Yhtyma Oy | Tri-phenyl alkene derivatives and their preparation and use |
US5770609A (en) | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5945456A (en) * | 1993-05-13 | 1999-08-31 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6117911A (en) | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US6197789B1 (en) | 1995-06-07 | 2001-03-06 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US8067022B2 (en) | 1992-09-25 | 2011-11-29 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US20150140493A1 (en) * | 2013-11-18 | 2015-05-21 | Toyo Gosei Co., Ltd. | Compounders for enhancing generation of chemical species |
-
1962
- 1962-08-03 GB GB2989062A patent/GB1015787A/en not_active Expired
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4696949A (en) * | 1982-06-25 | 1987-09-29 | Farmos Group Ltd. | Novel tri-phenyl alkane and alkene derivatives and their preparation and use |
US5491173A (en) * | 1982-06-25 | 1996-02-13 | Orion-Yhtyma Oy | Tri-phenyl alkene derivatives and their preparation and use |
US8067022B2 (en) | 1992-09-25 | 2011-11-29 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US6262079B1 (en) | 1992-09-25 | 2001-07-17 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5770609A (en) | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6569441B2 (en) | 1993-01-28 | 2003-05-27 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6166090A (en) | 1993-05-13 | 2000-12-26 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US5945456A (en) * | 1993-05-13 | 1999-08-31 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US8158670B2 (en) | 1995-02-15 | 2012-04-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US6197789B1 (en) | 1995-06-07 | 2001-03-06 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
US6410587B1 (en) | 1997-04-11 | 2002-06-25 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US6117911A (en) | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US20150140493A1 (en) * | 2013-11-18 | 2015-05-21 | Toyo Gosei Co., Ltd. | Compounders for enhancing generation of chemical species |
US9593060B2 (en) * | 2013-11-18 | 2017-03-14 | Toyo Gosei Co., Ltd | Compounds for enhancing generation of chemical species |
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