ES8104222A1 - Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates. - Google Patents
Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates.Info
- Publication number
- ES8104222A1 ES8104222A1 ES480265A ES480265A ES8104222A1 ES 8104222 A1 ES8104222 A1 ES 8104222A1 ES 480265 A ES480265 A ES 480265A ES 480265 A ES480265 A ES 480265A ES 8104222 A1 ES8104222 A1 ES 8104222A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- alkylcarbapenems
- intermediates
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
This invention provides the antibacterial compounds of the formula (I): < CHEM > and salts and cleavable esters thereof wherein A is a C=CH-CH3 or CH-CH2-CH3 group and Y is a -S-CH2-CH2-, -S-CH=CH- or -SO-CH=CH- group. The invention also relates to process for the preparation of the said compounds and pharmaceutical compositions containing them.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1810178 | 1978-05-06 | ||
GB2435878 | 1978-05-30 | ||
GB7849841 | 1978-12-22 | ||
GB7902920 | 1979-01-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8104222A1 true ES8104222A1 (en) | 1981-04-16 |
ES480265A0 ES480265A0 (en) | 1981-04-16 |
Family
ID=27448410
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES480265A Granted ES480265A0 (en) | 1978-05-06 | 1979-05-04 | A PROCEDURE FOR THE PREPARATION OF ACID DERIVATIVES 7-OXO-1-AZA-BICYCLE (3,2,0) HEPT-2-EN-2-CARBOXILICO |
ES488211A Expired ES8101592A1 (en) | 1978-05-06 | 1980-02-01 | Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES488211A Expired ES8101592A1 (en) | 1978-05-06 | 1980-02-01 | Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0005349A1 (en) |
JP (1) | JPS54145695A (en) |
AU (1) | AU4664979A (en) |
CA (1) | CA1125292A (en) |
DK (1) | DK186279A (en) |
ES (2) | ES480265A0 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55136282A (en) * | 1979-04-06 | 1980-10-23 | Shionogi & Co Ltd | Novel antibiotic pa-31088-4 |
DE3070269D1 (en) * | 1979-08-10 | 1985-04-18 | Beecham Group Plc | Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation |
JPS5683489A (en) * | 1979-12-12 | 1981-07-08 | Shionogi & Co Ltd | New antibiotic pa-39504-x1 and it preparation |
JPS5740485A (en) * | 1980-08-25 | 1982-03-06 | Shionogi & Co Ltd | Novel antibiotic pa-39504-x3 and its preparation |
JPS5764693A (en) * | 1980-10-07 | 1982-04-19 | Kowa Co | Novel carbapenem compound and its preparation |
EP0050961B1 (en) * | 1980-10-24 | 1985-05-22 | Kowa Company, Ltd. | Novel antibiotics, a process for producing the same, medical compositions containing the same, and a novel strain of the genus streptomyces for use in producing the same |
WO1985001502A1 (en) * | 1983-09-28 | 1985-04-11 | Takeda Chemical Industries, Ltd. | 7-oxo-1-azabicyclo ad3.2.0 bd hept-2-ene-2-carboxylic acid derivatives, process for their preparation, and their use |
SI9600371B (en) * | 1996-12-18 | 2005-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Ethylidene derivatives of tricyclic carbapenemes |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7802826A (en) * | 1977-04-08 | 1978-10-10 | Merck & Co Inc | THIENAMYCINE DERIVATIVE, METHOD FOR PREPARING THEREOF, AND PHARMACEUTICAL PREPARATIONS. |
EP0001567B1 (en) * | 1977-10-13 | 1981-12-02 | Sanraku-Ocean Co., Ltd. | Thienamycin related antibiotics ps-6 and ps-7, process for their production and compositions containing them |
-
1979
- 1979-04-26 EP EP79300712A patent/EP0005349A1/en not_active Ceased
- 1979-05-03 AU AU46649/79A patent/AU4664979A/en not_active Abandoned
- 1979-05-04 DK DK186279A patent/DK186279A/en not_active Application Discontinuation
- 1979-05-04 CA CA326,924A patent/CA1125292A/en not_active Expired
- 1979-05-04 ES ES480265A patent/ES480265A0/en active Granted
- 1979-05-07 JP JP5621579A patent/JPS54145695A/en active Pending
-
1980
- 1980-02-01 ES ES488211A patent/ES8101592A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES488211A0 (en) | 1980-12-16 |
CA1125292A (en) | 1982-06-08 |
JPS54145695A (en) | 1979-11-14 |
ES8101592A1 (en) | 1980-12-16 |
DK186279A (en) | 1979-12-10 |
AU4664979A (en) | 1979-11-08 |
EP0005349A1 (en) | 1979-11-14 |
ES480265A0 (en) | 1981-04-16 |
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