GB857547A - Trifluoromethyl-phenothiazine derivatives - Google Patents
Trifluoromethyl-phenothiazine derivativesInfo
- Publication number
- GB857547A GB857547A GB31044/60A GB3104460A GB857547A GB 857547 A GB857547 A GB 857547A GB 31044/60 A GB31044/60 A GB 31044/60A GB 3104460 A GB3104460 A GB 3104460A GB 857547 A GB857547 A GB 857547A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- compound
- trifluoromethyl
- alkanoyl
- halide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AZSIPSZDDPHYPD-UHFFFAOYSA-N 1-(trifluoromethyl)-10h-phenothiazine Chemical class S1C2=CC=CC=C2NC2=C1C=CC=C2C(F)(F)F AZSIPSZDDPHYPD-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 2
- -1 alkanoyl halide Chemical class 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 150000004820 halides Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UQZPGHOJMQTOHB-UHFFFAOYSA-N 2-chloro-n-(2-chloroethyl)-n-ethylethanamine Chemical compound ClCCN(CC)CCCl UQZPGHOJMQTOHB-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- WJCRAVDPIMWFPG-UHFFFAOYSA-N n-phenyl-3-(trifluoromethyl)aniline Chemical compound FC(F)(F)C1=CC=CC(NC=2C=CC=CC=2)=C1 WJCRAVDPIMWFPG-UHFFFAOYSA-N 0.000 abstract 1
- LFQULJPVXNYWAG-UHFFFAOYSA-N sodium;phenylmethanolate Chemical compound [Na]OCC1=CC=CC=C1 LFQULJPVXNYWAG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US857546XA | 1955-12-23 | 1955-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB857547A true GB857547A (en) | 1960-12-29 |
Family
ID=22193722
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31044/60A Expired GB857547A (en) | 1955-12-23 | 1956-12-12 | Trifluoromethyl-phenothiazine derivatives |
| GB37978/56A Expired GB857546A (en) | 1955-12-23 | 1956-12-12 | Trifluoromethyl-phenothiazine derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB37978/56A Expired GB857546A (en) | 1955-12-23 | 1956-12-12 | Trifluoromethyl-phenothiazine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| CY (1) | CY280A (enrdf_load_stackoverflow) |
| DE (1) | DE1095836B (enrdf_load_stackoverflow) |
| FR (1) | FR1209854A (enrdf_load_stackoverflow) |
| GB (2) | GB857547A (enrdf_load_stackoverflow) |
| NL (1) | NL106170C (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5227779A (en) * | 1975-08-29 | 1977-03-02 | Eisai Co Ltd | Phenothiazine compounds and medicaments containing the same |
| EP2061788A4 (en) * | 2006-09-01 | 2010-10-06 | Immune Control Inc | NOVEL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ACTIVATED LYMPHOCYTES |
| US8637503B2 (en) | 2003-05-16 | 2014-01-28 | Board Of Regents, The University Of Texas System | Phenothiazine enantiomers as agents for the prevention of bone loss |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL108827C (enrdf_load_stackoverflow) * | 1956-04-09 | |||
| AU2017279905B2 (en) * | 2016-06-23 | 2021-10-14 | Bioimics Ab | Anti-infective heterocyclic compounds and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE910301C (de) * | 1950-12-21 | 1954-04-29 | Rhone Poulenc Sa | Verfahren zur Herstellung von neuen Phenthiazinderivaten |
-
0
- NL NL106170D patent/NL106170C/xx active
-
1956
- 1956-04-27 FR FR1209854D patent/FR1209854A/fr not_active Expired
- 1956-12-08 DE DEO5235A patent/DE1095836B/de active Pending
- 1956-12-12 GB GB31044/60A patent/GB857547A/en not_active Expired
- 1956-12-12 GB GB37978/56A patent/GB857546A/en not_active Expired
-
1964
- 1964-03-18 CY CY28064A patent/CY280A/xx unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5227779A (en) * | 1975-08-29 | 1977-03-02 | Eisai Co Ltd | Phenothiazine compounds and medicaments containing the same |
| US4139632A (en) * | 1975-08-29 | 1979-02-13 | Eisai Co., Ltd. | Psychotropic 2-trifluoromethyl-10-[3-(3-hydroxy-pyrrolidino)-propyl]-phenothiazine compounds |
| US8637503B2 (en) | 2003-05-16 | 2014-01-28 | Board Of Regents, The University Of Texas System | Phenothiazine enantiomers as agents for the prevention of bone loss |
| EP2061788A4 (en) * | 2006-09-01 | 2010-10-06 | Immune Control Inc | NOVEL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ACTIVATED LYMPHOCYTES |
| US7923445B2 (en) | 2006-09-01 | 2011-04-12 | Immune Control, Inc. | Methods for treatment of diseases related to activated lymphocytes |
| US7981885B2 (en) | 2006-09-01 | 2011-07-19 | Immune Control Inc. | Compositions for treatment of diseases related to activated lymphocytes |
Also Published As
| Publication number | Publication date |
|---|---|
| FR1209854A (fr) | 1960-03-04 |
| NL106170C (enrdf_load_stackoverflow) | |
| DE1095836B (de) | 1960-12-29 |
| CY280A (en) | 1964-03-18 |
| GB857546A (en) | 1960-12-29 |
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