GB1037655A - Di(aralkyl)amines - Google Patents
Di(aralkyl)aminesInfo
- Publication number
- GB1037655A GB1037655A GB2088564A GB2088564A GB1037655A GB 1037655 A GB1037655 A GB 1037655A GB 2088564 A GB2088564 A GB 2088564A GB 2088564 A GB2088564 A GB 2088564A GB 1037655 A GB1037655 A GB 1037655A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- compound
- halogen
- formula
- reduced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New compounds of formula <FORM:1037655/C2/1> where R1 is lower (1-6 C) alkyl, R2 is halogen, R3 is hydrogen or lower alkyl, and m and n are each 1-4, and non-toxic acid addition salts thereof, are prepared by reacting a dialkoxyphenalkylamine and a compound X.CO.(CH2)n- 1PhR2, X being halogen, to form an amide of formula <FORM:1037655/C2/2> and reducing the carbonyl group, optionally followed by reaction with an alkanoyl halide to form an N,N-disubstituted amide which is reduced. Processes also mentioned are (I) performing the second acylation-reduction above as a first step to yield a compound (R1O)2-Ph-(CH2)m.NH.alkyl which can then either by acylated and reduced or reacted with a compound X(CH2)nPhR2, and (II) reacting compounds (R1O)2-Ph-(CH2)m-X and alkyl.NH.(CH1)n-Ph-R2. Pharmaceutical compositions comprise the new compounds with carriers. Oral and parenteral preparations having analgesic, sedative and anaesthetic-potentiating activity are mentioned.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2088564A GB1037655A (en) | 1964-05-20 | 1964-05-20 | Di(aralkyl)amines |
NL6505765A NL6505765A (en) | 1964-05-20 | 1965-05-06 | |
BE663997D BE663997A (en) | 1964-05-20 | 1965-05-17 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2088564A GB1037655A (en) | 1964-05-20 | 1964-05-20 | Di(aralkyl)amines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1037655A true GB1037655A (en) | 1966-08-03 |
Family
ID=10153410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2088564A Expired GB1037655A (en) | 1964-05-20 | 1964-05-20 | Di(aralkyl)amines |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE663997A (en) |
GB (1) | GB1037655A (en) |
NL (1) | NL6505765A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141962A (en) * | 1989-04-28 | 1992-08-25 | Roussel Uclaf | Amine compounds |
JP2011513377A (en) * | 2008-03-06 | 2011-04-28 | ノヴァレメッド リミテッド | Method for treating or preventing pain |
-
1964
- 1964-05-20 GB GB2088564A patent/GB1037655A/en not_active Expired
-
1965
- 1965-05-06 NL NL6505765A patent/NL6505765A/xx unknown
- 1965-05-17 BE BE663997D patent/BE663997A/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141962A (en) * | 1989-04-28 | 1992-08-25 | Roussel Uclaf | Amine compounds |
JP2011513377A (en) * | 2008-03-06 | 2011-04-28 | ノヴァレメッド リミテッド | Method for treating or preventing pain |
Also Published As
Publication number | Publication date |
---|---|
NL6505765A (en) | 1965-11-22 |
BE663997A (en) | 1965-11-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1325192A (en) | Phloroglucinol derivatives | |
GB1124285A (en) | Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them | |
GB1063749A (en) | New guanidine derivatives and processes for their production | |
GB1297386A (en) | ||
GB1069797A (en) | ª-aminoketone derivatives | |
GB1037655A (en) | Di(aralkyl)amines | |
GB1341809A (en) | Phenanthridine derivatives | |
GB1371969A (en) | Triazene derivatives their production and their medicinal use | |
GB1352288A (en) | Imidazole derivatives | |
GB1375378A (en) | ||
GB1042296A (en) | Novel dibenzoxazepinones, their preparation and compositions containing them | |
GB1526038A (en) | 5-thiazole methane amine derivatives and salts thereof processes for preparing them and pharmaceutical compositions containing them | |
GB1305725A (en) | ||
GB959993A (en) | Camphor derivatives | |
GB1071815A (en) | Phenothiazine derivatives | |
GB1322069A (en) | Aminoalkanoylaminocyclohexane derivatives | |
GB1369888A (en) | Substituted amidines | |
GB1085135A (en) | Aryl-ª-aminoketone derivatives | |
GB1318859A (en) | Imidazo-4,5-b-pyridine derivatives | |
GB1425729A (en) | 1,4-dihydropyridine compounds | |
GB1472344A (en) | Methylene dibenzocycloheptanes | |
GB1199040A (en) | Diisoeugenol Derivatives | |
GB1028099A (en) | Substituted propionanilides | |
GB1356747A (en) | ||
ES344072A1 (en) | Basically substituted 2-imidazolidone derivatives and their production |